Clinical trials: Weight Changes, Body
Heart Failure, Overweight and Obesity
Mobile Applet for Weight Management in Obese Heart Failure Patients
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart…
- Conditions
- Heart Failure, Overweight and Obesity, Weight Loss, Heart Failure With Reduced Ejection Fraction
- Trial name
- IDEAL-HF (NCT06455878)
- Testing
- Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scale
- Where
- 26 sites in China
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Heart Health Research Center
Body Weight Changes, Overweight
Lifestyle Education for Activity and Nutrition for a Leaner You
Although weight loss programs are effective in the short-term, maintaining weight loss is more challenging. Regularly tracking and logging physical activity (PA) and diet is related to greater improvements in PA and diet and to…
- Trial name
- LEAN (NCT00957008)
- Testing
- Group weight loss program, Group weight loss program plus use of the Senseware Armband, Use of the senseware armband alone program
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Diabetes, Heart Diseases
PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Foods in the human diet can affect the development of diseases over time, such as diabetes or heart disease. This is because the amount and types of foods in the diet eat can affect a person's weight, and because different foods…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT03983733
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Neoplasms, Cancer
Multimodal Program for Cancer Related Cachexia Prevention
The aim of the study is to evaluate the effectiveness of a multifactorial education and support program for the prevention of cancer-related cachexia syndrome, for patients and their family caregivers during anti-cancer treatment.
- Conditions
- Neoplasms, Cancer, Cachexia, Malnutrition
- Trial name
- NCT04627376
- Testing
- Multimodal education and support program for cancer related cachexia prevention
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- Cyprus University of Technology
Pre Diabetes, Insulin Resistance
Exenatide and Weight Loss for Diabetes Prevention
Exenatide, a GLP-1 agonist approved for lowering blood glucose concentrations in patients with type 2 diabetes, has been associated with restoration of the first-phase insulin response when administered intravenously to patients…
- Trial name
- NCT02084654
- Testing
- Exenatide 5 and 10 mcg 2 times a day
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Weight Gain, Weight Loss
Nutritional Responses to Acute Exercise Performed on the LipoxMax in Obese Adolescents
Primarily over the past 20 years, it has been shown that physical activity not only leads to energy expenditure but can also indirectly influence energy intake and feelings of hunger in both lean and obese adults, suggesting that…
- Conditions
- Weight Gain, Weight Loss, Eating Attitudes, Obese Adolescents
- Trial name
- LipoxAPP (NCT07844330)
- Testing
- The participants in this study are adolescents with obesity (with a Body Mass Index above the 95th percentile on international growth charts)
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Emile Roux
Pompe Disease, Muscle Loss
Nutritional Therapy in Late-onset Pompe Disease
RATIONALE: Pompe disease (PD) is a recessive genetic disorder wherein the body cannot break down glycogen due to a mutation in the acid alpha glucosidase (GAA) gene, which encodes for acid alpha-glucosidase.
- Conditions
- Pompe Disease, Muscle Loss, Obesity, Nutrition Poor
- Trial name
- PDT-MIS (NCT06130228)
- Testing
- Multi-ingredient supplement (PDT-MIS)
- Volunteers
- 28 people
- Sponsor
- McMaster University
Chronic Diseases, Obesity
Home-Based Exercise and Weight Control Program for Pain Control in Overweight Elderly With Osteoarthritis of the Knee
The purpose of this study is to determine whether a home-based exercise and weight control program applied to elderly overweight individuals with painful osteoarthritis of the knee, would result in pain reduction.
- Conditions
- Chronic Diseases, Obesity, Osteoarthritis, Pain
- Trial name
- NCT00126737
- Testing
- Weight Control Nutritional Program, Home-based exercise program
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- US Department of Veterans Affairs
Obesity
Efficacy of Polyglucosamine Long Term Treatment
The polyglucosamine, specification L112, is a medical device and in this clinical trial used for weight reduction in moderately obese participants following a long term treatment lasting 12 months.
- Trial name
- NCT02682277
- Testing
- polygucosamine
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
Overweight and Obesity
Could a Time-restricted Diet Compete With a Calorie-restricted 6-meal Diet?
