Clinical trials: Weight Reduction
Overweight and Obesity
Weight Loss Intervention With Lean Muscle Mass Retention
Overweight and obesity (i.e., excess body fat) is a worldwide health problem, which predisposes individuals to various metabolic diseases.
- Trial name
- WLMR (NCT05607628)
- Testing
- Low Calorie Animal Protein Meals, Low Calorie Plant Protein Meals
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Obesity, Overweight
Effect of Orlistat in Body Composition
The purpose of this study is to determine if a 24 week weight loss program with orlistat 60 mg will produce greater changes in body composition compared to placebo.
- Trial name
- NCT00752726
- Testing
- Orlistat
- Where
- 3 sites in United States, Sweden
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Weight Loss, Obesity
A Mentor-Based Approach to Long-Term Weight Loss
The purpose of this study to examine the effect of having a weight loss mentor on long-term weight loss in overweight adults.
- Trial name
- NCT00177697
- Testing
- behavioral weight loss program
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Weight Loss, Bariatric Surgery Candidate
Resting Metabolic Rate Testing in Bariatric Surgery Patients
This study evaluates if measuring resting metabolic rate (the number of calories the body burns at rest) before surgery can help predict successful weight loss after surgery.
- Trial name
- NCT03221543
- Testing
- ReeVue Indirect Calorimeter
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Obesity, Overweight
Chewing Gum for Weight Loss
This is a randomized controlled trial of the effects of chewing gum on body weight. The investigators will randomly assign 200 overweight or mildly obese adults to one of two groups.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT00971347
- Testing
- Extra sugar-free chewing gum sticks, nutrition brochure
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Blood Pressure, Sleep Health
The Sleep2BWell Trial
Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities.
- Conditions
- Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity
- Trial name
- NCT06565104
- Testing
- Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
Metabolic Syndrome X, Cachexia
The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases.
- Conditions
- Metabolic Syndrome X, Cachexia, Insulin Resistance
- Trial name
- NCT00172614
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity
The Effects of Dairy Products on Energy Balance
The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately…
- Trial name
- MEPEB (NCT01199835)
- Testing
- High Calcium intake from dairy products
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Adaptation of the Diabetes Prevention Program for Primary Care
The study has two primary aims. The first aim is to assess the efficacy of adding in-person visits to the use of portion-controlled foods for long-term weight loss.
- Trial name
- NCT01220089
- Testing
- Standard maintenance, Intensified maintenance
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
NASH, Fatty Liver
Effects of Online App Weight Loss Programs on Liver Health in Obese Adults
The primary objective of this trial is to assess the effects of online app weight loss programs on liver health in obese adults.
- Conditions
- NASH, Fatty Liver, NAFLD, Weight Loss
- Trial name
- NCT05015491
- Testing
- Noom Healthy Weight Program
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Multicomponent School Based Behavioral Intervention, Prevent Further Weight Gain and or Promote
Team COOL Pilot Study
The goal of this exploratory pilot study was to develop and test the acceptability and feasibility of an innovative alternative high school-based intervention to prevent further weight gain and/or promote weight loss among a…
- Conditions
- Multicomponent School Based Behavioral Intervention, Prevent Further Weight Gain and or Promote, Weight Loss Among Adolescents
- Trial name
- Team COOL (NCT01315743)
- Testing
- Team COOL
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Overweight and Obesity
Efficacy and Safety of Glucosanol™ in Body Weight Reduction
It was proven in a previous clinical study that Glucosanol™ is effective and safe in reducing weight in the overweight and obese.
- Trial name
- NCT02930668
- Testing
- Glucosanol 350mg, Glucosanol 500mg
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Obesity, Weight Loss
Effect of a Protein Intake on Weight Loss of Overweight/Obese Adults
Obesity is considered the epidemic of the 21st century. Obesity is a multifactorial disease and the most important risk factors are poor diet and sedentary lifestyle.
- Conditions
- Obesity, Weight Loss, Protein
- Trial name
- COLABOCO (NCT05368311)
- Testing
- Dietary recommendations including protein enriched bars, Dietary recommendations without protein enriched bars
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obesity
Obesity, Weight Loss, and Cardiovascular Disease Risk
The goal of the study is to define the roles played by resistance to insulin-mediated glucose disposal (insulin resistance) and circulating plasma insulin concentrations in: 1) ability to lose weight; 2) reduction of risk for…
- Trial name
- NCT00186459
- Testing
- Hypocaloric diet of varying macronutrient composition
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Stanford University
Weight Loss
An Examination of a Weight Loss Formula on Health
The aim of this study is to examine a novel weight loss formula with and without common stimulants on anthropometry and indices of cardiovascular disease risk.
- Trial name
- NB14 (NCT03395262)
- Testing
- Active with caffeine, Active without caffeine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Weight Loss, NASH
Phase 1 Study to Evaluate the Safety and Tolerability of VK2735
This is a Phase 1, randomized, double-blind, placebo-controlled single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of VK2735 in healthy adults and…
- Trial name
- NCT05203237
- Testing
- VK2735, VK2735 Drug
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Viking Therapeutics, Inc.
Metabolic Syndrome
Multi-faceted Evaluations Following Weight Reduction in Subjects With Metabolic Syndrome
Central obesity, core of metabolic syndrome, has been recognized as one of the rooting factors for development of diabetes and cardiovascular disease.
- Trial name
- NCT01065753
- Testing
- Lifestyle Counseling
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Hyperglucagonemia, Obesity
Effects of Glucagon Administration on Energy Expenditure
The purpose of this study is to collect data to help researchers better understand the effects of glucagon on the amount of calories burned.
- Trial name
- GLEE (NCT02237053)
- Testing
- Glucagon, Octreotide, Insulin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Infertility
Evaluation of Anti-mullerian Hormone(AMH) Levels as a Predictive Factor of Response to Weight Loss Treatment in Obese Infertile Women With Poly Cystic Ovary(PCOS)
This study is a prospective before \& after clinical trial to compare the basal and 3 months after diet anti-mullerian hormone levels between responders and non-responders to weight loss diet in obese infertile women with PCOS…
- Trial name
- NCT01792362
- Testing
- Weight loss diet
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Obesity
Cognitive Strategies for Weight Loss
The goal of this clinical trial is to compare weight change and other related outcomes associated with three different behavioral weight loss interventions (STANDARD Behavioral, PREVENT, and PROMOTE) in adults with obesity.
- Trial name
- NCT05799846
- Testing
- Standard Behavioral Weight Loss Intervention, PREVENT Behavioral Weight Loss Intervention, PROMOTE Behavioral Weight Loss Intervention
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.