Clinical trials: Weight Changes, Body
Obesity (Disorder), Metabolic Disorders
Hormonal and Microbiota Modulation After Endoscopic Sleeve Gastroplasty
Obesity is a chronic disease with a rapidly increasing prevalence, expected to affect up to 25% of the French population by 2030, and is associated with significant morbidity, mortality, and healthcare burden.
- Trial name
- HOVIGAMI-ESG (NCT07576777)
- Testing
- Laparoscopic sleeve gastrectomy, Endoscopic sleeve gastroplasty
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Diseases, Obesity
Intermittent Low Energy Diet in CKD: MIX UP Feasibility Study
This study proposes to investigate the acceptability and efficacy of intermittent VLED (5:2 diet) plus exercise, compared with the investigator's established Weight Management Programme (WMP), in obese patients with CKD, using…
- Trial name
- MIX-UP (NCT03736551)
- Testing
- 5:2 diet, Renal Weight Management Programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- King's College Hospital NHS Trust
Healthy
Diets With a Spectrum of Fat Intake for Preventing Obesity: A Randomized Controlled-feeding Trial
The aim of the current study is to evaluate the effects of diets with three levels of dietary fat on weight change and related cardiometabolic risk factors in a 6-month randomized controlled-feeding trial.
- Trial name
- NCT02355795
- Testing
- low-fat diet, moderate-fat diet, high-fat diet
- Where
- China
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Breast Cancer, Obesity
Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women
RATIONALE: A low-calorie diet and/or exercise program may help lower an overweight or obese postmenopausal woman's risk of developing breast cancer.
- Conditions
- Breast Cancer, Obesity, Weight Changes
- Trial name
- NCT00470119
- Testing
- behavioral dietary intervention, Exercise intervention
- Where
- United States
- Volunteers
- 439 people
- Sponsor
- Fred Hutchinson Cancer Center
Weight Loss
Plicated Laparoscopic Adjustable Gastric Banding Study
Compare plicated laparoscopic adjustable gastric banding to standard laparoscopic adjustable gastric banding in prospective clinical trial.
- Trial name
- NCT01944111
- Testing
- Plication
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tenet Healthcare Corporation
Obesity
Body Heat Content and Dissipation in Obese and Normal Weight Adults
This study will investigate how different parts of the body lose body heat and will measure the heat released by specific areas such as the limbs and abdomen.
- Trial name
- NCT00266500
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hormones
CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
Background: Functional hypothalamic amenorrhea (functional HA) is a condition where a woman s period stops for a temporary time. This is due to improper function of the hypothalamus.
- Trial name
- NCT02858336
- Testing
- NEA, DEA
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Body Weight Changes, Body Weight
Differences in Fat Mass Estimation Formulas in Physically Active Adult Population and Relation With Skinfold Sums.
The objective of the present study was to analyze the differences between the formulas used to estimate fat mass and to establish the existing relationship with the skinfold sum in anthropometry.
- Trial name
- NCT04429581
- Testing
- Anthropometry
- Volunteers
- 2,458 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Infant, Newborn, Weight Loss
Effect of Kangaroo Care on Phyiological Weight Loss in Term Newborns
The aim of the study is to evaluate the effect of kangaroo care on physiological weight loss in term newborns.
- Trial name
- NCT05001334
- Testing
- Kangaroo care training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Muscle Mass and Strength, Obesity & Overweight
Function and Lean Mass Preservation With Resistance Exercise During a GLP-1RA Treatment
This study aims to investigate the effect that a structured, progressive resistance exercise program may have on maintaining the muscle mass and physical function of overweight/ obese females whilst they experience a tirzepatide…
- Conditions
- Muscle Mass and Strength, Obesity & Overweight, Physical Function
- Trial name
- FLEX (NCT07457437)
- Testing
- Progressive Resistance Exercise Training Program, Habitual physical activity guidelines
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Obesity
Effects of Weight Loss on Vascular Function in Obese Subjects
To evaluate the effect of weight loss on vascular function in obese with poor cardiovascular health. The investigators will evaluate the effects of weight loss on total and central body adiposity, blood pressure, central…
- Trial name
- NCT04198519
- Testing
- Weight Loss
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mario Fritsch Neves
Stunting, Severe Acute Malnutrition
Changes in Nerve Electro Physiologic Properties in Children Before and After Correction of Malnutrition
The goal of this clinical trail study is to measure neurophysiologic parameters to assess the effect of malnutrition on the peripheral nervous system and their response to treatment in three categories (SAM, severe wasting, and…
- Conditions
- Stunting, Severe Acute Malnutrition, Wasting
- Trial name
- NCT05891457
- Testing
- Nutritional Intervention
- Where
- Bangladesh
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status…
- Trial name
- NCT01719900
- Testing
- Pulse fibre, Control
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity
Whey Protein, Resistance Training, and Changes in Body Composition
The objective of this project is to determine the effect of 9 months of progressive resistance training with daily whey protein supplements on the body composition (changes in muscle and fat) in young adults.
- Trial name
- NCT01186536
- Testing
- Whey Protein supplement, Soy Protein Supplement, Carbohydrate supplement
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Dietary Habits, Health Knowledge, Attitudes, Practices
Evaluation Nutrition Education Intervention on Pulse and Cereal Mix for Complementary Food in Southern Ethiopia
The overall purpose of the study is to evaluate nutrition education interventions to promote pulse incorporated complementary food to the wider rural community through the government system to improve maternal knowledge, attitude…
- Conditions
- Dietary Habits, Health Knowledge, Attitudes, Practices, Wasting
- Trial name
- NCT02638571
- Testing
- enhanced education on pulse use in complementary foods
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Obesity, Weight Loss
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
In the proposed study, we will be evaluating the effects of pylorus sparing antral myotomy alone, without concomitant endoscopic sleeve gastroplasty (ESG), on weight loss for subjects undergoing the procedure with a history of…
- Conditions
- Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild
- Trial name
- BEAM (NCT05713071)
- Testing
- Bariatric Endoscopic Antral Myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Pregnancy-Related Condition, Unspecified, Overweight or Obesity
Supporting Lifestyle Change in Obese Pregnant Mothers Through Wearable Internet-of-Things (SLIM)
Maternal obesity increases risks for the mother and her child. It is crucial to arouse the pregnant and postpartum women´s willingness of change and motivation to take care of their own and their unborn child´s health.
- Trial name
- SLIM (NCT04826861)
- Testing
- SLIM intervention
- Where
- Finland
- Volunteers
- 55 people
- Sponsor
- University of Turku
Major Depressive Disorder
Do Antidepressants Induce Metabolic Syndromes METADAP Study
Since antidepressants and antipsychotics have common receptorial mechanisms of action (H1 antagonism, 5HT2 antagonism), the impact of antidepressants in terms of metabolic syndromes is a matter of concern.
- Trial name
- METADAP (NCT00526383)
- Testing
- Tricyclic antidepressants
- Where
- France
- Volunteers
- 624 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypogonadism, Obesity
Testosterone, Metformin, or Both, for Hypogonadism in Obese Males
The purpose of this study is to examine the effects of metformin, testosterone, or both, in males with obesity-related hypogonadism.
- Trial name
- NCT02514629
- Testing
- Metformin, Testosterone Undecanoate, Metformin + Testosterone Undecanoate
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
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