Clinical trials: Weight Changes, Body
Overweight and Obesity, Metabolic Syndrome
Changes in the Hypotalamic-pituitary Region of Patients With Metabolic Syndrome and Obesity
This study aims to identify new morphological and quantitative magnetic imaging parameters of pituitary gland and sellar region in overweight and obese patient at baseline and after 3 years, dividing patients in 3 groups (weight…
- Trial name
- CHIASM (NCT03458533)
- Testing
- Bariatric surgery, Diet and lifestyle changes
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- University of Roma La Sapienza
Obesity & Overweight, Metabolism Changes
Acute and Chronic Effects of Obesity
The goal of this study is to understand if there are differences in the fat, muscle and metabolism of individuals who developed obesity during childhood versus those who developed obesity in adulthood.
- Conditions
- Obesity & Overweight, Metabolism Changes, Lipid Metabolism
- Trial name
- ACEO (NCT07515547)
- Testing
- Weight loss
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Concordia University, Montreal
Severe Acute Malnutrition, Wasting
A Novel Low-Cost Tool for a More Efficient and Reliable Weight-for-Height/Length Assessment
Weight-for-height/length z-score is one of the indicators used to diagnose acute malnutrition. In the existing method, the assessment involves three steps and takes significant time with a wider room for errors.
- Trial name
- Yared's-tool (NCT03780348)
- Testing
- New Method, Existing Method
- Volunteers
- 510 people
- Sponsor
- JSI Research & Training Institute, Inc.
Toxicology, Bariatric Surgery Analgesia
Preoperative Toxicological Screening on Perioperative Anesthetic Management
Background: Preoperative substance use is a growing concern in patients undergoing metabolic bariatric surgery (MBS), but its impact on short-term outcomes remains debated.
- Conditions
- Toxicology, Bariatric Surgery Analgesia, Bariatric Surgery, Substance Use
- Trial name
- NCT07100314
- Testing
- Multi-Drug One Step Screen Test Panel (Urine)
- Where
- Egypt
- Volunteers
- 1,260 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Schizophrenia
Compare the Effects of Bifeprunox and Quetiapine on Weight Changes in Stable Schizophrenic Patients
The primary objective of the study is to evaluate changes in weight short and long term with bifeprunox and quetiapine. Study participation for the subject is 57 weeks.
- Trial name
- NCT00396214
- Testing
- Bifeprunox, Quetiapine
- Where
- 151 sites in United States, Argentina and 12 more
- Volunteers
- 83 people
- Sponsor
- Solvay Pharmaceuticals
Weight Maintenance, Weight Loss
ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
This is an interventional research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
- Conditions
- Weight Maintenance, Weight Loss, Stress, Psychological, Job Stress
- Trial name
- SCULPT-Job (NCT04709549)
- Testing
- Diabetes Prevention Program + Job and Legal Services, Diabetes Prevention Program
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Francisco
Obesity, Overweight
Impact of Satiating Compounds and Hypocaloric Diet on Weight, Cardiometabolic and Osteoarticular Health in Obesity
The main objective of this intervention study is to evaluate the effect of satiating protein and/or fiber bar consumption on weight loss and other osteoarticular and cardiometabolic parameters related to excess weight in subjects…
- Trial name
- COGLUBOCO (NCT07165548)
- Testing
- Experimental Bar (Formulation 1) + Hypocaloric diet (10% energy restriction), Experimental Bar (Formulation 2) + Hypocaloric diet (10% energy restriction), Experimental Bar (Formulation 3) + Hypocaloric diet (10% energy restriction)
- Where
- Spain
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Gestational Diabetes, Weight Loss
Smartphone App to Restore Optimal Weight in Women With Recent Gestational Diabetes
Gestational diabetes (GDM) complicates about 20% of pregnancies in Singapore. These women are at high risk of developing type 2 diabetes years after pregnancy; seven times more likely than normal.
- Conditions
- Gestational Diabetes, Weight Loss, Diet Habit
- Trial name
- SPAROW (NCT03324737)
- Testing
- Interactive Smartphone App
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Obesity, Adolescent
Young Adults With Early-onset Obesity Treated With Semaglutide
Introduction: The increasing prevalence of obesity is particularly pronounced among adolescents. Currently available treatment options consist of structured lifestyle interventions.
