Clinical trials: Weight Changes
Cachexia
Regimen for the Treatment of Cachexia in Subjects With NSCLC
Cachexia is a presentation of a chronic manifestation of acute metabolic stress, a hypercatabolic nutritional state in which the normal fat and protein sparing mechanisms are not functioning and increased nutrition is not…
- Trial name
- VT-122 (NCT00527319)
- Testing
- VT-122 low dose, VT-122 high dose
- Where
- 8 sites in United States, India
- Volunteers
- 37 people
- Sponsor
- Vicus Therapeutics
Cachexia
Study to Evaluate the Safety and Efficacy of 13 Weeks of the Selective Androgen Receptor Modulator (SARM) GSK2881078 in Chronic Obstructive Pulmonary Disease (COPD)
Impaired physical function and muscle dysfunction are a major consequence of COPD, which may be associated with increased mortality, poor quality of life and increased health care use.
- Trial name
- NCT03359473
- Testing
- GSK2881078
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline
Weight, Food Choice
Promoting Employee Health Through The Worksite Food Environment
This project tests a scalable and sustainable approach to weight gain prevention in a population of employees by using the worksite environment to deliver personalized feedback about worksite food purchases, daily calorie goals…
- Conditions
- Weight, Food Choice, Nutrition Intake
- Trial name
- ChooseWell 365 (NCT02660086)
- Testing
- Personalized nutrition feedback
- Where
- United States
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity
Remote Delivery of Weight Management for Adults With IDD
The purpose of this study is to compare different weight loss programs in people with IDD to see which program works better.
- Trial name
- NCT03291509
- Testing
- Video Conference Meetings, In-person Meetings, Enhanced Stop Light Diet
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Obesity, Overweight
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program.
- Trial name
- SURMOUNT-3 (NCT04657016)
- Testing
- Tirzepatide
- Where
- 65 sites in United States, Argentina and 2 more
- Volunteers
- 579 people
- Sponsor
- Eli Lilly and Company
Postpartum Weight Retention
Laser Acupuncture for Postpartum Weight Retention
Objective: To determine the therapeutic effect of acupuncture on postpartum weight retention. Methods: 66 subjects after delivery with postpartum weight retention will be randomly divided into laser acupuncture and control group.
- Trial name
- NCT02840916
- Testing
- laser acupuncture
- Where
- Taiwan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Leukemia, Lymphoma
Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With Cancer
RATIONALE: Cyproheptadine hydrochloride may help improve appetite and lessen weight loss caused by cancer or cancer treatment. It is not yet known whether cyproheptadine hydrochloride is more effective with or without nutritional…
- Conditions
- Leukemia, Lymphoma, Malnutrition, Myelodysplastic Syndromes
- Trial name
- NCT00949117
- Testing
- Ensure, PediaSure, cyproheptadine hydrochloride
- Volunteers
- 9 people
- Sponsor
- University of South Florida
Weight Loss
Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention
The present study is a non-inferiority trial comparing the efficacy of a lifestyle intervention delivered entirely via an online social network to a traditional lifestyle intervention delivered via group meetings.
- Trial name
- NCT02646618
- Testing
- Get Social, Traditional, Smartphone
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Kangaroo Mother Care, Preterm Infant
Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
We will conduct an individually randomised, controlled, superiority trial with two parallel groups; an intervention arm allocated to receive KMC and a control arm receiving 'standard' care.
- Conditions
- Kangaroo Mother Care, Preterm Infant, Death; Neonatal, Hypothermia, Newborn
- Trial name
- OMWaNA (NCT02811432)
- Testing
- Kangaroo mother care, Standard care
- Where
- 4 sites in Uganda
- Volunteers
- 2,221 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Weight Loss
University Of Pennsylvania Weight Loss Study
This is a 4-arm, randomized controlled trial to evaluate the effectiveness of financial incentives to motivate and sustain long-term weight loss.
