Clinical trials: Weight Loss Trial
Osteoarthritis, Obesity
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Loss
This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).
- Trial name
- IM-LOSEIT-I (NCT02928471)
- Testing
- Intensive dietary intervention
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Henrik Gudbergsen
Overweight, Obesity
Increasing the Effectiveness of the Diabetes Prevention Program
The Diabetes Prevention Program (DPP) is highly effective in promoting weight loss in overweight and obese individuals (e.g., 7% average loss of body weight), and thereby reducing the risk of developing weight-related health…
- Trial name
- NCT02008435
- Testing
- Enriched GLB, Standard GLB
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- McGill University
Obesity
Weight Loss and Reversing T2D Through eHealth Coaching
Background: Systematic reviews conclude that Internet and mobile interventions can significantly change lifestyle in a short time span.
- Trial name
- LIVA (NCT03788915)
- Testing
- Online dietetic lifestyle counseling, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 340 people
- Sponsor
- University of Southern Denmark
Obesity, Obesity Recidivism
Financial Incentives and Weight Loss in Failed Bariatric Surgery
This national, prospective, multicenter, and randomized study seeks to evaluate the effect of financial incentives on weight loss in individuals who experience weight regain following bariatric surgery.
- Trial name
- BARIACADO (NCT06910735)
- Testing
- Control, Threshold financial incentive, Proportional financial incentive
- Where
- 12 sites in France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bariatric Surgery
Gaining Optimism After Weight Loss Surgery (GOALS) I
This study examines the feasibility, acceptability, and preliminary impact of an adapted positive psychology-motivational interviewing (PP-MI) intervention for physical activity among patients who have recently undergone…
- Trial name
- GOALS (NCT04867902)
- Testing
- Positive Psychology-Motivational Interviewing Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Weight Loss, Weight Gain
Time Restricted Eating for WeIght LoSs MainTenance-2
The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a…
- Conditions
- Weight Loss, Weight Gain, Weight Loss Maintenance
- Trial name
- TWIST-2 (NCT07190170)
- Testing
- TRE, Weight-Loss Maintenance Advice
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- NYU Langone Health
Obesity, Muscle Loss
The POWER BARIATRIC Trial: Physical Outcomes With Exercise Regimens on BARIATRIC Patients
This study aims to determine how different types of exercise regimens (resistance, aerobic, or combined exercise regimens) can be used to minimize muscle loss and mobilize body fat in severely obese patients after bariatric…
- Conditions
- Obesity, Muscle Loss, Adiposity
- Trial name
- POWER (NCT04777305)
- Testing
- Physical activity training
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Overweight, Obese
PREPARE: A Randomized Trial of a Pre-pregnancy Weight Loss Intervention
The US obesity epidemic is being transmitted to the next generation. Growing evidence suggests that both a mothers' weight at pregnancy onset, and excessive weight gain during pregnancy, are associated with increased risk of…
- Trial name
- NCT02346162
- Testing
- Weight management, Usual Care Control
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cardiometabolic Conditions, Hypertension (HTN)
To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years
In this study, the investigators are conducting a Type 3 hybrid effectiveness-implementation trial to evaluate the implementation of the Community Health Workers (CHW)-delivered PILI Pasifika Program (PPP) across 3 regions, the…
- Conditions
- Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes
- Trial name
- NCT07387393
- Testing
- PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Hawaii
Obesity
Acceptance Based Behavioral Intervention for Weight Loss: A Randomized Trial
The proposed project is testing two behavioral interventions designed to improve long-term weight loss among participants who struggle with eating in response to stress or emotional experiences.
- Trial name
- NCT01461421
- Testing
- Nutrition Education, Behavioral Weight Loss Strategies, Standard Cognitive Techniques
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Miriam Hospital
Obesity, Overweight
Does Motivational Interviewing Improve Behavioral Weight Loss Outcomes for Obesity?
The purpose of this study is to determine whether adding motivational interviewing (MI) to a behavioural weight loss program (BWLP) results in improved weight loss for adults who are overweight or obese.
- Trial name
- BWLP+MI (NCT02649634)
- Testing
- Motivational Interviewing, Attention Control
- Volunteers
- 135 people
- Sponsor
- University of Calgary
Obesity & Overweight, Cardiometabolic Health Indicators
Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1s
The purpose of this research is to compare weight loss among 3 groups: 1. people who stay on a GLP-1 drug at full strength (Group 1) 2.
- Trial name
- OFF-RAMP (NCT07832084)
- Testing
- GLP-1 dose reduction, non-GLP weight loss medication, Maintenance of GLP-1 dose
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Jing Luo
Visceral Fat, Liver Dysfunction
Weight Loss Effect on Circulating Liver Enzymes
To investigate weight loss effect with mild calorie restriction on circulating levels of liver enzymes in nondiabetic and overweight subjects with high visceral fat area [visceral fat area (VFA) at L4 ≥ 100 cm²].
- Trial name
- NCT02992639
- Testing
- Control group, Weight loss group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Overweight and Obesity, Overweight Adolescents
Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults.
This study assesses whether oral supplementation with vitamin D contributes to the reduction of body mass index and lipid profile in adolescents and young adults.
- Conditions
- Overweight and Obesity, Overweight Adolescents, Vitamin D Deficiency
- Trial name
- SIMBAIII (NCT04377386)
- Testing
- 1000 IU D vitamin, 200 IU D vitamin
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Cardiovascular de Colombia
Weight Loss, Weight Change, Body
Does the Timing of When High Intensity Intermittent Exercise is Undertaken Matter?
The participants will visit the laboratory on 3 occasions, once for a preliminary visit and a further two occasions to complete experimental trials in a randomised order.
- Conditions
- Weight Loss, Weight Change, Body, Nutritional and Metabolic Disease
- Trial name
- HIIE (NCT04122209)
- Testing
- HIIE-First, Continuous-First
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Chronic Pain, Osteoarthritis
A Mobile Intervention to Reduce Pain and Improve Health-III
The experience of chronic pain powerfully and negatively affects quality of life and functional independence in aging. Unfortunately, while as many as three in four older adults experience chronic pain, few have access to…
- Conditions
- Chronic Pain, Osteoarthritis, Obesity and Overweight, Inactivity
- Trial name
- MORPH-III (NCT06623669)
- Testing
- MORPH, Measurement Only
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University
Malnutrition
Nutritional Intervention in a Cross-sector Model for the Rehabilitation of Geriatric Patients
Based on an established Follow-home-programme offered at discharge from hospital the aim of this study is to test a model of how nutritional intervention in elderly patients can be systematized and quality assured in the…
- Trial name
- NCT01776762
- Testing
- Individual nutritional therapy
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Obesity, Overweight
Changing Eating Behavior Using Cognitive Training
Obesity is a global health problem. New and more efficient interventions are needed to overcome this disease. This randomized clinical trial aims to evaluate the effectiveness of changing eating behavior using cognitive training.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT04450524
- Testing
- Hypnosis, Food inhibition training, Control
- Where
- 2 sites in Romania
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Obesity, Food Habits
Study of the Effectiveness of Breakfast Recommendations On Reducing Body Weight
This is an experiment that will compare the effect of recommending breakfast consumption, or breakfast skipping, on body weight.
- Trial name
- NCT01781780
- Testing
- General Nutrition Recommendations, Breakfast Recommendation, No Breakfast Recommendation
- Where
- 5 sites in United States, Denmark
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- David Allison, Phd
Severe to Morbid Obesity and Type 2 Diabetes
Study of Weight Loss Using Gastric Stimulation in Obese Patients With Type 2 Diabetes
The purpose of this study is to test the effect of an implanted device that stimulates the stomach on weight loss in patients suffering from obesity and type 2 diabetes.
- Trial name
- ASSIST (NCT00200018)
- Testing
- Enterra Therapy System (H9900014)
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- MedtronicNeuro