Clinical trials: Weight Changes, Body
Anorexia, Cachexia
Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Infliximab may improve cancer-related weight loss, lack of appetite, and fatigue.
- Conditions
- Anorexia, Cachexia, Fatigue, Lung Cancer
- Trial name
- NCT00040885
- Testing
- infliximab, docetaxel
- Where
- 188 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Weight Loss
VK2735 for Weight Management Phase 2 (Venture Oral Dosing)
This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm dose-finding study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of VK2735…
- Trial name
- NCT06828055
- Testing
- VK2735
- Where
- 15 sites in United States
- Volunteers
- 280 people
- Sponsor
- Viking Therapeutics, Inc.
Lower Extremity Amputation
Weight Loss Intervention for Individuals With Lower Extremity Amputation
The purpose of this study is to pilot test a program to help overweight and obese individuals with a lower extremity amputation (LEA) lose weight and become more physically active.
- Trial name
- MOVE-LEAP (NCT02085785)
- Testing
- Coached group, Self-directed control group, Screened only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Obesity Prevention, Healthy
Validation of Energy Expenditure Measures Study
The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance.
- Trial name
- ValEE (NCT07155564)
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- University of Leipzig
Loss-of-control Eating, Obesity/Overweight
Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)
This study will test the effectiveness of lisdexamfetamine medication as a treatment for loss-of-control eating and weight following bariatric surgery.
- Trial name
- NCT04599504
- Testing
- Lisdexamfetamine Dimesylate (Medication)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Obesity, Weight Loss
ReShape Vest™ for the Treatment of Obesity (Europe)
To assess the safety and effectiveness of the LGV in treating obese subjects with a BMI of 35 kg/m2 to 55 kg/m2 who have failed one or more conservative weight-reduction alternative(s), such as supervised diet, exercise, and…
- Trial name
- NCT03918564
- Testing
- Laparoscopic Gastric Vest (LGV)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- ReShape Lifesciences
Obesity & Overweight, Weight Loss
A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change
This prospective cohort study collected baseline data and followed up obese patients at their first visit to a weight loss clinic.
- Conditions
- Obesity & Overweight, Weight Loss, Metabolic Syndrome, Metabolic Dysfunction-Associated Steatohepatitis
- Trial name
- NCT07239167
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Obesity, Insulin Resistance
Glycemic Load, Metabolism & Obesity in Pregnancy
The purpose of the study is to determine if a low glycemic load diet reduces the gain of body fat and insulin resistance during the last half of pregnancy in obese women.
- Trial name
- PANS (NCT01287299)
- Testing
- Low Glycemic Load diet, Low Fat Diet
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Weight Loss, Weight, Body
Sleep Goal-focused Online Access to Lifestyle Support
The overall goal of the study is to develop a novel weight loss intervention for postpartum people by providing strategies to improve sleep, diet, and physical activity behaviors.
- Trial name
- SGOALS (NCT05942326)
- Testing
- Sleep GOALS, Education
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Lung Cancer, Pancreatic Cancer
Nutritional Problems in Pallative Cancer
The aim of this study is to investigate those nutritional problems contributing to loss of lean body mass in lung and pancreas cancer patients in chemotherapy.
- Trial name
- NCT04846985
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Jens Rikardt Andersen
Bariatric Surgery, Morbid Obesity
The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery
Bariatric guidelines recommend preoperative weight loss of 5% to reduce the risk of surgical complications. However, results in the literature on the improvement of surgical procedure and outcomes are still conflicting.
- Trial name
- NCT04433338
- Testing
- 14-day Low Calorie Diet
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Rijnstate Hospital
Weight, Blood Pressure
Interactive Web Program and Health Coaching for Prehypertensive Adults
This project will develop and evaluate an interactive blood pressure self-management program for adults with prehypertension. The program will target blood pressure self-monitoring and the five proven lifestyle modifications…
- Trial name
- Prehype (NCT02637063)
- Testing
- BlipHub mobile-web app, BlipHub mobile-web app + health coaching, Usual care
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Oregon Center for Applied Science, Inc.
Obesity
A Study to Examine the Long Term Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjects
This is a long term extension to study 137OB-201 which is designed to examine the effect of pramlintide on body weight and its safety and tolerability in obese subjects.
- Trial name
- NCT00189514
- Testing
- pramlintide acetate
- Where
- 21 sites in United States
- Volunteers
- 210 people
- Sponsor
- AstraZeneca
Weight Loss, Postpartum Weight Retention
Weight Loss and Physical Fitness Following Pregnancy in Active Duty Women
Pregnancy and delivery are major stressors on the female body and contribute significantly to permanent weight gain and associated morbidity in women.
- Trial name
- PADaWL (NCT05518604)
- Testing
- Counseling with goal of modifying eating behaviors
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tripler Army Medical Center
Cancer, Cachexia
Resting Energy Expenditure in Palliative Cancer Patients
The study purpose is to measure REE by indirect calorimetry and to determine limits of agreement with confidence intervals between measured REE and predictive equations for determination of energy requirements in patients with…
- Trial name
- REPAT (NCT06206785)
- Where
- Norway
- Volunteers
- 160 people
- Sponsor
- Norwegian University of Science and Technology
Weight Loss, Obesity
The Effect of Branched-Chain Amino Acid Supplementation and Exercise on Body Composition During Energy Restriction
This double blind placebo study will take place over an 8 week treatment period of diet and exercise. All participants (n=16), in two groups, will be placed on the same hypocaloric diet and exercise program.
- Trial name
- NCT02630238
- Testing
- Branched-Chain Amino Acid Supplementation, Exercise, Diet
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Body Weight Changes
Variation in Body Composition on the Fate of Older Subjects During SSR Hospitalization
The aim of this study is to correlate weight variation as well as body composition with mortality and unscheduled readmission of geriatric population
- Trial name
- VALCOR (NCT04464278)
- Volunteers
- 360 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nasopharyngeal Cancinoma (NPC)
Prophylactic Nanocrystalline Megestrol Acetate Versus Placebo for Chemoradiotherapy-Related Anorexia in Nasopharyngeal Carcinoma
This phase III randomized, double-blind, placebo-controlled trial evaluates whether nanocrystalline megestrol acetate can reduce anorexia in patients with locally advanced nasopharyngeal carcinoma (NPC) undergoing concurrent…
- Trial name
- NCT07796789
- Testing
- Nanocrystalline Megestrol Acetate Oral Suspension
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Sun Yat-sen University
Schizophrenia
Melatonin for Prevention of Metabolic Side Effects of Olanzapine
The purpose of this study is to determine whether melatonin can prevent metabolic side effects of olanzapine such as weight gain, elevated glucose concentrations and lipid abnormalities.
- Trial name
- NCT01593774
- Testing
- Melatonin
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Guilan University of Medical Sciences
Weight Change, Body
Microbiome and Bariatric Surgery
This is a prospective, 24-month, longitudinal study of patients planning to undergo bariatric surgery (Roux-en-Y Gastric Bypass or Sleeve Gastrectomy) in which we aim to identify correlates and predictors of observed weight loss…
- Trial name
- Biobehavioral (NCT03065426)
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- North Dakota State University
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