Clinical trials: Weight Changes, Body
Obesity, Weight Change Trajectory
Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Fractyl is evaluating Revita Duodenal Mucosal Resurfacing (DMR) in the REMAIN-1 pivotal study, which is designed to include two cohorts - an open label cohort referred to as REVEAL-1, and a randomized cohort, which includes both…
- Conditions
- Obesity, Weight Change Trajectory, Weight Change, Body
- Trial name
- REMAIN-1 (NCT06484114)
- Testing
- Revita Duodenal Mucosal Resurfacing (DMR)
- Where
- 32 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Fractyl Health Inc.
Hunger, Weight Change
Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement
This study evaluates changes in hunger perception and body composition-related measures following daily use of a commercially available dietary supplement formulated to support leptin-related metabolic signaling.
- Trial name
- NCT07442864
- Testing
- Leptin Balance Formula
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Obesity (Disorder), Weight Change
Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination
Semaglutide is a medication from the class of drugs called glucagon-like peptide-1 agonists that promote weight loss. There is little clinical data on the best strategy to achieve weight maintenance following weight reduction…
- Conditions
- Obesity (Disorder), Weight Change, Blood Pressure Monitoring, Appetite Regulation
- Trial name
- REST (NCT07294950)
- Testing
- Gradual dose reduction of semaglutide, Abrupt cessation of semaglutide
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Mount Sinai Hospital, Canada
Weight Loss, Body Fat Rate Loss
Function Definition and Clinical Validation of Digital Health App: Using Weight Management as An Example
This project anticipates addressing the obesity epidemics problem which has caused unhealthy lifestyle in billions of obesities and overweight people worldwide.
- Conditions
- Weight Loss, Body Fat Rate Loss, Body Composition Change
- Trial name
- NCT06380920
- Testing
- "AI Mindful Eating" App, Outpatient regular follow-up
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Cheng-Kung University Hospital
Obesity Prevention, Weight Change
Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance
The purpose of this study is to find out what combination of components, if any, offers the best support for keeping weight off after someone loses weight.
- Conditions
- Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
- Trial name
- OPT-X (NCT06785064)
- Testing
- Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS)
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity, Weight Change, Body
Linking Temporal Patterns of Modifiable Behaviors to Weight Loss Outcomes
This study is designed as an observational trial. The objective of this study is to follow-up with participants 3 years after completion of an 18-month comprehensive behavioral weight loss intervention.
- Trial name
- NCT03840733
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A
The purpose of the study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03470558
- Testing
- Dietary habits
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Brigham and Women's Hospital
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C
The purpose of the study is to test how dietary habit interventions affect patients weight loss outcomes after bariatric surgery.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03482986
- Testing
- Dietary habits plan
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury
A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury
Acute Kidney Injury (AKI) is the sudden and recent reduction in kidney function. This can be detected by measuring a rise in blood creatinine level or from a reduction in urine.
- Trial name
- NCT05538351
- Testing
- Body Composition Monitor (BCM)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Hertfordshire
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B
The purpose of the study is to compare dietary habits after bariatric surgery in patients with poor weight loss versus good weight loss outcomes.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03467906
- Testing
- In-laboratory assessment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Obesity
Collaborate2Lose: Involving Support Persons in Weight Management
This study involves an evaluation of whether social support from a cohabitating adult improves Veteran weight loss in a weight management program.
- Trial name
- NCT05448313
- Testing
- Dyadic intervention, Veteran-only intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Body Weight, Body Weight Changes
Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program
The purpose of this research study is to test the feasibility and acceptability of an interactive counselor -led online family skills training as part of a behavioral weight loss program for Black Adults.
- Conditions
- Body Weight, Body Weight Changes, Obesity, Overweight and Obesity
- Trial name
- TEAM+ (NCT05981508)
- Testing
- Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Change, Body
Healthy Homes/Healthy Families (HH/HF) Intervention in 2-1-1 Callers
This trial will evaluate a healthy eating and weight gain prevention intervention for delivery through calls to the 2-1-1 number.
- Trial name
- NCT04373434
- Testing
- Health Homes/Healthy Families (HH/HF) Intervention, Control
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Emory University
Weight Change, Body, Obesity
Digital Health Weight Management Among Public Housing Residents
This research will test the efficacy of a weight management intervention through a three-group randomized trial: mHealth only, mHealth+Community Health Worker (CHW) support, versus control group, among residents of Boston's…
- Trial name
- NCT04852042
- Testing
- mHealth, CHW support
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Tufts Medical Center
Post Partum, Breast Feeding
The Effect of WhatsApp-Based Education and Counseling on Breastfeeding Self-Efficacy, Body Satisfaction, Healthy Lifestyle Behaviors, and Weight Retention in Postpartum Women: A Randomized Controlled Trial
Brief Summary: This randomized controlled trial aimed to evaluate the effect of WhatsApp-based education and counseling on breastfeeding self-efficacy, body satisfaction, healthy lifestyle behaviors, and weight retention in…
- Conditions
- Post Partum, Breast Feeding, Body Image, Health Behavior
- Trial name
- NCT07185906
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Inonu University
Weight Change
Wearable-Supported Exercise to Reduce Postpartum Weight
The aim of this study is to examine the effect of walking exercise in postpartum women and to evaluate the weight management intervention by using step tracker. The following hypotheses will be tested: 1.
- Trial name
- NCT07153081
- Testing
- Actigraphy watch intervention
- Where
- Singapore
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Overweight, Nutrition Disorder, Child
Fit Child - Clinical Study on Weight Control
Children with abnormal weight development of BMI will be given either placebo or a probiotic protein formula and measures of weigh gain during a 3-mont treatment will be conducted
- Conditions
- Overweight, Nutrition Disorder, Child, Weight Change, Body
- Trial name
- FITCHI (NCT03196453)
- Testing
- Probiotic
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity
ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)
Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss…
- Trial name
- NCT06174389
- Testing
- Behavioral Weight Loss Program
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Washington
Metabolic Syndrome, Lipid Profile
Gluten Free Diet on Metabolic Syndrome
This study benefits the community by highlighting the potential of a gluten-free diet as a non-pharmacological, effective approach to managing obesity and type 2 diabetes.
- Conditions
- Metabolic Syndrome, Lipid Profile, HOMA-IR, Weight Change, Body
- Trial name
- NCT07127055
- Testing
- No intervention, gluten free diet
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- University of Lahore
Brief Intervention
The Effect of a Brief Intervention on Behavıoral Change, Anthropometric and Metabolic Variables
This study will evaluate the effect of a brief intervention on anthropometric and metabolic changes in overweight women with low health literacy. The total number of samples was determined as 88.
- Trial name
- NCT05978323
- Testing
- Brief intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Mersin University