- Trial name
- RESETTLE (NCT05574439)
- Testing
- TCOC treatment, Semaglutide 3 mg/ml
- Where
- 2 sites in Denmark
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Signe Torekov
Obesity
Association Between the Change of the Genes With Hormones and Food Consumption of Obese
Obesity is considered one of the most troubling chronic diseases for public health because of its rapid growth in the population.
- Trial name
- NCT02598037
- Testing
- Test meal
- Where
- Brazil
- Volunteers
- 71 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Childhood Obesity
Husky Reads Effectiveness in Increasing Produce Preference and Food Group Identification in Preschool Children
Since 1998, UCONN undergraduate students have volunteered as part of a service- learning course to deliver a program called Husky Reads.
- Trial name
- NCT03338257
- Testing
- Husky Reads Intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- UConn Health
Morbid Obesity
Endoscopic Gastric Tubulization
Endoscopic gastric tubulization is currently proposed in the Digestive Surgery Department of the Nouvel Hôpital Civil, Strasbourg, France, to adult patients with morbid obesity.
- Trial name
- Endosleeve (NCT03554902)
- Testing
- Endoscopic gastric tubulization
- Where
- France
- Volunteers
- 300 people
- Sponsor
- IHU Strasbourg
Bariatric Surgery, Obesity
Endocrinological and Neuronal Aspects of Bariatric Surgery
The overall aim of the proposed project is to investigate the contribution of changes in neuronal food processing, hypothalamic reactivity and hormonal factors to weight loss after bariatric surgery.
- Trial name
- BACEN (NCT04634929)
- Testing
- bariatric surgery, conservative diet
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Heidelberg Medical Center
Prostate Cancer
Improving Energy Balance in Men With Prostate Cancer
RATIONALE: Obesity and overweight are associated with the risk of aggressive disease, and energy balance may play a major role in prostate cancer progression.
- Trial name
- NCT01886677
- Testing
- Immediate diet and exercise intervention, Delayed diet and exercise intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Overweight and Obesity, Nutrition Poor
Im(Proving) the CSA Model
In 1986, The Pioneer Valley in Western Massachusetts was home to one of the first two community supported agriculture (CSA) businesses in the USA.
- Conditions
- Overweight and Obesity, Nutrition Poor, Diet Modification
- Trial name
- NCT03231592
- Testing
- CSA Group, Enhanced Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Community Health Center of Franklin County
Kidney Transplant; Complications, Glomerular Disease
Effect of Moderate Caloric Restriction on Glomerular Growth After Kidney Transplantation
One possible reason that weight gain after transplant may interfere with new kidney function is due to the enlargement of a kidney structure called the glomerulus.
- Conditions
- Kidney Transplant; Complications, Glomerular Disease, Weight Gain, Kidney Transplant
- Trial name
- NCT03607500
- Testing
- caloric intake reduction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Dolutegravir
CHARACTERISE - A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care
The ADVANCE clinical trial compared three recommended first-line regimens two containing dolutegravir head-to-head and demonstrated virological non-inferiority at 48- and 96-weeks respectively1,2, paving the way for the mass…
- Trial name
- CHARACTERISE (NCT05502692)
- Testing
- CHARACTERISE
- Where
- South Africa
- Volunteers
- 200 people
- Sponsor
- University of Witwatersrand, South Africa
Wasting, Moderate Acute Malnutrition
Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition
The purpose of this study is to determine whether an improved corn-soya blend (CSB+) and a new formulated ready-to-use supplementary food (RUSF) are effective in the treatment of moderate acute malnutrition in children.
- Trial name
- NCT01898871
- Testing
- A daily ration of 40 kcal/kg of body weight during 56 days
- Where
- 2 sites in Cameroon
- Volunteers
- 81 people
- Sponsor
- Centre for Food and Nutrition Research, Yaounde
Body Weight Changes, Body Weight
Differences in Fat Mass Estimation Formulas in Physically Active Adult Population and Relation With Skinfold Sums.
The objective of the present study was to analyze the differences between the formulas used to estimate fat mass and to establish the existing relationship with the skinfold sum in anthropometry.
- Trial name
- NCT04429581
- Testing
- Anthropometry
- Volunteers
- 2,458 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Weight Loss, Hypertrophy
Weight Loss Prior Mamma Reduction - A Pilot Study
Due to a higher risk of complications, obese and overweight patients with macromastia are in Denmark prohibited mammoplasty , as BMI must be within normal range, i.e. BMI < 25 kg/m2.
- Trial name
- MAMMARED (NCT02659371)
- Testing
- Low energy diet
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital at Herlev
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