The prevalence of obesity and obesity-related diseases are on the rise worldwide. The widely accepted approach in dietary treatment of obesity is the calorie-restricted three meals-three snacks a day diet; however, alternative…
- Trial name
- NCT06364475
- Testing
- 16:8 Time-Restricted Intermittent Fasting Group, Energy-Restricted Six-Meal Group
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
PreDiabetes
Multidisciplinary Care for Lifestyle Change for Metabolic Control and Quality of Life in Prediabetes (PreCPro)
Prediabetes is part of the natural history of type 2 diabetes mellitus, which is one of the main causes of morbidity and mortality in Mexico.
- Trial name
- PreCPro (NCT06468553)
- Testing
- Prediabetes Care Program
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Clinica Especializada en el Manejo de la Diabetes en la Ciudad de Mexico
Obesity, Bariatric Surgery
Analysis of Changes in Eating Habits on Post Bariatric Surgery Patients and Their Family Members
The main objective of this study is to identify changes in eating behaviors and physical activity in patients after bariatric surgery and their family members living in same household: children aged between 11-17 years, spouse…
- Trial name
- SOCIOB (NCT02431195)
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Weight Loss
Helping Employees Lose Pounds
This study will evaluate the effectiveness of financial incentives and messaging tailored to individual goals and aspirations to promote and sustain weight loss.
- Trial name
- HELP (NCT02853877)
- Testing
- Weekly Incentive
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Michigan
Obesity, Insulin Resistance
Probiotics on Body Composition and Insulin Resistance in Patients With Obesity and Its Association With Gut Microbiota
This study aims to evaluate the modifications in body composition and insulin resistance state in patients with grade II and III obesity included in an interventional lifestyle changes program and treated with probiotics (1 x…
- Conditions
- Obesity, Insulin Resistance, Microbial Colonization
- Trial name
- NCT04086173
- Testing
- Probiotics
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Overweight, Obesity
Effect of GSP3 on Body Weight in Overweight and Obese Subjects
The FLOW (First Loss Of Weight) study is designed to assess the effects of repeated administration of GSP3, an investigational product, on body weight.
- Trial name
- FLOW (NCT03008954)
- Testing
- GSP3, Avicel (modified Cellulose)
- Where
- 5 sites in Czechia, Denmark and 1 more
- Volunteers
- 128 people
- Sponsor
- Gelesis, Inc.
Hemodialysis
Bioimpedance Spectroscopy (BIS): Fluid Changes in Hemodialysis Patients
In connection with dialysis treatment, fluid and salt balance changes. Some kidney disease patients experience fluid accumulation in the body and need to have excess fluid removed via the dialysis machine.
- Trial name
- NCT07803029
- Testing
- Bioimpedance analysis
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Per Ivarsen
Obesity, Abdominal, Adiposity
Transcriptional Changes in Isolated Human Adipocytes During Obesity
Adipocytes play an important role in our body through their function as metabolic energy stores in the form of fat deposits, which are stored when metabolic energy is in excess and released when energy levels are low.
- Trial name
- NCT06907212
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Advanced Heart Failure, Cardiac Cachexia
Cardiac Cachexia in Advanced Heart Failure
Heart failure is a condition in which the heart stops pumping effectively, causing symptoms such as breathlessness or leg swelling. It affects around 900,000 people in the United Kingdom.
- Conditions
- Advanced Heart Failure, Cardiac Cachexia, Weight Loss
- Trial name
- CACH-IT-AHF (NCT06259045)
- Where
- United Kingdom
- Volunteers
- 261 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Weight Loss, Insulin Resistance
Comparison of Different Weight Loss Diets With Different Protein Content
High-protein diets better preserve lean mass than conventional low-fat diets. However, they are costly and have potential health risks.
- Trial name
- NCT02277275
- Testing
- BCAA
- Where
- Singapore
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Overweight, Obesity
ACTION PAC: Adolescents Committed to Improvement of Nutrition & Physical Activity
Using a previously created weight management program for adolescents, the intervention will be implemented through school-based health centers (SBHC) and will be delivered by SBHC providers trained in Motivational Interviewing.
- Trial name
- ACTION PAC (NCT02502383)
- Testing
- ACTION PAC, Communication with parents
- Where
- United States
- Volunteers
- 991 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
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