Clinical trials: Weight Loss, completed
Obesity, Weight Loss
Oxidative Stress and L-CBMN Cytome Assay in Obese After 3 Weeks VLCD
Obesity leads to physiological imbalance resulting in hyperglycemia, dyslipidaemia and inflammation and can generate systematic oxidative stress through multiple biochemical mechanisms.
- Conditions
- Obesity, Weight Loss, DNA Damage
- Trial name
- NCT05055154
- Testing
- Very low calorie diet
- Where
- Croatia
- Volunteers
- 26 people
- Sponsor
- Special Hospital for Extended Treatment of Duga Resa
Bariatric Surgery
Gaining Optimism After Weight Loss Surgery (GOALS) I
This study examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have recently undergone…
- Trial name
- GOALS (NCT04867902)
- Testing
- Positive Psychology-Motivational Interviewing Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Obesity
Comparison of a Technology-based System and an In-person Behavioral Weight Loss Intervention in the Severely Obese
The purpose of this study is to examine the effect of an enhanced technology-based system, that involves a wearable device to measure calories burned combined with a website, in comparison to previous versions of similar…
- Trial name
- NCT01537796
- Testing
- In-Person weight loss, FIT weight loss, FIT-BT weight loss
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Colorectal Cancer, Diet Habit
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
A Mediterranean Diet (MedDiet), a largely plant-based dietary pattern, is relevant to CRC prevention and microbial production of anti-cancer metabolites in observational studies.
- Trial name
- Bridge CRC (NCT04753359)
- Testing
- Med, WL
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cachexia, Squamous Cell Carcinoma
Role of Myostatin, Activin A and Follistatin Cachexia of ENT Cancers
The main objective of our study was to determine the modifications of blood myostatin and activin A concentrations associated with head and neck cancers.
- Conditions
- Cachexia, Squamous Cell Carcinoma, Head and Neck Cancer
- Trial name
- MYOCACH (NCT03162042)
- Testing
- Tumor removal
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Intellectual Disability, Weight Loss
POWERSforID: A Telehealth Weight Management System for Adults With Intellectual Disability
POWERSforID is a 24 week randomized control trial designed to assess the feasibility of a telehealth and coaching intervention for improving health outcomes of adults with intellectual disability.
- Conditions
- Intellectual Disability, Weight Loss, Motivational Interviewing, Telehealth
- Trial name
- POWERSforID (NCT03139760)
- Testing
- POWERSforID
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer, Weight Loss
Lifestyle, Exercise and Nutrition Study 1
The specific aims of this study are to determine the efficacy and cost-effectiveness of a weight loss program compared with usual care (control) treatment on 6-month changes in body weight, body fat, and serum hormones in breast…
- Trial name
- LEAN (NCT02109068)
- Testing
- Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Childhood Obesity
"Mandometer®" Study for Managing Childhood Obesity
We run a successful clinic in Bristol for children with severe obesity who already demonstrate many features to suggest they are at increased risk of early diabetes and heart disease.
- Trial name
- NCT00407420
- Testing
- Mandometer, Lifestyle
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Bristol
Type 2 Diabetes Mellitus, Overweight
Lifestyle Modification for Obesity-Related Type 2 Diabetes
Dietary carbohydrate is the major determinant of postprandial glucose levels, and preliminary evidence suggests that low carbohydrate diets improve glycemic control when accompanied by weight loss.
- Conditions
- Type 2 Diabetes Mellitus, Overweight, Obesity
- Trial name
- NCT00415688
- Testing
- Low carbohydrate, ketogenic diet, Low glycemic index, reduced calorie diet
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Robert C. Atkins Foundation
Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
This study will assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in patients with COPD and cachexia. The primary outcome will be a change in thigh muscle volume compared to placebo.
- Trial name
- NCT01669174
- Testing
- BYM338
- Where
- 9 sites in United States, Netherlands and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Weight Loss, Inflammation
Effect of Very-low Calorie Diet and Synbiotic Supplementation in Gut Microbiota (Pronokal Method)
The present study aimed to investigate the changes produced in gut microbiota by a very-low-calorie-ketogenic diet followed by a low calorie diet, whether the use of synbiotics is able to modulate gut microbiota diversity and…
- Trial name
- Pronokal (NCT03530501)
- Testing
- Diet, Synbiotic1, Synbiotic2
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Overweight, Obesity
Disseminating Effective Habits for Long-Term Weight Loss
The purpose of the study is to determine whether using a web-based weight loss website can help overweight individuals lose weight.
- Trial name
- NCT00709501
- Testing
- Disseminating Effective Habits for Long-term Weight Loss, Achieve Together website
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Penn State University
COPD, Cachexia
Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia
SF-K002 is a pilot study in patients with moderate to severe COPD suffering from involuntary weight loss. The study is 12 weeks, double-blinded, placebo controlled and the main objective is to study the safety and tolerability of…
- Trial name
- NCT02442908
- Testing
- Nutrifriend Cachexia
- Where
- 4 sites in Sweden
- Volunteers
- 45 people
- Sponsor
- Smartfish AS
Obesity (BMI>30), Obesity (BMI > 35)
FABP4 Response After Roux-en-Y Gastric Bypass
This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months.
- Conditions
- Obesity (BMI>30), Obesity (BMI > 35), Insulin Resistance, Bariatric Surgery
- Trial name
- FABP4-RYGB (NCT07774208)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
Obesity, Overweight
Effects of Almond Versus Pistachio on Weight Loss
The purpose of the current study is comparing the effect of almond and pistachio, as the two common types of nuts, consumption on healthy obese and overweight female who following a hypocaloric diet for 12 weeks.
- Trial name
- NCT03120455
- Testing
- Almond Group, Pistachio Group, Nut free group
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Psoriatic Arthritis, Obesity
Small Changes Behavioural Weight Loss Treatment Approach for Psoriatic Arthritis Patients With Comorbid Obesity
Psoriatic Arthritis (PsA) is a type of auto-immune condition that affects roughly 90,000 Canadians. Patients with PsA often experience joint pain, skin problems, and issues with mobility that negatively impact their quality of…
- Trial name
- NCT05225623
- Testing
- BWLT, Waitlist Control for BWLT
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Calgary
Obesity
Chronic Intermittent Cold Exposure on Weight Loss
1. To test whether chronic intermittent cold exposure is more effective in programmed body weight loss when compared to conventional programmed weight loss. 2. To measure the metabolic responses (e.g.
- Trial name
- CICE (NCT01312090)
- Testing
- Whole body cryotherapy, counseling and behavioral therapy for weight loss
- Volunteers
- 20 people
- Sponsor
- Helsinki University Central Hospital
Weight Reduction
A Lifestyle Program on Healthy Weight in Postpartum Period
The aim of this study is to examine the impact of lifestyle intervention on postpartum weight loss. So the investigators will have two groups in this study.
- Trial name
- NCT02620059
- Testing
- Lifestyle Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Obesity, Prostate Cancer
Effect of Weight Loss on Prostate Cancer Pathology
The purpose of this study is to determine if weight loss prior to radical prostatectomy effects chemical substances in the blood stream and prostate tissue that may affect prostate cancer development and progression.
- Trial name
- NCT00475982
- Testing
- Weight Loss, No Weight Loss Group
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Obesity, Weight Loss
Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment
Project ReLearn is testing the efficacy and cost-effectiveness of an Artificial Intelligence system for optimizing weight loss coaching.
- Trial name
- ReLearn (NCT05231824)
- Testing
- Standard Behavioral Weight Loss Treatment, AI-optimized Behavioral Weight Loss Treatment
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Oregon Research Institute
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