Clinical trials: Weight Changes, Body
Obesity
Supporting Decisions on Lifestyle Change
This study will test the effects of a brief, individually tailored intervention aiming to increase initiation of comprehensive behavioral weight loss treatment on weight.
- Trial name
- NCT06206954
- Testing
- MyHealthPath Tool, MyHealthPath Guide
- Where
- United States
- Volunteers
- 864 people
- Sponsor
- University of Florida
Cognitive Change
Exercise in Older Adults at Risk for Type 2 Diabetes
Older adults with type 2 diabetes experience neurocognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (i.e., those who are overweight and/or…
- Trial name
- NCT05229705
- Testing
- Resistance exercise
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Morbid Obesity, Type2 Diabetes
Elucidating the Mechanism of Remission of Type 2 Diabetes in Morbid Obese Patients After Bariatric Surgery
The main aim of this study is to elucidate the mechanism of the remission of type 2 diabetes in the morbid obese patients after laparoscopic sleeve gastrectomy.
- Trial name
- NCT03038373
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Kidney Transplantation
Change of Body Composition After Kidney Transplantation in Korea
The graft survival in kidney transplantation has been improving after the introduction of new immunosuppressive agents. Therefore, other complications after transplantation are concerned; one of those is obesity.
- Trial name
- NCT01157884
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Obesity
Improving Weight Loss Maintenance Through Alternative Schedules of Treatment
This project examines the effects of differing schedules of extended care contact following weight loss treatment in order to prevent weight regain following treatment.
- Trial name
- ImWeL (NCT02487121)
- Testing
- variable interval schedule, self-directed treatment
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dementia, Alzheimer Type, Weight Loss
Partners at Meals - Respite Care and Home (PAM)
The goal of this study was to test the efficacy of a mealtime intervention in respite care centers for people with dementia and their caregivers.
- Trial name
- PAM (NCT03622814)
- Testing
- Partners at Meals, Enhanced Usual Condition
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Hypertension, Obesity
Observational Non-interventional Study (Anwendungsbeobachtung) With Telmisartan in High-risk Hypertensives
This observational non-interventional study will assess (under conditions of clinical practice in daily routine) the antihypertensive efficacy of telmisartan treatment with or without active promotion of lifestyle changes in…
- Trial name
- NCT00539487
- Where
- 2,389 sites in Germany
- Volunteers
- 5,827 people
- Sponsor
- Boehringer Ingelheim
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Bariatric Surgery Candidate
Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery
Currently, a ketosis-inducing programme, usually a liquid meal replacement, is the standard of care for pre-operative dietary management.
- Trial name
- NCT06461247
- Testing
- Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals, Standard Care Group
- Where
- 2 sites in Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Colorectal Cancer, Liver Metastasis Colon Cancer
The CLiFF Study: Change in Liver Function and Fat in Pre-operative Chemotherapy for Colorectal Liver Metastases
The CLiFF Study will assess changes in liver function and liver fat in patients with colorectal liver metastases (CLM) undergoing pre-operative chemotherapy before liver resection.
- Conditions
- Colorectal Cancer, Liver Metastasis Colon Cancer, Chemotherapy Effect, Obesity
- Trial name
- CLiFF (NCT03562234)
- Testing
- MR, LiMAx
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Manchester
Obesity
Endoscopic Sleeve Gastroplasty for Moderate Obesity
Weight loss is of paramount importance to ameliorate obesity-related complications. Endoscopic sleeve gastroplasty is a new therapeutic option to obtain significant weight reduction in obese patients.
- Trial name
- PLICATURE (NCT05750134)
- Testing
- OBPLUS Clinical Database : data analysis, Biological collection "Liver, bile ducts and pancreas": sample analysis
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Overweight
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program.
- Trial name
- SURMOUNT-3 (NCT04657016)
- Testing
- Tirzepatide
- Where
- 65 sites in United States, Argentina and 2 more
- Volunteers
- 579 people
- Sponsor
- Eli Lilly and Company
Obesity
STAGES Trial: Study of Adiposity, Growth and Endocrine Stages
The investigators propose to conduct a cross-sectional study of 60 participants who are 18-30 years of age to undergo research PET/CT.
- Trial name
- STAGES (NCT01460784)
- Where
- United States
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Frailty
Weight Loss and Exercise in Physically Limited Obese Elderly Subjects
The overall purpose of this research is to determine the effect of weight loss and physical training on quality of life, physical function, metabolism, bone strength, body fat and muscle mass.
- Conditions
- Obesity, Frailty, Elderly
- Trial name
- NCT00146133
- Testing
- diet, exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Anorexia, Cachexia
Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer
RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss caused by cancer.
- Conditions
- Anorexia, Cachexia, Head and Neck Cancer, Quality of Life
- Trial name
- NCT00006799
- Testing
- megestrol acetate, quality-of-life assessment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Bariatric Surgery, Pregnency
Mother and Offspring's Nutritional Status -Pregnancy After Maternal Bariatric Surgery
The goal of this observational study is to learn how bariatric surgery affects the health and nutritional status of women and their babies during pregnancy and after birth.
- Conditions
- Bariatric Surgery, Pregnency, Reproductive Health and Childbirth, Pregnancy and Delivery
- Trial name
- MOBS (NCT07877233)
- Testing
- Post-Bariatric Maternal and Infant Health Study, Observation arm
- Where
- 3 sites in Norway
- Volunteers
- 210 people
- Sponsor
- Helse Nord-Trøndelag HF
Obesity, Bariatric Surgery Candidate
The Collateral Impact of Bariatric Surgery on Families
This proposal is designed to examine the impact of bariatric surgery on the health of patients and their families. The shared environment of spouses/cohabitating partners suggests that patients' families are exposed to the…
- Conditions
- Obesity, Bariatric Surgery Candidate, Weight Loss
- Trial name
- Collateral (NCT02021630)
- Testing
- Outcomes
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Geisinger Clinic
Metabolic Syndrome, Weight Loss
Link Between Biochemical, Anthropometric Variables and CD36 in Metabolic Syndrome After a Low-calorie Diet
This study evaluated the effects of a weight loss diet on biochemical, anthropometric variables, and cluster of differentiation 36 (CD36) levels in 65 patients newly diagnosed with metabolic syndrome (MetS).
- Trial name
- NCT06881706
- Testing
- medical nutrition therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ordu University
Obesity
Weight Loss in Obese Children and Adolescents and Its Effect on Improvement of Destructive Changes in Blood Vessels
Obesity in children and adolescents is associated with morphologic and functional changes of the vascular wall, suggesting a potential role of juvenile obesity for the development of atherosclerosis later in life.
- Trial name
- NCT00439933
- Testing
- low fat and polysaccharide rich diet, specific physical training program for obese children
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Health Promotion, Obesity
Study of a Learning Collaborative to Implement Health Promotion in Mental Health
Healthcare organizations have increasingly formed quality-improvement Learning Collaboratives to improve care for specific populations; however, there are few data on the effectiveness of this strategy compared to conventional…
- Conditions
- Health Promotion, Obesity, Organizational Innovation, Mental Health Services
- Trial name
- NCT03891368
- Testing
- Virtual Learning Collaborative, Technical Assistance
- Volunteers
- 55 people
- Sponsor
- Massachusetts General Hospital
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