Clinical trials: Weight Changes, Body
Severe Acute Malnutrition, Cognitive Impairment
Choline to Improve Malnutrition and Enhance Cognition
The goal of this clinical trial is to test adding choline to ready-to-use therapeutic food (RUTF) in children with severe acute malnutrition (SAM) in Malawi.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Wasting, Kwashiorkor
- Trial name
- CHIME-SAM (NCT06154174)
- Testing
- C-RUTF (Ready-to-Use Therapeutic Food with added choline), S-RUTF (Ready-to-Use Therapeutic Food without added choline), Amoxicillin
- Where
- 10 sites in Malawi
- Volunteers
- 1,500 people
- Sponsor
- Washington University School of Medicine
Osteoarthritis
Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults
The purpose of this study is to compare the effects of a calorie-restricting diet, exercise, and a combination of both in reducing knee inflammation and compressive forces in obese and overweight adults with knee osteoarthritis…
- Trial name
- NCT00381290
- Testing
- Diet, Exercise
- Where
- United States
- Volunteers
- 454 people
- Sponsor
- Wake Forest University
Weight Loss
Weight Management Demonstration Project: HEALTH
The study investigated the effectiveness and cost-effectiveness of a cognitive and behavioral weight management program, complemented by an interactive Web site and brief telephone coaching, implemented among TRICARE…
- Trial name
- HEALTH (NCT01307280)
- Testing
- RCT1, RCT2, RCT3
- Where
- 3 sites in United States
- Volunteers
- 2,395 people
- Sponsor
- RTI International
Weight Loss
An Examination of a Weight Loss Formula on Health
The aim of this study is to examine a novel weight loss formula with and without common stimulants on anthropometry and indices of cardiovascular disease risk.
- Trial name
- NB14 (NCT03395262)
- Testing
- Active with caffeine, Active without caffeine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obesity, Weight Change, Body
Life Style Modification Medical and Surgical Management in Patients With Obesity
In this is an observational study, obese patients that administed and followed in endocrinology clinic of Marmara University Medical school hospital will follow for clinical and laboratory parameters prospectively for 5 years
- Conditions
- Obesity, Weight Change, Body, Obesity; Endocrine, Obesity, Metabolically Benign
- Trial name
- NCT04417582
- Testing
- bariatric surgey
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Marmara University
Neonatal Abstinence Syndrome
RCT of High- vs. Standard-Calorie Formula for Methadone-Exposed Infants
Neonatal abstinence syndrome (NAS) symptoms contribute to poor infant weight gain. Early caloric enhancement for infants exposed to methadone is inexpensive, readily available, easy to implement and could improve early outcomes…
- Trial name
- NCT02178189
- Testing
- High Calorie Infant formula, Standard Calorie Infant Formula
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Pittsburgh
Anorexia, Cachexia
Creatine in Treating Patients With Cancer-Associated Weight Loss
RATIONALE: It is not yet known whether the supplement creatine is effective in increasing weight and improving appetite and quality of life in patients who have cancer.
- Conditions
- Anorexia, Cachexia, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
- Trial name
- NCT00081250
- Testing
- creatine monohydrate
- Where
- 220 sites in United States
- Volunteers
- 300 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Weight Change, BMI
Childhood Obesity Prevention Project in Gran Canaria
Given the alarming rates of obesity and overweight in our child population, the investigators have developed an intervention strategy, based on a multidisciplinary, school-centered approach, which addresses nutritional education…
- Conditions
- Weight Change, BMI, Activity Level, Cholesterol (total and HDL)
- Trial name
- POI (NCT06607159)
- Testing
- Implementation of healthy habits teaching protocol
- Where
- Spain
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Universitario Insular Materno Infantil
Breast Cancer, Body Weight Changes
Effects of a Paleolithic Lifestyle Intervention in Breast Cancer Patients Undergoing Radiotherapy
The study aims to test the feasibility and effects of a dietary and physical activity intervention based on evolutionary considerations in an oncological setting.
