Clinical trials: Weight Changes, Body
Breast Cancer
The Breast Cancer Personalized Nutrition Study
The Breast Cancer Personalized Nutrition (BREACPNT) study will evaluate the effect of a microbiome based personalized diet intervention on control of weight gain, glycemic response, disease outcome and various biomarkers in…
- Trial name
- BREACPNT (NCT04079270)
- Testing
- Nutrition intervention
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Obesity, Glomerulopathy
Dietary Intervention in Obesity-related Glomerulopathy
Obesity-related glomerulopathy (ORG) is a silent comorbidity associated with obesity whose incidence is increasing in parallel to the obesity epidemic.
- Trial name
- ORG-VLCD-2022 (NCT05294770)
- Testing
- Optisource® Plus: Very Low Calorie Diet treatment, Hypocaloric Mediterranean Diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Eating Disorders
Effectiveness of Binge Eating Disorder Treatments
This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).
- Trial name
- NCT00060762
- Testing
- Interpersonal Therapy, Behavioral Weight Loss Treatment, Guided Self Help
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- Stanford University
Weight Change, Body, Obesity
Digital Health Weight Management Among Public Housing Residents
This research will test the efficacy of a weight management intervention through a three-group randomized trial: mHealth only, mHealth+Community Health Worker (CHW) support, versus control group, among residents of Boston's…
- Trial name
- NCT04852042
- Testing
- mHealth, CHW support
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Tufts Medical Center
Cardiovascular Diseases, Obesity
Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics
This project will conduct a pilot hybrid study that examines the implementation (Aims 1 \& 2) and preliminary effectiveness (Aim 3) of PREVENT, a digital health intervention, among patients with overweight/obesity (N=100) using a…
- Trial name
- Rural PREVENT (NCT06397729)
- Testing
- Wait-List Control, PREVENT Tool
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Preterm Infant
Preterm Infant Multicentre Growth Study
The purpose of this study is to improve health professionals understanding of preterm infant growth patterns, and to determine if early growth patterns predict risks of adverse metabolic and cognitive outcomes.
- Trial name
- PreMGS (NCT03064022)
- Testing
- Growth
- Where
- 2 sites in Canada
- Volunteers
- 1,275 people
- Sponsor
- University of Calgary
Weight Loss
Personalized Lifestyle Intervention and Weight Control
This trial aims to investigate whether tailored lifestyle consultation through SNP testing leads to more effective weight loss among overweight or obese individuals compared to general lifestyle guidance for weight control.
- Trial name
- NCT04079972
- Testing
- Obesity-related genetic information disclosure with tailored lifestyle recommendations, Non-obesity-related genetic information disclosure
- Where
- South Korea
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- NaNa Keum
Obesity & Overweight, Type 2 Diabetes Mellitus (T2DM)
MRI Assessment of Pancreatic Fat Changes and Islet Function Recovery After Bariatric Surgery in Obese Patients
This study evaluates changes in pancreatic fat and recovery of pancreatic function in obese patients undergoing laparoscopic sleeve gastrectomy (LSG), a weight-loss surgery.
- Conditions
- Obesity & Overweight, Type 2 Diabetes Mellitus (T2DM), Pancreatic Steatosis, Insulin Resistance
- Trial name
- PANFAT-BS (NCT07464223)
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- yu li，MD
Obesity
Safety and Tolerance of a Nutritional Intervention Program- In.Form 1.2
The study evaluated and the safety, tolerance and acceptability of a lifestyle modification program with nutritional supplementation in generally healthy overweight subjects with cardiometabolic risk factors.
- Trial name
- NCT03098056
- Testing
- PROG2
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nature's Sunshine Products, Inc.