- Trial name
- NCT01167634
- Testing
- Deposit contract with a 1:1 match, Deposit contract with a 2:1 match, Deposit Contract with no match
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Pennsylvania
Obesity
A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity
The purpose of the study is to evaluate the efficacy, tolerability and safety of LIK066 to support dose selection for Phase 3 development in Japanese adults with obesity disease.
- Trial name
- NCT03320941
- Testing
- LIK066
- Where
- 24 sites in Japan
- Volunteers
- 126 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Weight Loss
Total Lifestyle Coaching Pilot Study (TLC)
The investigators aim to develop, pilot and evaluate a new "Total Lifestyle Coaching" (TLC) program, that will address both information and behavior-change aspects of nutrition education for patients whose body mass index (BMI)…
- Conditions
- Obesity, Weight Loss, Telemedicine
- Trial name
- TLC (NCT03025217)
- Testing
- Total Lifestyle Coaching (TLC)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anemia, Cancer Fatigue
Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
This phase II trial studies the side effects of ex vivo-activated autologous lymph node lymphocytes infusion and to see how well they work in treating patients with chronic lymphocytic leukemia.
- Conditions
- Anemia, Cancer Fatigue, Chronic Lymphocytic Leukemia, Fever
- Trial name
- NCT02530515
- Testing
- Ex Vivo-activated Autologous Lymph Node Lymphocytes, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Overweight
Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
The goal of this pilot trial is to learn about the optimal intensity level of goals in a digital weight loss intervention among adults with overweight or obesity.
- Conditions
- Obesity, Overweight, Weight Loss, Health Behavior
- Trial name
- NCT05715242
- Testing
- Core Behavioral Weight Loss Intervention, Easier Step Goal, Harder Step Goal
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Stanford University
Dementia, Alzheimer Type, Weight Loss
Partners at Meals - Respite Care and Home (PAM)
The goal of this study was to test the efficacy of a mealtime intervention in respite care centers for people with dementia and their caregivers.
- Trial name
- PAM (NCT03622814)
- Testing
- Partners at Meals, Enhanced Usual Condition
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obesity, Food Insecurity
FoodRx for Obesity Treatment
This study is a 3-group, parallel design, randomized controlled trial (RCT) in 105 adults with obesity and food insecurity that will compare BWL-Alone (including standard-of-care referral and connection with community food…
- Trial name
- NCT05635019
- Testing
- BWL+VOUCHER, BWL+HOME, Behavioral weight loss counseling (BWL)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Weight Loss, Postpartum Weight Retention
Postpartum Weight Loss for Women at Elevated Cardiovascular Risk
The aim of this study is to test the feasibility and effectiveness of a 16-week online behavioral weight loss program compared to usual care to promote weight loss in the postpartum period among women with cardiovascular risk…
- Conditions
- Weight Loss, Postpartum Weight Retention, Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
- Trial name
- EMPOWER-Mom (NCT04914819)
- Testing
- Online Behavioral Weight Loss Program, Virtual weigh-in
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Pennsylvania
Smoking Cessation, Obesity
A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers
The purpose of this study is to determine the efficacy, acceptability, and feasibility of an intervention that provides a behavioral weight gain prevention intervention in advance of smoking cessation treatment in individuals…
- Trial name
- NCT05136430
- Testing
- Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Brown University
Pulmonary Disease, Chronic Obstructive (COPD)
Inspiratory Flow Rates Achieved by the COPD Patients Through Breezhaler®, Ellipta® and Handihaler® Inhaler Devices
The purpose of this study was to compare dynamic inspiratory flow rates achieved by a population of Chronic Obstructive Pulmonary Disease (COPD) patients through the Breezhaler®, Ellipta® and Handihaler® dry powder inhaler (DPI)…
- Trial name
- NCT02596009
- Testing
- Breezhaler®, Ellipta®, Handihaler®
- Where
- 5 sites in Argentina
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Weight Loss
Phone Coaching for Weight Loss Maintenance
The purpose of this study was to examine whether 4 consecutive weeks of phone coaching aids in recovery from weight regain during weight loss maintenance.
- Trial name
- NCT04293055
- Testing
- Maintenance program, Phone coaching
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital