Clinical trials: Weight Management
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Safety/Effacy
Effects of a Nutritional Supplement Combination on Body Weight Management
Title: A Phase IV, Open-label, Single-Center Study on the Effects of a Nutritional Supplement Combination on Body Weight Management over a 90-day period
- Trial name
- NCT01725958
- Testing
- Nutritional supplement and protein shakes
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Intervention Video (I), Weight Control Video (C1)
Web Based Intervention to Reduce Weight Bias Among Dietitians
Weight bias in dietitians is prevalent and may affect patient care. The investigators conducted a randomized controlled trial to test if explicit and implicit bias could be influenced by a short, 20 minute educational video.
- Conditions
- Intervention Video (I), Weight Control Video (C1), Weight Neutral Control Video (C2)
- Trial name
- NCT04177784
- Testing
- Online Educational Videos
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Lymphedema
The Women In Steady Exercise Research (WISER) Survivor Trial
WISER Survivor is a one year weight loss and exercise study for sedentary breast cancer survivors who are overweight or obese with breast cancer related lymphedema.
- Trial name
- WISER Survivor (NCT01515124)
- Testing
- Exercise Intervention, Weight Loss Intervention
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Obesity
IG vs ID Bitter Administration
We want to investigate whether bitter compounds, denatonium benzoate and quinine hydrochloride, have a distinct effect on gastrointestinal hormone release after infusion into the stomach or duodenum.
- Trial name
- IG vs ID (NCT03985865)
- Testing
- Intragastric quinine hydrochloride, Intragastric denatonium benzoate, Intraduodenal quinine hydrochloride
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type 2 Diabetes, PreDiabetes
Promote Health With Digital Tools Among Adults With Type 2 Diabetes/Prediabetes and/or Hypertension
The goal of this hybrid type II effectiveness-implementation trial is to evaluate whether an intersectoral, digitally enabled, family-based intervention can prevent and manage type 2 diabetes mellitus (T2DM) and hypertension…
- Conditions
- Type 2 Diabetes, PreDiabetes, Hypertension, Obesity & Overweight
- Trial name
- DigiCare4You (NCT05648383)
- Testing
- mHealth self-management intervention, Standard care
- Where
- 4 sites in Albania, Bulgaria and 2 more
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity and Obesity-related Medical Conditions
Management of Obese Patients With Gastroesophageal Reflux Disease .
The aim of this study is to evaluate the efficacy Sleeve gastrectomy with cruroplasty with or without ligamentum teres wrapping for management of morbidly obese patients with concomitant reflux symptoms.
- Trial name
- NCT06599489
- Testing
- surgery ..operation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hossam Mahmoud Ibrahim
Overweight, Metabolic Syndrome
Effectiveness of IRK-19® on Body Weight Control
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract (IRK-19®) on weight management.
- Trial name
- NCT05542160
- Testing
- Pumpkin seed extract (IRK-19)
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Greenyn Biotechnology Co., Ltd.
Overweight and Obesity, Weight Loss
microRNA Testing for Identification of Personalized Weight Management
Certain blood markers are related to one's ability to successfully lose weight by diet and exercise. Currently, the laboratory tests used to measure these blood markers are expensive and time-consuming.
- Trial name
- NCT04217850
- Testing
- 250 kcal Dietary Energy Restriction, Aerobic Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Obesity
Effects of a Probiotic on Body Weight
Probiotics administration is associated with health benefits on gut barrier integrity and immunological functions of the gastrointestinal tract.
- Trial name
- NCT01106924
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Theory-Based Obesity Intervention Program for Women
The aim of this study is to examine the effect of education and counseling given to women according to the Theory of Planned Behavior on weight management.
- Trial name
- NCT05027750
- Testing
- Application of The Theory of Planned Behaviour For Weight Control
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Obesity
WE Project: 2.0 Grassroots Wellness Coaching (Phase 2)
African American adults that live in economically disadvantaged areas are at an increased risk for obesity and cardiometabolic disease.
- Trial name
- NCT06172582
- Testing
- 12-week lifestyle intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Healthy, Obesity
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
The primary objective of this trial is to assess bioequivalence of two formulations of survodutide (formulation A and formulation B6) after multiple-dose treatment in male and female trial participants living with overweight or…
- Conditions
- Healthy, Obesity, Overweight
- Trial name
- NCT07407348
- Testing
- Formulation A, Formulation B6
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Intermittent Fasting
Effects of Timed Restricted Eating on Body Composition, Metabolism, and Cardiovascular Health
This study is looking at whether eating all meals within a 6-hour window each day (called Time-Restricted Eating, or TRE) can improve body composition, metabolism, heart health, and blood markers over 12 weeks.
- Trial name
- NCT07574177
- Testing
- Time-Restricted Eating (TRE), Time-Restricted Eating with Intermittent Energy Restriction (TRE+IER)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Obesity
Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects
The main purpose of this study is to examine the effect of prolonged (72 hour) administration of glucagon compared to placebo on energy expenditure in healthy, non-diabetic, obese subjects.
- Trial name
- GIO B (NCT03139305)
- Testing
- Glucagon
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Obesity
Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity
This randomized, double-blind placebo-controlled study was intended to measure the effects of the GWMP with Release supplement versus GWMP with placebo supplement in a representative group of obese subjects with or without…
- Trial name
- NCT03842501
- Testing
- Release Supplement
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Golo
Obesity
Health After Birth Intervention Trial
This trial is to assess the feasibility of a larger, definitive RCT and determine the clinical effectiveness of an NHS 1:1 programme versus a modified programme with a low carbohydrate dietary intervention (as per Feinman and…
- Trial name
- HABIT (NCT05137691)
- Testing
- Adapted NHS weight management 1:1 programme, NHS 1:1 weight management programme
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity, Type 2 Diabetes
Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism
Gut microbiota is being increasingly recognized as an important factor in fat distribution, insulin sensitivity and glucose and lipid metabolism.
- Trial name
- NCT01983046
- Testing
- Three different mixture of acetate, butyrate and propionate and palcebo
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Depression - Major Depressive Disorder, Psychological Well Being
Peer-Supported E-Health Intervention for College Student Weight Management and Mental Health
This study will test whether adding peer support and online education can help college students manage their weight and improve their mood: we plan to enroll 300 full-time university students and randomly assign them to one of…
- Conditions
- Depression - Major Depressive Disorder, Psychological Well Being, Obesity Prevention
- Trial name
- NCT06966661
- Testing
- Peer Support Intervention, Peer Support and eHealth Intervention
- Where
- China
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou