Clinical trials: Weight Loss Trial
Obesity, Overweight
Soy Fiber Improves Weight Loss and Lipid Profile
The aim of this study is to examine the effects of soy fiber on body weight, body composition and blood lipids in overweight and obese participants.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT01802840
- Testing
- biscuits supplemented with soy fiber
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Zhejiang University
Cachexia
The Impact of Oligo-Fucoidan in Cancer Cachexia and Sarcopenia
Fucoidan also ameliorates tumour and chemotherapy-induced muscle atrophy and -related cachectic symptoms in vivo and in vitro. To evaluate the effect of fucoidan in cancer cachexia or sarcopenia in cancer patients.
- Trial name
- OFCS (NCT05623852)
- Testing
- fucoidan
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University WanFang Hospital
Obesity, Weight Reduction
Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults
This prospective, open-label, single-arm, single-center interventional pilot trial aims to evaluate the efficacy and safety of low-dose semaglutide for weight loss and cardiometabolic improvement in obese Pakistani adults without…
- Conditions
- Obesity, Weight Reduction, Cardiometabolic Risk Factors
- Trial name
- NCT07513168
- Testing
- Locally available low-dose semaglutide (0.25 mg, 0.5 mg, 1 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Asian Institute Of Medical Sciences
Weight Loss, Obesity and Overweight
BrainWeighve App Feasibility Study
Childhood obesity within the United States has been a growing concern over the past number of years, and if not addressed, leads to detrimental health outcomes for youth as they move into adulthood.
- Trial name
- NCT05530538
- Testing
- BrainWeighve App
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity, Binge-Eating Disorder
MindOb: A 12-month Computerized Mindfulness-based Intervention for Obese Individuals
The purpose of this study is to evaluate the efficacy of a daily 12-month computerized mindfulness-based intervention in obese patients diagnosed with Binge Eating Disorder (BED) on: impulsive eating, motivation toward exercise…
- Trial name
- MindOb (NCT02571387)
- Testing
- Mindfulness-based intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University of Paris 5 - Rene Descartes
Cachexia, CKD
A Multimodal Integrated Intervention for Kidney Cachexia
This lay description has been written in conjunction with, and the content approved by our Patient and Public Involvement collaborators.
- Trial name
- MMIEAD (NCT07107087)
- Testing
- Multi-Modal Integrated Intervention Combining Exercise, Anti-inflammatory & Dietary Advice (MMIEAD)
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen's University, Belfast
Metabolic Syndrome
Strategic Lifestyle Intervention for Metabolic Syndrome (SLIM-MET)
This study is a randomized, parallel-group, observer-masked clinical trial. A total of 200 obese participants with MetS will be enrolled.
- Trial name
- NCT06271200
- Testing
- Strategic lifestyle and drug interventions, Control
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Health Research Institutes, Taiwan
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Overweight, Obesity
Hockey Fans in Training (Hockey FIT): Improving Men's Health Through the Power of Sport
Hockey Fans in Training (Hockey FIT) is a 12-month (3-month active phase and 9-month minimally-supported phase) weight loss and healthy lifestyle program for middle-aged, male hockey fans with overweight or obesity, delivered by…
- Trial name
- NCT03636282
- Testing
- Hockey FIT Program (Immediate Delivery)
- Where
- 40 sites in United States, Canada
- Volunteers
- 997 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Weight Cycling, Obesity & Overweight
Effect of Meal Frequency on Diet Self-Efficacy and Perceived Stress in Women With Weight Cycling
The World Health Organization (WHO) defines obesity as abnormal or excessive fat accumulation in the body that may adversely affect health.
- Conditions
- Weight Cycling, Obesity & Overweight, Dietary Self-efficiacy, Perceived Stress
- Trial name
- NCT07582952
- Testing
- 3-meal diet plan, A dietary intervention comprising 3 main meals and 3 snacks
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Medipol University
Obesity & Overweight
Effects of Inulin on Cardiometabolic Risk Factors in Individuals Using Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA ) Medications for Weight Loss
The goal of this double-blind randomized placebo-controlled supplement study is to investigate if the supplement of inulin (prebiotics, 10 grams per day) has beneficial effects on cardiometabolic risk factors in overweight or…
- Trial name
- NCT07611552
- Testing
- inulin (prebiotics)
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- Huazhong University of Science and Technology
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Overweight and Obesity
Sustaining the Reach of a Scalable Weight Loss Intervention Through Financial Incentives
This study seeks to assess how different incentive strategies may reduce the initial attrition gap when implementing weight management in a primary care clinic predominantly serving African American patients.
- Trial name
- NCT04225234
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Nebraska
Obesity
Protocol for a Feasibility of a Motivational Interviewing for Weight Loss in Adults
Abstract Introduction: This pilot study will determine the recruitment feasibility, retention, and adhesion for a motivational interviewing program for weight loss in adults according to the processes of change in weight loss.
- Trial name
- MWL (NCT05769907)
- Testing
- Intervention Group
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus
The REmission of Diabetes Using a PlAnt-based Weight Loss InteRvention (REPAIR) Trial
The goal of this clinical trial is to learn if a plant-based intensive lifestyle intervention can achieve remission of diabetes.
- Trial name
- REPAIR (NCT06906172)
- Testing
- Plant-based intensive lifestyle intervention, Standard of Care
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Toronto
Obesity, Status Post Sleeve Gastrectomy
Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Background: Metabolic Bariatric Surgery, including a surgery called vertical sleeve gastrectomy, is the most effective weight loss treatment for severe obesity.
- Trial name
- NCT04883346
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cachexia; Cancer, Anorexia
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.
Cancer-associated anorexia-cachexia is an insidious syndrome that has a major impact on the patient's quality of life, but is also associated with a significant reduction in survival.
- Trial name
- NCT03283488
- Testing
- Mirtazapine, Megestrol
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo
Obesity, Weight Loss
An Open-Label Pilot Trial of Alpha Lipoic Acid (ALA) for Weight Loss in Schizophrenia
The aim of this study is to collect pilot data to compare the effectiveness of treatment with Alpha Lipoic Acid (ALA) for reduction in body weight in 40 obese outpatients with schizophrenia or schizoaffective disorder in an…
- Conditions
- Obesity, Weight Loss, Schizophrenia
- Trial name
- ALA (NCT01355952)
- Testing
- Alpha Lipoic Acid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yale University
HIV Infections, HIV Wasting Syndrome
A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss
To test the hypothesis that the predominant accrual of fat rather than lean body mass (LBM) that occurs during treatment of HIV-associated wasting with megestrol acetate may be improved by treatment with megestrol acetate and…
- Trial name
- NCT00001079
- Testing
- Testosterone enanthate, Megestrol acetate
- Where
- 21 sites in United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Colitis, Ulcerative, Obesity
Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
Approximately 20-40% of patients with ulcerative colitis (UC) are obese. The investigators have demonstrated that obesity adversely impacts disease course in patients with UC, leading to higher risk of persistently active…
- Trial name
- NCT04721873
- Testing
- Phentermine-Topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego