Clinical trials: Weight Loss, completed
Cachexia, Non-Small Cell Lung Cancer
Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2)
The administration of Anamorelin in patients with Stage III-IV non-small cell lung cancer-cachexia (NSCLC-C) is expected to increase appetite, lean body mass, weight gain, and muscle strength.
- Trial name
- NCT01387282
- Testing
- Anamorelin HCl
- Where
- 46 sites in United States, Australia and 5 more
- Volunteers
- 495 people
- Sponsor
- Helsinn Therapeutics (U.S.), Inc
Obesity
Diet and Body Composition
The investigators hypothesize that differential dynamics in fat depots in response to two opposing dietary strategies mediate the beneficial metabolic effects during weight loss and regain phases.
- Trial name
- CENTRAL (NCT01530724)
- Testing
- Weight-loss diet strategy (+) exercise (PA), weight loss (-) exercise (PA)
- Where
- Israel
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Weight Loss
Body Contouring Surgery After Massive Weight Loss
Body contouring (BC) surgery after major weight loss (MWL) requires extensive and multiple procedures. Yet, there are inconsistent data regarding the outcome after BC procedures.
- Trial name
- NCT02174458
- Testing
- Body Contouring Surgery
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Basel, Switzerland
Overweight and Obesity
A Trial Comparing Two Approaches to Weight Loss
This study compared the recently developed Transforming Your Life (TYL) weight loss program to the Diabetes Prevention Program (DPP), considered the "Gold Standard" in behavioral weight loss treatment.
- Trial name
- NCT02671110
- Testing
- Transforming Your Life, Diabetes Prevention Program
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Robert Carels
Body Weight Changes
Concurrent Training and Nutritional Management in Cancer
A case control study with before-after design. A concurrent training and a nutritional management intervention was offered by a patient with head and neck cancer, in order to compare outcomes related to strength and endurance…
- Trial name
- NCT03720015
- Testing
- Physical exercise, Nutritional management
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Universidad Francisco de Vitoria
Obesity
State-wide Health Approach to Increase Reach and Effectiveness: Study 2
Behavioral weight loss programs can successfully reduce body weight, but these programs are available to limited numbers of overweight and obese individuals.
- Trial name
- SHARE (NCT01560130)
- Testing
- Shape Up Rhode Island + Online weight loss program, Shape Up Rhode Island + Online weight loss program + Groups, Shape Up Rhode Island + Online weight loss + Incentives
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Pediatric Obesity
NOURISH: Nourishing Our Understanding of Role Modeling to Improve Support and Health
The percentage of overweight children between the ages of 6 and 11 has nearly tripled in the last three decades, and rates are even higher among African Americans.Overweight children are at-risk for numerous health problems, thus…
- Trial name
- NOURISH (NCT00628030)
- Testing
- NOURISH, Wellness Group
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Overweight, Postmenopausal
Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors
Obesity is an epidemic and the majority of breast cancer survivors are overweight or obese. The American Cancer Society has called for weight loss treatment to be standard of care for overweight women with breast cancer.
- Conditions
- Overweight, Postmenopausal, Breast Cancer
- Trial name
- VCC0910 (NCT01482702)
- Testing
- weight loss intervention, Weight Loss
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Vermont
Overweight and Obesity, Ketogenic Diet
A Weight Loss RCT Comparing Keyto vs Weight Watchers
Very low-carbohydrate ketogenic diet may have beneficial metabolic and weight loss effects, however, adhering to this diet may be challenging.
- Trial name
- NCT04165707
- Testing
- Keyto device + app, Weight Watchers app
- Where
- Canada
- Volunteers
- 155 people
- Sponsor
- University of British Columbia
Obesity, Diabetes
Semaglutide 2.4 mg in Patients With Poor Weight-loss
A double-blinded, randomised, placebo-controlled trial of semaglutide 3.0 mg/ml in patients with poor weight-loss following bariatric surgery.
- Conditions
- Obesity, Diabetes, Metabolic Syndrome
- Trial name
- BARI-STEP (NCT05073835)
- Testing
- Semaglutide 3 mg
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University College, London
Breast Cancer
Moving Forward: A Weight Loss Intervention for African-American Breast Cancer Survivors
This is a randomized intervention study to examine the effects of the Moving Forward Guided Weigh Loss Intervention compared to a self-guided weight loss program on BMI and behavioral, biological, and psychosocial outcomes in…
- Trial name
- NCT02482506
- Testing
- MF-WLP, SG-WLP
- Volunteers
- 240 people
- Sponsor
- Medical College of Wisconsin
Obesity, Overweight
Chewing Gum for Weight Loss
This is a randomized controlled trial of the effects of chewing gum on body weight. The investigators will randomly assign 200 overweight or mildly obese adults to one of two groups.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT00971347
- Testing
- Extra sugar-free chewing gum sticks, nutrition brochure
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Weight Loss, Weight Change
Body Composition & REE Responses to Bariatric Surgery
The aim of this study is to measure important components of weight change in patients who underwent bariatric surgery on measures of fat mass and its distribution and fat-free mass (FFM) (bone mineral density, skeletal muscle…
- Trial name
- NCT00682058
- Testing
- Follow-up post-bariatric surgery
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Columbia University
Cachexia
A Study to Assess the Safety, Tolerability and Pharmacokinetics of TCMCB07 in Single and Multiple Ascending Doses in Health Subjects
This study will test an experimental drug named TCMCB07 for the treatment of cancer cachexia. Cachexia is a syndrome characterized by weight loss, anorexia, weakness or lack of energy, and anemia.
- Trial name
- NCT05529849
- Testing
- TCMCB07
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Endevica Bio
Obesity
Substituting Mushrooms for Meat to Control Body Weight
This is a one-year clinical trial to assess weight-loss, weight-maintenance, and biochemical parameters following a weight-control diet using either standard food guide pyramid alone, or standard food guide pyramid with…
- Trial name
- NCT01177085
- Testing
- Weight-loss and weight-maintenance diets
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Obesity, Hypertension
The Effect of Phentermine and B12 on Weight Loss Among Obese Patients
This is a pilot study designed to test the hypothesis that the combination of phentermine and B12 will result in significantly greater weight loss among obese patients compared to phentermine alone.
- Trial name
- NCT01719185
- Testing
- Phentermine and B12, Phentermine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Dr. Michael Lang
Lower Extremity Amputation
Weight Loss Intervention for Individuals With Lower Extremity Amputation
The purpose of this study is to pilot test a program to help overweight and obese individuals with a lower extremity amputation (LEA) lose weight and become more physically active.
- Trial name
- MOVE-LEAP (NCT02085785)
- Testing
- Coached group, Self-directed control group, Screened only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Overweight or Obesity
Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study
This is a single arm phase II study designed to determine the effects of pharmacotherapy and a remote behavioral weight loss intervention on weight loss in breast cancer survivors who are overweight or obese, and the impact of…
- Trial name
- A-NEW (NCT04499950)
- Testing
- Contrave, Behavioral Weight Loss
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Overweight and Obesity
The Lean Living Study
This study investigates whether walnuts help to promote weight loss, associated with increased meal satiety and satisfaction, in 100 overweight and obese men and women who are participating in a 6-month behavioral weight loss…
- Trial name
- NCT02501889
- Testing
- Walnut-rich weight loss diet, Standard weight loss diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Weight Loss
Active Nutrition Program on Weight Loss
The study will evaluate the impact of the Active Nutrition 60-day program from USANA on weight loss and related measures, such as body composition, physical appearance/body shape, perceived wellness, and biochemical markers of…
- Trial name
- NCT06249698
- Testing
- meal replacements and supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Memphis
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