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Binge Eating, Weight Loss
Reducing Binge Eating to Prevent Weight Gain in Black Women
The purpose of the proposed study is to pilot a 6-month, cognitive-behavioral binge eating intervention, Appetite Awareness Training (AAT) to reduce binge eating and prevent weight gain for Black women with a BMI > 25 kg/m^2 and…
- Conditions
- Binge Eating, Weight Loss, Weight Gain Prevention
- Trial name
- NCT03531112
- Testing
- Appetite Awareness Treatment + Lifestyle Modification
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
A Novel Intervention for Weight Loss in Young Adults
Obesity and cardiometabolic risks are significant public health issues, with about two-thirds of U.S. adults overweight or obese.
- Trial name
- NCT06230744
- Testing
- Lifestyle, Lifestyle II
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cachexia
The Investigation of the Mechanism of Cachexia Occurrence for Patients With Gastrointestinal Cancer
The study is going to recruit patients with gastrointestinal cancer, collect clinical data and peripheral blood sample and possible fat samples.
- Trial name
- NCT04594863
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer, Insomnia
The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
The investigators propose a randomized controlled clinical trial in 250 women with a history of early stage breast cancer who are overweight or obese with insomnia to test whether a brief, cognitive-behavioral intervention for…
- Conditions
- Breast Cancer, Insomnia, Weight Gain
- Trial name
- COIN (NCT05780814)
- Testing
- Cognitive-Behavioral Therapy for Insomnia (CBT-I), Sleep Education Control (EDU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Obesity, Bariatric Surgery
Effects of Bariatric Surgery on Insulin
This study, conducted at the NIH Clinical Research Unit (CRU) at the Phoenix Indian Medical Center, will compare the effects of two methods of bariatric surgery, the adjustable BAND and Roux-en-Y gastric bypass, on insulin.
- Conditions
- Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss
- Trial name
- NCT00535600
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Weight Reduction, Health Knowledge, Attitudes, Practice
Behavioral Economics-Based Online Lifestyle Balance Program
The objective of this project is to design a Behavioral Economics Based Online Lifestyle Balance Program that employs behavioral economics to engage and motivate adherence to an Internet-based program.
- Trial name
- NCT03534336
- Testing
- Incentive for Education, Incentive for Weight Loss
- Where
- Singapore
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Weight Loss, Obesity
The Effect of HealthWear on Short-Term Weight Loss
The purpose of this study is to examine the effect of a computer tracking system and energy expenditure device on weight loss in adults.
- Trial name
- NCT00177593
- Testing
- behavioral weight loss
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Morbid Obesity, Weight Loss
Laparoscopic Gastric Bypass Versus Laparoscopic Banded Gastric Bypass Randomized Prospective Clinical Trial
This study try to identify differences in length of operation, weight loss and complications, between two different bariatric surgical techniques, the laparoscopic Roux-en-Y gastric bypass and the laparoscopic Roux-en-Y banded…
- Conditions
- Morbid Obesity, Weight Loss, Postoperative Complications
- Trial name
- LGB-vs-LbGB (NCT02939664)
- Testing
- Banded (with polypropylene mesh) gastric bypass, Gastric bypass
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Puerta de Hierro University Hospital
Obesity, Maternal, Weight Gain, Maternal
The Difference of Weight Gain Tendencies and Obesity During Pregnancy
Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia…
- Conditions
- Obesity, Maternal, Weight Gain, Maternal, Birth Weight, Birth Outcome, Adverse
- Trial name
- NCT06540014
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Overweight
Effect of South Beach Diet (SBD™) Using SBD™ Products Compared to a Calorie-Restricted Diet in Women
The purpose of this study is to examine the effectiveness of the South Beach Diet™ and South Beach Diet™ products compared to a traditional calorie restricted diet.
- Trial name
- NCT00932516
- Testing
- South Beach Diet™ with South Beach Diet™ Products, South Beach Diet™, Calorie restricted diet with South Beach Diet™ Products
- Where
- 4 sites in United States
- Volunteers
- 248 people
- Sponsor
- Mondelēz International, Inc.
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