- Trial name
- NCT04574323
- Testing
- Curative radiotherapy, Paleolithic lifestyle intervention
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- MVZ Leopoldina GmbH
Metabolism, Obesity
RMR Monitoring Feasibility and Acceptability
Obesity is a leading risk factor for chronic diseases such as type 2 diabetes, cancer, and cardiovascular disease. Generic weight management programs that target dietary intake and physical activity have been shown to be…
- Conditions
- Metabolism, Obesity, Weight Loss
- Trial name
- NCT06467578
- Testing
- Breezing Portable Indirect Calorimeter
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetes Type 2, Weight Gain
Effects of Insulin Detemir and NPH Insulin on Renal Handling of Sodium, Fluid Retention, and Weight in Type 2 Diabetic Patients
Hypothesis: Changing type 2 patients treatment from Insulin Insulatard to Insulin Detemir will increase their excretion of sodium in the urine and thereby decrease their extracellular volume and body weight.
- Trial name
- Le-Na (NCT00742976)
- Testing
- Insulin Detemir; Insulin Insulatard, Insulin Detemir, Insulin Insulatard
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Weight Gain
Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth
The purpose of this pilot study is to determine whether starting metformin in conjunction with a second-generation antipsychotic (SGA) and providing information about healthy eating and activity will prevent or reduce the amount…
- Trial name
- PREVENT (NCT00617240)
- Testing
- metformin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
Effect of Transform Burn on Weight Loss
This study was undertaken to explore the effects of a Thermogenic Composition (TC) composed of dihydrocapsiate, red pepper (Capsicum annuum) fruit extract, citrus (Citrus spp) peel extract, coleus (Coleus forskholi) root extract…
- Trial name
- Transform (NCT06092840)
- Testing
- Transform Burn
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Weight Loss, Morbid Obesity
Maintenance Programme After Weight Loss
The aim of this study is to compare a weight reduction programme with and without a maintenance programme in patients with severe obesity.
- Trial name
- NCT00590655
- Testing
- weight loss programme with maintenance programme, weight loss programme
- Where
- Finland
- Volunteers
- 201 people
- Sponsor
- University of Helsinki
Obesity
Lifestyle Modification and Liraglutide
This is a 52 week, single center, open-labeled, randomized controlled trial. A total of 150 subjects with obesity, who are free of types 1 and 2 diabetes, as well as contraindications to weight loss, will be randomly assigned to…
- Trial name
- MODEL (NCT02911818)
- Testing
- CMS-recommended lifestyle counseling, Liraglutide 3.0mg, Portion-Controlled Diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Obesity, Weight Loss
Impact of the Excess Weight Loss on Mineralization Patterns of the Knee After Bariatric Operations
Evaluation of the subchondral mineralization plate after excess weight loss in patientes undergoing bariatric operation by means of CT-osteoabsorptiometry.
- Conditions
- Obesity, Weight Loss, Knee Osteoarthritis
- Trial name
- CT-OAM (NCT02404090)
- Testing
- CT-osteoarbsorptiometry
- Volunteers
- 50 people
- Sponsor
- Marko Kraljevic
Obesity (Disorder), Type 2 Diabetes Mellitus
Body Composition Changes After Initiation of GLP-1 Receptor Agonists in Adults With Obesity or Type 2 Diabetes
Researchers want to understand what happens to muscle and fat in the body after adults with obesity and/or type 2 diabetes start taking a GLP-1 receptor agonist medication (GLP-1RA), a type of drug already approved and commonly…
- Trial name
- NCT07835360
- Where
- 2 sites in Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Hypoglycemia Non-Diabetic, Gastric Bypass Status Complicating Pregnancy, Birth, or Puerperium
Bariatric Surgery and Consequences for Mother and Baby in Pregnancy
Background Roux-en-Y gastric bypass (RYGB) is a well-established treatment of obesity, most often performed in women during their reproductive years. Adverse events related to RYGB include hypoglycemia.
- Trial name
- BAMBI (NCT03713060)
- Testing
- Mixed meal test
- Where
- 2 sites in Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Obesity, Overweight
Dietary Effects on Weight Loss and Lipid Profile in Sedentary Women
Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method.
- Conditions
- Obesity, Overweight, Life Style
- Trial name
- NCT03066882
- Testing
- NCD, LCD
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Obesity
Changes in Sexual Function Following Bariatric Surgery
The main purposes of the study are to compare changes in sexual function, changes in sex hormones, and changes in body image and marital satisfaction at 12, 24, 36 and 48 months postoperatively in two groups: individuals who…
- Trial name
- NCT00670098
- Testing
- Bariatric surgery, lifestyle intervention (behavioral weight loss)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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