Clinical trials: Weight Changes, Body
Obesity, Hypertension
Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health
This study will examine the effects of a low carbohydrate diet versus a high carbohydrate diet on weight loss.
- Trial name
- NCT00200720
- Testing
- Atkins diet (low carbohydrate diet), DASH diet (high carbohydrate diet)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Kaiser Permanente
NAFLD
A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men
Using a small Randomized Controlled Trial (RCT) study design, PNPLA3 risk allele carriers (CG/GG genotype) with NAFLD, will be assigned 2:1 to a tailored NAFLD-specific weight loss intervention compared to a wait-list control…
- Trial name
- NCT04186260
- Testing
- NAFLD-specific weight loss intervention, Wait-list control
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Esophageal Spasm, Diffuse
Botulinum Toxin Injection to Treat Diffuse Esophageal Spasm
This study evaluates the effect of botulinum toxin 100 U or saline, injected endoscopically in the distal esophagus, on symptoms and manometry pattern in patients with diffuse esophageal spasm.
- Trial name
- Botox (NCT01432782)
- Testing
- Botulinum Toxin Type A
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Eating Disorder, Binge-Eating Disorder
Improving Weight Loss Outcomes for Binge Eating Disorder.
This study aims to develop and evaluate the efficacy of a behavioral weight loss treatment approach for individuals with binge eating disorder to both reduce their binge eating behaviors and lose weight.
- Conditions
- Eating Disorder, Binge-Eating Disorder, Weight Loss, Binge Eating
- Trial name
- NCT03712462
- Testing
- Acceptance-Based Behavioral Weight Loss Therapy for BED, Standard Behavior Therapy
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Drexel University
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Diabetes, Physical Activity
Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans
The goal of this clinical trial is to learn if an enhanced, culturally, socially, and structurally tailored Diabetes Prevention Program (E-DPP) can improve weight loss and related diabetes risk factors in African American adults…
- Conditions
- Diabetes, Physical Activity, Food Security, Nutrition Security
- Trial name
- NCT07560969
- Testing
- Culturally-tailored, enhanced adaption of Diabetes Prevention Program
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Missouri, Kansas City
Weight Loss, Bone Density
Metabolic Health, Bones and Nuts During Weight Loss in Adults
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group.
- Conditions
- Weight Loss, Bone Density, Obesity and Overweight
- Trial name
- BERN (NCT06949280)
- Testing
- Peanut Snack Experimental, Nut-free Snack
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obesity, Gestational Weight Gain
Maternal, Adiposity, Metabolism, and Stress Study
The MAMAS study is built on the premise that simple recommendations for diet and exercise may not be enough to encourage healthy weight gain during pregnancy.
- Trial name
- MAMAS (NCT01307683)
- Testing
- Mindful Moms
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Weight Loss
A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes
A pilot randomized trial was done to test the feasibility integrating virtual reality (VR) into standard behavioral weight loss treatment.
- Trial name
- NCT04534088
- Testing
- Standard Behavioral Weight Loss plus Non-Weight-Related VR app, Standard Behavioral Weight Loss plus Weight-Related VR app
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Overweight or Obesity
Effect of a Modified 5:2 Intermittent Fasting Diet on Population With Overweight or Obesity in China
This study aimed to investigate the effects of the modified 5:2 IF dietary intervention on the Chinese population with overweight or obesity based on a self-controlled clinical trial.
- Trial name
- NCT06552403
- Testing
- A modified 5:2 intermittent fasting diet
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Tongde Hospital
Obesity and Cardiovascular Risk, Insulin Resistance
Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
Obesity is a chronic disease of global public health concern, contributing to cardiovascular disease, type 2 diabetes and certain cancers.
- Conditions
- Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
- Trial name
- MOWRI (NCT07297290)
- Testing
- Metformin
- Where
- 2 sites in Nigeria
- Volunteers
- 220 people
- Sponsor
- University Of Nigeria Teaching Hospital
Obesity, Abdominal, Dyslipidemias
Dietary Approaches for Cardiometabolic Health
This pilot study aims to recruit 30 adults with abdominal obesity, without major chronic disease, and test whether clinical dietary advice that is solely focused on the timing of eating (time restricted eating), has an effect on…
- Conditions
- Obesity, Abdominal, Dyslipidemias, Insulin Resistance, Blood Pressure
- Trial name
- DACH (NCT03527290)
- Testing
- Time Restricted Eating, Standard Cardiometabolic Health Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Growth Alteration, Obesity
Secular Change of Height in Turkish Young Adults
Current Turkish growth reference charts based on anthropometric measurements of individuals with high socioeconomic status in Istanbul in 1989-2002 (TK2002) had shown an increase of mean adult height (1.4 and 2.7 cm in males and…
- Trial name
- NCT06514924
- Testing
- height and weight measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 465 people
- Sponsor
- Istanbul University
Obesity, Diabetes Mellitus, Type 2
Stage-based Exercise Promotion Study
The purpose of this study is to increase regular physical activity among students by fostering self-management competencies. The intervention was implemented as paper-pencil intervention.
- Trial name
- STEPS (NCT01289145)
- Testing
- Motivational intervention, Volitional intervention, Active Control
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Obesity, Overweight
The Peer Assisted Lifestyle Intervention
The PAL intervention uses a new software tool delivered on tablets to facilitate 5As-based weight management counseling with a peer health coach and the VA PACT healthcare team to promote goal-setting, behavior change, and weight…
- Trial name
- PAL (NCT03163264)
- Testing
- Peer Assisted Lifestyle, Enhanced Usual Care
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- VA Office of Research and Development
Obesity, Morbid, Type2 Diabetes
The Endocrine Secretome After Gastric Bypass Surgery
Examination of the molecular phenotype and composition of endocrine cells in the gastrointestinal tract correlated to analyses of blood for hormones/analytes before and after Roux-en-Y gastric bypass surgery in morbidly obese…
- Trial name
- NCT03093298
- Testing
- Enteroscopy with biopsy sampling and mixed meal test
- Volunteers
- 28 people
- Sponsor
- Filip Krag Knop
Obesity
Resveratrol Stimulates Insulin Sensitivity in Subjects With Obesity and Insulin Resistance
There is evidence that resveratrol can improve insulin resistance in rodents and humans with obesity and it can also improve muscle mitochondrial content mediated through activation of AMPK.
- Trial name
- NCT06961279
- Testing
- Resveratrol
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Myopia, Obesity
Trial of a Novel Family-Based Intervention to Increase Outdoor Time and Fitness
This study aims to implement a new family-based health behavior community program to increase time spent outdoors and physical activity among Singapore children aged 6 to 12 years in a 1-year randomized clinical trial.
- Trial name
- FIT (NCT01388205)
- Testing
- Family-based Outdoor program
- Where
- Singapore
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Obesity
Zonisamide for Weight Reduction in Obese Adults
The primary aim of this study is to assess long-term weight loss efficacy of zonisamide relative to placebo in obese patients prescribed a dietary intervention.
- Trial name
- NCT00275834
- Testing
- Zonisamide
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Duke University
Obesity, Obese
Cost-effectiveness Study of a Multidisciplinary Weight Loss Method to Improve the Health Condition of Obese Patients
Prospective, observational, multicenter study based on a registry of patients with obesity and associated comorbidities undergoing a standardized multidisciplinary weight loss method with a 2-year follow-up.
- Trial name
- PRONOCOST (NCT05833464)
- Where
- Argentina
- Sponsor
- Protein Supplies SL
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