Clinical trials: Weight Changes, Body
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pregnancy; Nutritional Diseases
Growth and Adiposity in Newborns: The Influence of Prenatal Docosahexaenoic Acid (DHA) Supplementation
The purpose of this study is to learn if participants in the ADORE study (NCT02626299), who took a DHA supplement during pregnancy, see favorable body fat in their infants from birth to 24 months, and if excessive or appropriate…
- Trial name
- ADORE-GAINS (NCT03310983)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Diabetes Mellitus, Bariatric Surgery Candidate
Paraoxonase and HDL Qualities in Glycaemia and Inflammation
The incidence of coronary heart disease (CHD) is significant in the super-obese and diabetics. Inflammation is believed to play an important part in the development of CHD, and the large collection of abdominal fat in the obese…
- Trial name
- PON1 (NCT02169518)
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Non-alcoholic Fatty Liver Disease
Prebiotic Fibre Supplementation and Gut Microbiota in Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a condition where accumulation of fat in the liver leads to metabolic dysfunction. Currently there are no approved treatments for NAFLD.
- Trial name
- NCT02568605
- Testing
- Prebiotic fibre, Weight Loss
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity
Optimal Timing of Exercise Initiation Within a Lifestyle Weight Loss Program
The primary aim of this study is to evaluate the extent to which an exercise intervention timed after diet-induced weight loss (rather than initiated at the same time) improves exercise adherence and long-term weight loss.
- Trial name
- NCT01985568
- Testing
- Sequential BT, Standard BT
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Weight Loss
Calories Counting Using an App for Weight Loss
This research aims to measure anew way of calories counting using a mobile app on weight loss and adherence to the mobile app. The participants should be adults who is overweight or obese and should have a smartphone with access…
- Trial name
- NCT04945291
- Testing
- New way of counting calories using the hands, Mobile applications
- Where
- Lebanon
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Overweight
Possibilities of Recording Changes in Various Health Parameters by Measuring Bioimpedance With the mBCA 555 During the Use of Products From the L112 Product Range
As a combination of medical products (mBCA scale, mBCA standing aid, length measuring rod and cloud-based software), the seca mBCA 555 makes it possible to determine nutritional status, energy consumption and body water…
- Trial name
- MEGA L112 (NCT07495696)
- Testing
- formoline L112 EXTRA
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
Obesity, Food Preferences
How Altered Gut-Brain-Axis Influences Food Choices: Part 1
Obesity is currently one of the most substantial health burdens. Due to the production of marked and sustained weight loss, bariatric surgery is an increasingly used therapeutic modality to combat obesity and its comorbidities.
- Trial name
- BrainFood (NCT04813003)
- Testing
- Functional Brain Imaging and neurobehavioural tasks
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lia Bally
Cachexia, Lung Cancer
Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
This study aims to identify if clarithromycin (CLM) has potential as a widely available and inexpensive treatment for cachexia (the loss of muscle mass) in people with non-small cell lung cancer (NSCLC).
- Trial name
- NCT02416570
- Testing
- Clarithromycin
- Volunteers
- 1 people
- Sponsor
- University of Nottingham
Obese, Obesity
Aleniglipron Phase 2 in Type 2 Diabetes Mellitus
The purpose of this study is to assess the safety and tolerability of aleniglipron at doses up to 180 mg once daily (QD) in participants with T2DM who are living with obesity (body mass index [BMI] ≥ 30 kg/m2) or overweight (BMI…
- Conditions
- Obese, Obesity, Obesity Type 2 Diabetes Mellitus, Weight Loss
- Trial name
- GSBR-1290 (NCT07400588)
- Testing
- Aleniglipron
- Where
- 16 sites in United States
- Volunteers
- 58 people
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Diabetes Mellitus Type 2 in Obese
Implementation of a Very Low Calorie Diet for Remission of Type 2 Diabetes in the Community
The complications associated with uncontrolled type-2 diabetes mellitus (T2DM) are numerous; reducing the quality of life for the patient and consuming a considerable portion of healthcare finances.
- Trial name
- NCT03536377
- Testing
- very low calorie liquid diet
- Where
- 4 sites in Barbados
- Volunteers
- 100 people
- Sponsor
- The University of The West Indies
Childhood Obesity
Husky Reads Effectiveness in Increasing Produce Preference and Food Group Identification in Preschool Children
Since 1998, UCONN undergraduate students have volunteered as part of a service- learning course to deliver a program called Husky Reads.
- Trial name
- NCT03338257
- Testing
- Husky Reads Intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- UConn Health
Obesity and Type 2 Diabetes
Investigating Metabolic and Psychological Adaptations in a Clinical Trial
This study aims to explore how food insecurity, a lack of consistent access to enough food, may lead to changes in the body that make it harder to lose weight.
- Trial name
- IMPACT (NCT06800794)
- Testing
- Behavioral Skill Training, Meal Provisioning
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- State University of New York at Buffalo
Weight Gain
Lorcaserin for Weight Loss Management in Patients on Antipsychotics: A Pilot Study
The purpose of this study is to determine whether lorcaserin is effective for weight reduction in patients with weight gain as a result of antipsychotic medications.
- Trial name
- NCT01962402
- Testing
- lorcaserin, Intensive dietary counseling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Southern California Institute for Research and Education
Diabetes Mellitus
Diabetes Resolution and Hormone Changes After BPDLL and LSG
To evaluate and compare prospectively the effects of Biliopancreatic Diversion Long Limb (BPDLL) and Laparoscopic Sleeve Gastrectomy (LSG) on resolution of diabetes mellitus type 2.
- Trial name
- NCT01481675
- Where
- 2 sites in Greece
- Volunteers
- 24 people
- Sponsor
- University of Patras
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Pregnancy, Weight Gain
Gestational Weight Gain and the Electronic Medical Record
Less than one third of pregnant women actually achieve the Institute of Medicine's (IOM) recommended weight gain. To date, there are no randomized controlled trials studying the use of the electronic medical record to alert…
- Trial name
- WATE (NCT01987141)
- Testing
- EMR Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Loyola University
Hypothermia
Effects of Heat and Moisture Exchanger in Combination With Air Forced Warming Blankets or Warming Intravenous Solutions on Intraoperative Hypothermia Prevention in Obese and Non Obese Patients During Intravenous Anesthesia
The aim of the present study was to evaluate if the combination of heat and moisture exchanger with air forced warming blankets or warming intravenous fluids prevents intraoperative hypothermia in obese and non obese women under…
- Trial name
- NCT01026766
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gestational Weight Gain, Overweight and Obesity
Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0
The goal of this clinical trial is to see if the enhanced HMZ 2.0 intervention with new control system/digital platform to regulate gestational weight gain (GWG) and impact maternal-infant outcomes while collecting implementation…
- Conditions
- Gestational Weight Gain, Overweight and Obesity, Pregnancy, Energy Balance
- Trial name
- HMZ Two (NCT05807594)
- Testing
- HMZ 2.0 Intervention, Attention Control Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Penn State University
Bipolar Disorder (BD)
Body Weight Changes After Switching to Lurasidone for Antipsychotic-induced Weight Gain in Bipolar Disorder
Study Objective: To evaluate the treatment effectiveness and safety by analyzing prescription patterns in a routine clinical practice setting and observing changes in clinical indicators (weight, BMI, HAM-D, CGI-S, CGI-I) among…
- Trial name
- NCT07834112
- Testing
- Lurasidone
- Where
- South Korea
- Volunteers
- 155 people
- Sponsor
- Dong-Wook Kim
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