Clinical trials: Weight Loss, completed
Weight Loss
The Addition of Self-compassion Skills Training to a Behavioral Weight Loss Program Delivered Using Video Conferencing Software
The current study examined the efficacy, feasibility, and acceptability of: 1) adding self-compassion (SC) skills training to a standard behavioral weight loss program (BWLP), and 2) utilizing video conferencing software to…
- Trial name
- NCT04756973
- Testing
- Behavioral weight loss program
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity
BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus
The purpose of this study is to assess the weight loss effect of lorcaserin during and at the end of 1 year of treatment in overweight and obese patients with Type II diabetes mellitus treated with metformin, sulfonylurea (SFU)…
- Trial name
- NCT00603291
- Testing
- Lorcaserin 10 mg once daily (QD), Lorcaserin 10 mg twice a day (BID)
- Where
- United States
- Volunteers
- 604 people
- Sponsor
- Eisai Inc.
Obese, Cigarette-smoking
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.
- Conditions
- Obese, Cigarette-smoking, Schizophrenia
- Trial name
- NCT02736474
- Testing
- Naltrexone, Bupropion
- Volunteers
- 22 people
- Sponsor
- Shanghai Mental Health Center
Body Weight Decreased
Proof of Concept Study; The Effect of an Encapsulated Nutrient Mixture on Ileal Brake Activation
Intraileal infusion of nutrients results in a reduction in food intake. A previous study by our group showed that both sucrose and casein infusion resulted in an increase in satiety and release of gastrointestinal peptides and a…
- Trial name
- NCT02635659
- Testing
- Encapsulated nutrients
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Glucose Intolerance
Vitamin D to Improve Glucose Metabolism and Reduce Inflammation in Obese Adolescents
The investigators' project will study the effects of optimizing the vit D status of obese adolescents on markers of glucose metabolism and inflammation.
- Conditions
- Obesity, Glucose Intolerance, Inflammation
- Trial name
- NCT00994396
- Testing
- Vitamin D 3 cholecalciferol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Missouri-Columbia
Type 2 Diabetes
The eHealth Diabetes Remission Trial - Pilot Study
Ten study participants will consume a low-calorie total diet replacement for 12 weeks, have a 6-week food reintroduction phase (week 13-18) and continue with the weight loss maintenance phase until the end of the study (week…
- Trial name
- eDIT-pilot (NCT04805996)
- Testing
- Diabetes remission using total diet replacement and eHealth contact with the healthcare provider
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Julia Otten
Obesity, Surgery
Gastric Bypass, Gastric Band or Sleeve Gastrectomy to Treat Obesity
Obesity is an increasing health problem in the United Kingdom (UK) and is predicted to worsen. In the UK and worldwide the three most commonly performed operations are laparoscopic adjustable gastric banding ('BAND surgery')…
- Conditions
- Obesity, Surgery, Quality of Life, Weight Loss
- Trial name
- ByBandSleeve (NCT02841527)
- Testing
- Gastric Band, Gastric Bypass, Sleeve Gastrectomy
- Where
- 12 sites in United Kingdom
- Volunteers
- 1,351 people
- Sponsor
- University of Bristol
Obesity, Weight Loss
Monday-Focused Tailored Rapid Interactive Mobile Messaging for Weight Management 2
This study, involves the implementation and evaluation of a Monday-focused, individually tailored mobile health application to assist overweight or obese adults who would like to achieve a healthful weight.
