Clinical trials: Weight Changes, Body
Weight Loss
Belviq Tablet® Post Marketing Surveillance Protocol
Post-marketing surveillance of Lorcaserin
- Trial name
- NCT03741010
- Volunteers
- 3,000 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Obesity, Weight Loss
Mechanistic Insights to Weight Loss Maintenance Through SGLT2 Inhibitors
Obesity increases the risk of cardiometabolic diseases such as hypertension and diabetes. Weight loss interventions such as low-calorie diet and physical activity are effective for weight loss in the short term, but weight loss…
- Trial name
- NCT05885074
- Testing
- Empagliflozin Arm, Control Arm, Exercise capacity VO2 maximum determination
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Evaluation of the Shape Up Rhode Island Campaign Study 5
Obesity is a major health problem that has reached epidemic levels. Efforts are needed to develop cost-effective public health approaches for weight loss and maintenance.
- Trial name
- NCT00948415
- Testing
- Evaluation of the Shape Up RI Campaign
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity (Disorder)
JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity
The Joule MARS study is a single center, randomized, open label clinical trial aiming to explore the metabolic adaptations that occur in response to weight management in adolescents with obesity.
- Trial name
- JOULE-MARS (NCT06852391)
- Testing
- Semaglutide Pen Injector, Behavioural Lifestyle Program (BLP)
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- McMaster University
Weight Gain
Investigating the Feasibility and Preliminary Effects of Yoga on Excessive Gestational Weight Gain
This study will test the feasibility (i.e., acceptability, demand) of a 12-week prenatal yoga intervention on excessive gestational weight gain (GWG) in pregnant women in the second trimester (enrolled at 12-24 weeks).
- Trial name
- NCT03893708
- Testing
- Prenatal yoga, Pregnancy education
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obese, Normal Body Weight
Cold Induced Changes in White Adipose
An adaptation to a cold environment is a tendency to generate heat within our body. Some of this heat comes from our fat tissue.
- Conditions
- Obese, Normal Body Weight, Prediabetes, Metabolic Syndrome
- Trial name
- NCT02596776
- Testing
- Fat biopsy, Propranolol and fat biopsy, heavy water and fat biopsy
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Philip Kern
Alcohol Drinking, Weight Loss
The Effects of Alcohol Consumption on Central Adiposity
The objective of the proposed study is to enroll women with obesity that will undergo a controlled, energy restricted feeding intervention to test the effects of chronic ethanol consumption on adipose distribution and circulating…
- Conditions
- Alcohol Drinking, Weight Loss, Adiposity, Obesity
- Trial name
- CONSUME (NCT03521817)
- Testing
- Alcohol, No Alcohol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Approaches for Improving Long-term Weight Loss
The purpose of this study is to examine two approaches for improving long-term weight loss success. All participants will receive a 12-week, in-person standard behavioral weight loss program followed by either 12 weeks of yoga…
- Trial name
- NCT03799289
- Testing
- Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity
Effect of Weight Loss and Lifestyle Changes on Vascular Inflammatory Markers in Obese Women
Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue.
- Trial name
- NCT00666874
- Testing
- lifestyle changes, Control - general information
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Nutritional Deterioration, Malignant Solid Tumor
Benefits of Nutritional Supplement in Cancer Care
This is an exploratory, open-label, 2:1 randomized controlled trial conducted across collaborating oncology clinics and extended research networks in Hong Kong.
- Conditions
- Nutritional Deterioration, Malignant Solid Tumor, Cancer Cachexia, Cancer Malnutrition
- Trial name
- NCT07869290
- Testing
- Nutrition supplement, Digital Health App Monitoring, Individualized Dietitian Consultation
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Obesity
ENGAGED: E-Networks Guiding Adherence to Goals for Exercise and Diet
The ENGAGED study is a 12-month randomized controlled trial investigating different strategies to improve weight loss in overweight individuals.
- Trial name
- ENGAGED (NCT01051713)
- Testing
- Technology Supported, Standard
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Esophageal Neoplasms, Stomach Neoplasms
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Improvements to treatment strategies for patients upper gastrointestinal cancers have produced an increasing population of people who remain free from disease recurrence in the long term.
- Conditions
- Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition
- Trial name
- NCT02385617
- Testing
- Octreotide
- Where
- 2 sites in Ireland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Pancreatic Cancer, Cachexia
Study of Onivyde and 5-FU in Combination With Xilonix for Pancreatic Cancer With Cachexia
This study is being conducted to examine the safety of the investigational drug, Xilonix(™), in addition to standard doses of Onivyde® (nanoliposomal irinotecan) and 5- fluorouracil (5FU)/folinic acid (leucovorin) for pancreatic…
- Conditions
- Pancreatic Cancer, Cachexia, Weight Loss
- Trial name
- OnFX (NCT03207724)
- Testing
- Xilonix plus Onivyde and 5FU
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Andrew Hendifar, MD
Weight Change, BMI
Childhood Obesity Prevention Project in Gran Canaria
Given the alarming rates of obesity and overweight in our child population, the investigators have developed an intervention strategy, based on a multidisciplinary, school-centered approach, which addresses nutritional education…
- Conditions
- Weight Change, BMI, Activity Level, Cholesterol (total and HDL)
- Trial name
- POI (NCT06607159)
- Testing
- Implementation of healthy habits teaching protocol
- Where
- Spain
- Volunteers
- 557 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Universitario Insular Materno Infantil
Weight Loss, Weight Gain
Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight
The primary objective of this study is to determine to what extent provision with RUTF will promote catch up growth in children following an acute uncomplicated episode of P. falciparum malaria.
- Conditions
- Weight Loss, Weight Gain, Convalescence, Malaria
- Trial name
- NCT00819858
- Testing
- RUTF (Plumpynut®)
- Where
- Republic of the Congo
- Volunteers
- 180 people
- Sponsor
- Medecins Sans Frontieres, Netherlands
Obesity
Study to Promote Weight Loss in Primary Care Practices
The purpose of this study is to determine if primary care based, telephone-delivered weight loss interventions are effective.
- Trial name
- NCT00749606
- Testing
- Individual telephone intervention, Group telephone intervention
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Metabolic Complications
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
We hypothesize that metformin co-administered with olanzapine will be well tolerated and associated with significantly less insulin resistance, weight gain and dyslipidemia as compared to olanzapine plus placebo.
- Trial name
- NCT00682448
- Testing
- Metformin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rush University Medical Center
Non-small Cell Lung Cancer, Pancreatic Cancer
Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15
Study to evaluate the efficacy, safety and tolerability of ponsegromab compared to placebo in patients with cancer, cachexia, and elevated GDF 15.
- Conditions
- Non-small Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Loss of Appetite
- Trial name
- PROACC-1 (NCT05546476)
- Testing
- ponsegromab
- Where
- 78 sites in United States, Australia and 9 more
- Volunteers
- 187 people
- Sponsor
- Pfizer
Obesity, Weight Gain
Evaluation of the Efficacy of the Watch Your Weight During Holidays Program for the Prevention of Body Weight Gain in Mexican Adults.
Obesity is the main risk factor for the development of chronic-degenerative diseases in Mexico. Due to the difficulty of treating obesity, prevention is urgently needed.
- Conditions
- Obesity, Weight Gain, Overweight
- Trial name
- NCT05580926
- Testing
- Watch your Weight During Holidays, Control Group (minimal intervention)
- Where
- Mexico
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rolando Giovanni Díaz Zavala
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