Clinical trials: Weight Changes, Body
Cardiovascular Diseases, Coronary Disease
20 Year Changes in Fitness & Cardiovascular Disease Risk - Ancillary to CARDIA
To understand the complex, longitudinal relations between physical fitness, physical activity, body mass and composition and fat distribution, and genetic factors and their independent or interactive effects on the development of…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- NCT00106457
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Weight Loss
Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity.
- Trial name
- NCT06776081
- Testing
- Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Muscle Mass
Strength Training Response of Muscle in GLP-1 Users
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function.
- Trial name
- STRONG-GLP (NCT07104539)
- Testing
- Strength Training, Wait first, then strength training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Diabetes Mellitus, Type 2, Sarcopenia
Mediterranean Diet, Circuit Resistance Training, Empagliflozin in Elderly With Type 2 Diabetes: a Study Protocol
Primary objective: To assess the effects of a modified plant-based Mediterranean diet (vegeterranean diet), circuit resistance training (CRT) and empagliflozin alone or in combination on metabolic and physical function in elderly…
- Conditions
- Diabetes Mellitus, Type 2, Sarcopenia, Weight Loss
- Trial name
- NCT03560375
- Testing
- Circuit resistance training (CRT), Vegeterranean diet (V-Med diet), Empagliflozin 10 MG
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Weight Maintenance, Weight Loss
The SCULPT-Job Cohort Study
This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
- Conditions
- Weight Maintenance, Weight Loss, Stress, Psychological, Job Stress
- Trial name
- SCULPT-Job (NCT06965075)
- Testing
- Diabetes Prevention Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Obesity
Low Intensity Weight Loss for Young Adults
This is a 3-arm randomized controlled trial to test the efficacy of three novel motivational approaches to weight loss with 18-25 year olds.
- Trial name
- REACH (NCT02736981)
- Testing
- Behavioral Weight Loss (BWL), BWL + Autonomous Motivation, BWL + Extrinsic Motivation
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity, Overweight
HealthyTogether: RCT of a Dyadic Weight Management Intervention
Four in five Veterans have overweight or obesity. However, few eligible Veterans achieve meaningful weight loss in VA's national MOVE! Weight Management Program.
- Trial name
- NCT06619041
- Testing
- HealthyTogether
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-COVID Conditions, Obesity
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older…
- Trial name
- MARVEL (NCT05880108)
- Testing
- 12-weeks of Weight Loss, 12-weeks of Weight Stability
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Non-small Cell Lung Cancer (NSCLC), Small Cell Lung Cancer (SCLC)
Sarcopenia and Cachexia in Patients With Lung Cancer
The PHILICA study investigates whether muscle mass, muscle strength, and muscle function are associated with treatment tolerance, quality of life and survival in patients with lung cancer.
- Trial name
- PHILUCA (NCT06730685)
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Zealand University Hospital
Body Weight Changes
Prediction of Response to Bariatric Surgery in Patients With Severe Obesity
This is an retrospective and prospective (ambispective) study with data collection from volunteer patients who passed an MMPI-2-RF (Minnesota Multiphasic Personality Inventory-2-Restructured form) questionnaire in the…
- Trial name
- PREDI-CHIRBA (NCT06426290)
- Testing
- post-surgery psychological evaluation
- Where
- France
- Volunteers
- 360 people
- Sponsor
- Centre Hospitalier de Moulins Yzeure
Obesity
Health After Birth Intervention Trial
This trial is to assess the feasibility of a larger, definitive RCT and determine the clinical effectiveness of an NHS 1:1 programme versus a modified programme with a low carbohydrate dietary intervention (as per Feinman and…
- Trial name
- HABIT (NCT05137691)
- Testing
- Adapted NHS weight management 1:1 programme, NHS 1:1 weight management programme
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity, Smoking Cessation
A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
The purpose of this research study is to evaluate a multiple health behavior change intervention for weight loss and smoking cessation using medication (Naltrexone + Bupropion) and behavior therapy in adults seeking bariatric…
- Conditions
- Obesity, Smoking Cessation, Bariatric Surgery Patients
- Trial name
- NCT07398404
- Testing
- Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Medical University of South Carolina
Metabolic Syndrome, Obesity & Overweight
Evaluating the SWW Method Dietary Intervention for HbA1c and Weight Management as a Preventative Intervention in Women
This study evaluated the SWW Method®, a 12-week dietary and lifestyle intervention based on the carbohydrate-insulin model, in a healthy cohort of women aged 35-75.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Blood Glucose Monitoring, Type 2 Diabetes Prevention
- Trial name
- NCT07463417
- Testing
- SWW Method® Dietary and Lifestyle Intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Sarah Wragge Wellness
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Fecal Calprotectin Collection Protocol
The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study.
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease
- Trial name
- CALFE (NCT03143517)
- Testing
- Stool collection
- Where
- 13 sites in United States
- Volunteers
- 240 people
- Sponsor
- DiaSorin Inc.
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity, Diabetes
Time Restricted Feeding and Metabolic Rhythms
Current guidelines for the prevention and treatment of obesity focus on caloric restriction diets and increasing physical activity, but long-term compliance to these strategies is poor.
- Trial name
- Rhythm (NCT04009239)
- Testing
- Time Restricted Feeding
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
NSCLC Stage IV
Cachexia in NSCLC Patients: Diagnosis, Characterization, Prognosis, Functional and Skeletal Muscle Implications
LUCAX01 is a cohort study with patients with advanced NSCLC in tobacco users. in this study, patients will be submitted to baseline physical tests, blood and biopsy sample collection, and the main objective is to study the…
- Trial name
- LUCAX01 (NCT03960034)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Obesity, Morbid, Metabolic Syndrome
Non-randomized Prospective Comparison Between SASI Bipartition and RYGB
The main aim of this project is to assess the safety and efficiency of the SASI Bipartition.
- Conditions
- Obesity, Morbid, Metabolic Syndrome, Bariatric Surgery Candidate, Postoperative Complications
- Trial name
- NCT04469712
- Testing
- SASI Bipartition, Gastric bypass
- Where
- Norway
- Volunteers
- 280 people
- Sponsor
- Aleris Hospital
Obesity
The Safety and Efficacy of Low and High Carbohydrate Diets
This study will compare the safety and effectiveness of a low carbohydrate diet (Atkins Diet) with a high carbohydrate diet (conventional USDA diet).
- Trial name
- NCT00143936
- Testing
- Low- Carbohydrate -Atkins Diet, Low Calorie Diet
- Where
- 3 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Body Weight
Medifast 5 & 1 Plan
The purpose of this study is to compare the effectiveness of the Medifast 5 \& 1 Plan to a food-based, reduced-energy diet plan.
- Conditions
- Obesity, Body Weight, Weight Loss, Overweight
- Trial name
- NCT01211301
- Testing
- Food-based, Reduced Energy Diet Plan, Medifast 5 & 1 Plan
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
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