- Conditions
- Obesity, Weight Loss, mHealth, Healthy Diet
- Trial name
- M-TRIMM2 (NCT04506996)
- Testing
- Monday-Focused Tailored Rapid Interactive Mobile Messaging for Weight Management, Monday-Focused Written Messages for Weight Management, Educational Materials
- Volunteers
- 154 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Overweight, Obesity
3mg Liraglutide for Overweight or Obesity
In this study investigators will investigate the beneficial metabolic sequelae of Liraglutide in patients with obesity or overweight; including changes in vital signs, anthropometric characteristics (weight, body mass index and…
- Conditions
- Overweight, Obesity, Infertility, Female
- Trial name
- NCT03885297
- Testing
- Saxenda, Lifestyle modification, Metabolomics
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Body Weight, Weight Loss
Computer-Based Weight Maintenance in Primary Care
This randomized trial tested the hypothesis that there would be an incremental benefit of personalized coaching and PCP support in an EHR-based intervention designed to help primary care patients maintain recent intentional…
- Conditions
- Body Weight, Weight Loss, Motor Activity
- Trial name
- MAINTAIN-PC (NCT01946191)
- Testing
- 24 months of personalized coaching through the EHR patient portal, with 24 scheduled contacts., Online self-monitoring, Real-time updates to Primary Care physicians
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of Pittsburgh
Obesity, Body Fat
Effects of Lipoic Acid and Eicosapentaenoic Acid (EPA) in Human Obesity
The aim of the study is to analyze the effects of Lipoic acid and/or EPA supplementation on weight loss, lipid profile, insulin resistance, oxidative and inflammation parameters, metabolomic profile as well as on adipose tissue…
- Conditions
- Obesity, Body Fat, Insulin Resistance
- Trial name
- OBEPALIP (NCT01138774)
- Testing
- Double blind dietary intervention with EPA and lipoic acid
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Overweight and Obesity
Analysis of Metabolic State in Normal-weight and Overweight-obese After Lifestyle Improvement and/or Weight Loss
The aim of this study is to design and validate a test, METAHEALTH-TEST, based in gene expression analysis in blood cells, to quickly and easily analyse metabolic health.
- Trial name
- METAHEALTH (NCT04402697)
- Testing
- Dietary and physical activity intervention
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Orthognathic Surgery
Dietary Interventions to Reduce Postoperative Weight Loss and Improve Recovery After Orthognathic Surgery
Objectives This randomized controlled trial aimed to assess whether structured dietary interventions, implemented both before and after orthognathic surgery, could minimize postoperative weight loss and thereby enhance recovery…
- Trial name
- NCT07431268
- Testing
- Intervention group receiving nutritional supplements through G-tube and Protein drinks, Intervention group receiving nutritional supplements through Protein drinks
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aalborg University Hospital
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Weight Loss
A Prospective Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina TM) as an Aid for Endoscopic Gastric Reduction.
Surgery is the only effective treatment for morbid obesity and can be divided into restrictive surgeries (Lap Band and Sleeve gastrectomy), malabsorptive surgeries (Biliary pancreatic deviation and duodenal switch) or a…
- Trial name
- Endomina (NCT02582229)
- Testing
- Endomina
- Where
- 3 sites in Belgium, Czechia and 1 more
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Obesity, Overweight
FitLink: Improving Weight Loss Maintenance by Using Digital Data to Provide Support and Accountability
Most adults in the U.S. are overweight or obese and find maintenance of weight loss difficult. This study is designed to aid in the development of a lifestyle modification program that can facilitate weight loss maintenance…
- Conditions
- Obesity, Overweight, Overweight and Obesity, Weight Loss
- Trial name
- NCT03337139
- Testing
- Gold Standard Behavior Therapy for Weight Loss, Standard Remote Behavior Therapy for Weight Loss, Digital Data Sharing Behavior Therapy for Weight Loss
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Drexel University
Obesity
Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss
The primary aim of this study is to is to determine if intermittent fasting (IMF) is an effective dietary strategy for treatment of obesity.
- Trial name
- NCT03411356
- Testing
- Daily Caloric Restriction (DCR), Intermittent Fasting (IMF)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Bariatric Surgery Candidate
Does Antrum Size Matter in Sleeve Gastrectomy?
Laparoscopic sleeve gastrectomy (LSG) is currently the most frequent primary bariatric procedure performed worldwide. LSG is safe and effective in terms of excess weight loss.
- Trial name
- NCT04323072
- Testing
- Wide antrectomy, Smal antrectomy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Overweight and Obesity
Attentive Eating for Weight Loss
This trial examined whether a smartphone application designed to encourage a more attentive eating style could help people to lose weight, compared to a control group.
- Trial name
- NCT03602001
- Testing
- Attentive eating smartphone application., Standard dietary advice and text tips.
- Where
- United Kingdom
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
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