Clinical trials: Weight Gain
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Weight Loss, Hormone Disturbance
Effects of Weight Loss on Nutritional Mediated Hormone Secretion
Investigative trial with aim of 1. the description of the hormonal and metabolic response to meals containing different compositions of macronutrients 2.
- Conditions
- Weight Loss, Hormone Disturbance, Weight Gain
- Trial name
- RepDiet (NCT02649907)
- Testing
- nutritional stimulation via different testmeals, Nutritional counseling, formula diet
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pregnancy, Overweight
Preventing Obesity in Military Communities: Mother-Baby
Women with pre-pregnancy obesity, women who exceed recommended weight gain during pregnancy, and children who experience rapid and excess growth during the first year of life are all at risk for subsequent obesity.
- Conditions
- Pregnancy, Overweight, Obesity
- Trial name
- NCT03249324
- Testing
- Positive-Gain Counseling (PGC), Usual Care
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Obesity, Overweight
Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care
Up to 50% of obese patients are not interested in, or ready for, weight loss. Clinical practice guidelines clearly recommend that these patients avoid gaining weight.
- Conditions
- Obesity, Overweight, Overnutrition, Nutrition Disorders
- Trial name
- D0479 (NCT03003403)
- Testing
- Intervention Program
- Where
- United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Duke University
Thinness, Health Behavior
How do Super Lean Subjects Keep Resistant to Body Weight Gain?
Obesity is the 5th leading cause of global death, and is major risk factors for many chronic diseases, such as type 2 diabetes, cardiovascular diseases, hypertension and cancer.
- Conditions
- Thinness, Health Behavior, Genetics
- Trial name
- NCT03221322
- Testing
- Superlean
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Leukemia, Acute Leukemia
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and, along with lymphoblastic lymphoma, represents the most common group of childhood lymphoid malignancies.
- Conditions
- Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma
- Trial name
- STEP-ALL (NCT07634653)
- Testing
- Exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Obesity, Weight Gain
Effectiveness Trial of a Dissonance-Based Obesity Prevention Program
Obesity is a major US public health problem. Few obesity prevention programs have reduced risk for weight gain over follow-up and those that have are very intensive, making dissemination difficult and costly.
- Conditions
- Obesity, Weight Gain, Eating Disorders
- Trial name
- Project Health (NCT01680224)
- Testing
- Healthy Weight, Project Health
- Where
- 4 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Obesity, Gestational Weight Gain
Maternal, Adiposity, Metabolism, and Stress Study
The MAMAS study is built on the premise that simple recommendations for diet and exercise may not be enough to encourage healthy weight gain during pregnancy.
- Trial name
- MAMAS (NCT01307683)
- Testing
- Mindful Moms
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Food Preferences, Obesity
Vending Labeling Sales and Intercepts Study
The aim of this study is to compare the impact of 4 different types of front of package (FOP) food and beverage messages: 1) green labels on healthy foods, 2) red/yellow/green labels on less healthy/moderately healthy/healthy…
- Conditions
- Food Preferences, Obesity, Weight Gain
- Trial name
- NCT06260176
- Testing
- exposure to healthy labels only, exposure to healthiness information, exposure to physical activity equivalents
- Where
- United States
- Volunteers
- 1,065 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Diet
Project Diabetes: Weight Gain Prevention in Hispanic Girls (GEMAS Study)
Over the past 30 years obesity has reached epidemic proportions in the United States (Ogden et al, 2006). While this epidemic affects all socioeconomic levels, certain racial/ethnic groups such as Hispanics, are…
- Conditions
- Obesity, Diet, Exercise, Behavioral Research
- Trial name
- GEMAS (NCT00797615)
- Testing
- Active intervention, Alternative Intervention
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Childhood Obesity
Josef Ressel Centre Perinatal Programming
Background: Metabolic imprinting through early childhood nutrition seems to play an important role in the aetiology of obesity. Overweight at age two and later in life is associated with excessive weight gain as early as three…
- Trial name
- JRP (NCT03634930)
- Testing
- observation
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Moenie van der Kleyn
Overweight Adolescents, Overweight
Pilot Program for Targeted Prevention of Child or Adolescent Weight Gain
This study will examine whether family-based interpersonal psychotherapy (FB-IPT) is an effective tool for helping pre-adolescent girls and boys at risk for become obese to reduce weight gain.
- Trial name
- NCT00263536
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hyperinsulinemia, Insulin Resistance
EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance
The goal of the study is to identify and treat women with midlife weight gain who have normal blood sugars, but increased insulin levels (hyperinsulinemia) following the performance of a glucose tolerance test.
- Conditions
- Hyperinsulinemia, Insulin Resistance, Obesity
- Trial name
- EMPOWIR (NCT00618072)
- Testing
- metformin and rosiglitazone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Lifestyle, Weight Gain
Healthy Living in Pregnancy
Multicenter and multidisciplinary public health project in 10 regions of Bavaria, a federal state of Germany, targeting maternal and fetal health.
- Conditions
- Lifestyle, Weight Gain, Pregnancy
- Trial name
- GeliS (NCT01958307)
- Testing
- Lifestyle intervention
- Where
- 5 sites in Germany
- Volunteers
- 2,286 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
First-episode Psychosis
HIIT in Patients With a First-episode Psychosis
This study aims to estimate the effect of a 3-month High Intensity Interval Training on antipsychotic-induced weight gain in patients with a first episode of psychosis, as well as to determine whether these effects are maintained…
- Trial name
- NCT04792476
- Testing
- High Intensity Interval Training
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Intervención Temprana en Psicosis de Cantabria (ITPCan)
Weight Gain
Growth and Safety Clinical Trial on a New Infant Formula
The aim of this study is to assess age-appropriate growth of healthy infants fed a new infant formula. In this randomized, controlled trial, healthy, term, formula-fed infants will be randomized to one of two infant formulas: a…
- Trial name
- NCT05508750
- Testing
- New Infant Formula, Commercial Infant Formula
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Jovie USA, LLC
Obesity
Preventing Obesity in the Worksite: A Multi-Message, Multi-"Step" Approach
The purpose of this research study is to develop, implement, and evaluate a multi-component obesity prevention program in a workplace setting.
- Trial name
- Go! (NCT01585480)
- Testing
- Weight Gain Prevention Intervention
- Where
- United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Weight-Gain Prevention
A Two-Week Study of the Efficacy and Safety of Mifepristone in the Prevention of Olanzapine-Induced Weight Gain
This is a two-week study testing the efficacy and safety of mifepristone in the prevention of olanzapine-induced weight gain in healthy male volunteers by measuring changes in body weight and BMI.
- Trial name
- NCT00455442
- Testing
- Mifepristone
- Where
- India
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics