Clinical trials: Weight Changes, Body
Weight Loss
The Effect of Time Restricted Feeding on Fat Mass in Overweight Women
Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours.
- Trial name
- NCT02629900
- Testing
- Time restricted feeding
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Obesity, Overweight
Effectiveness of Online Visit Compared With In-person Clinic Visit on Weight Loss
Online visit and online counseling via telemedicine technology is a new service for obese people who wish to lose weight but because of their active lifestyle and time limitation cannot come to clinic.
- Trial name
- NCT03171961
- Testing
- online visit group, Clinic visit group, self-directed group
- Where
- 2 sites in Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Chronic Kidney Diseases, Diabetes Mellitus
Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study
This randomized controlled trail will evaluate the efficacy and safety of a simultaneous therapeutic carbohydrate restriction and treatment with the Sodium-Glucose-Transporter-2-Inhibitor dapagliflozin in comparison to the…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, PreDiabetes, Overweight and Obesity
- Trial name
- NCT06094231
- Testing
- Therapeutic carbohydrate restriction combined with an SGLT-2-Inhibitor
- Where
- Austria
- Volunteers
- 4 people
- Sponsor
- Department of Nephrology Clinic Ottakring Vienna
Muscle Loss, Obesity
Long-term Intervention Effects of a Personalized, Home-based Exercise Program and Nutritional Advice, Along With the Inclusion of a Pre-workout Multi-ingredient Supplement on the Body Composition, Functional Capacity and Quality of Life of Middle-aged and Older Adults (40-70 Years)
The purpose of this study is to analyse the potential benefits of ingesting a commercially available pre-workout multi-ingredient supplement providing ~90 Kcal.
- Conditions
- Muscle Loss, Obesity, Obesity, Abdominal, Weight Loss
- Trial name
- NCT04630977
- Testing
- Multi-ingredient Pre-workout supplement, Progressive Resistance Training, Nutritional Patterns Guideline
- Where
- United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Early Stage Breast Cancer
Percent Weight Change in the Medical Supplement Group of Early Breast Cancer
The goal of this RCT is to compare percent weight change in early breast cancer who takes medical supplement or not, during treatment with chemotherapy (standard AC regimen).
- Trial name
- NCT06311357
- Testing
- Ensure
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Obesity
Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
This research study is being performed to find out if a new device, AspireAssist Aspiration Therapy System, can help people with obesity to lose weight without causing too many side effects.
- Trial name
- PATHWAY (NCT01766037)
- Testing
- Aspiration Therapy (AspireAssist), Lifestyle Therapy
- Where
- 10 sites in United States
- Volunteers
- 171 people
- Sponsor
- Aspire Bariatrics, Inc.
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity in SNAP-Education
Childhood obesity prevention efforts are needed in the United States, especially for families with low income. Educating parents and caregivers on simple lifestyle and affordable home environment changes is an effective strategy…
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Child Behavior, Cognitive Change
- Trial name
- NCT05019339
- Testing
- Healthy HomeStyles, Eat Healthy Be Active
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
Our Year of Healthy Living (Formative Research & Intervention)
The purpose of this study is to evaluate the effect of a 7-month social marketing program - Healthy Me, Healthy We (previously called Our Year of Healthy Living) - in improving preschool children's (3-4 years) diet and physical…
- Trial name
- NCT02330354
- Testing
- Healthy Me, Healthy We
- Where
- United States
- Volunteers
- 2,293 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
Influence of Probiotic and Symbiotic in Body Weight, Blood Sugar and Lipemia of Obese Women
The purpose of this study is to evaluate whether gut microbiota modulation by probiotic and symbiotic contribute with weight loss and improvement of metabolic parameters in women with obesity.
- Trial name
- NCT02505854
- Testing
- Probiotic, Symbiotic
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Obesity, Periodontitis
Periodontal Inflammation and Epigenetics in Obese Individuals
The goal of this study is to investigate the long-term changes in host epigenetic modifications in obese individuals with periodontitis.
- Trial name
- NCT07610902
- Testing
- Non-surgical periodontal therapy will be administered
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Overweight and Obesity
An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents
The goal of this clinical trial is to learn about cardiovascular disease risk among adolescent girls with overweight/obesity. The main questions this trial aims to answer are: 1.
- Trial name
- NCT06147973
- Testing
- Acceptance-based Treatment (ABT), Health Education (HE) Comparison
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Obesity, Body Weight Changes
Prevention of Weight Gain
The purpose of this study is to test methods for preventing weight gain in normal-weight and overweight women aged 25 through 44.
- Trial name
- NCT00011102
- Testing
- Weight Gain Prevention for Women Project
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cachexia
Non-Invasive Assessment of Skeletal Muscle Loss in Cancer Patients - Phase II
The overall aim of this research is to develop a non-invasive approach to evaluate the production of 3-methylhistidine (3MH)in cancer patients, as a potential means of determining which patients are at high risk for future…
- Trial name
- 3MH-2 (NCT01694602)
- Testing
- (non-radioactive) Oral deuterated 3-methylhistidine (D-3MH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity & Overweight
Changes in Body Composition Including Muscle With Anti-Obesity Medications, Both With and Without Exercise
The goal of this clinical trial is to learn whether adding either cardiovascular exercise or resistance exercise to pharmacotherapy treatment for obesity improves the retention of lean mass compared to pharmacotherapy alone in…
- Trial name
- M3-E (NCT07698145)
- Testing
- Standard Medical Care with an Obesity Management Medication, Cardiovascular Exercise Training, Resistance Exercise Training
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Kansas Medical Center
Exocrine Pancreatic Insufficiency, Weight Gain
Role of Pancreatic Exocrine Secretion in Weight Gain After Pancreas Transplantation
Pancreas transplantation is currently the most reliable method for glycemic control in insulin dependent diabetic patients. Outcomes of pancreas transplantation have improved significantly over the years due to improved surgical…
- Trial name
- NCT04690738
- Testing
- Fecal Elastase Concentration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rush University Medical Center
Weight Loss, Pediatric Obesity
A Coordinated Parent/Child Dyad Weight Loss Intervention: Dyad Plus (Feasibility)
The purpose of this research is to develop a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase physical activity, healthy…
- Trial name
- NCT03811743
- Testing
- Brenner FIT, By Design, Coordination
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Bariatric Surgery, Sleeve Gastrectomy
Prediction Model for Inadequate Weight Loss After Sleeve Gastrectomy
This study aims to develop and validate a prediction model for estimating the probability of inadequate weight loss one year after sleeve gastrectomy.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Weight Loss
- Trial name
- NCT06157606
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China-Japan Friendship Hospital
Endometrial Atypical Hyperplasia, Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia
Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical Hyperplasia and Grade 1 Endometrial Cancer
The goal of this clinical trial is to learn if a combination treatment of a hormonal intrauterine device (LNG-IUD), semaglutide, and a structured weight loss program can treat endometrial atypical hyperplasia or grade 1…
- Conditions
- Endometrial Atypical Hyperplasia, Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Cancer Stage I, Endometrial Cancer
- Trial name
- SWIFT (NCT07820358)
- Testing
- Semaglutide (Wegovy) weekly injection, LNG-IUD (Progestin), Structured Weight Loss Program
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- The Methodist Hospital Research Institute
Change of Transit or Circulation, Obesity
The Effect of Prebiotics on Gastrointestinal Functioning and Metabolism
The study will investigate the effect of cereal based prebiotic fibres on intestinal health and functioning and host metabolism.
- Trial name
- NCT02491125
- Testing
- soluble wheat bran fibre
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
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