Clinical trials: Weight Reduction
Overweight
Treating Obesity in Underserved Overweight Populations
Obesity has reached epidemic proportions with nearly two-thirds of the US population either overweight or obese. Thus, novel strategies that both improve weight loss maintenance and are accessible to those most in need are the…
- Trial name
- NCT00373230
- Testing
- telemedicine
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Weight Gain
Preventing Obesity in Military Communities, Adolescents
This research study is aimed at the prevention of excessive weight gain in female military dependents at high risk for adult obesity.
- Conditions
- Obesity, Weight Gain, Disordered Eating, Eating Disorder
- Trial name
- POMC-A (NCT02334202)
- Testing
- Interpersonal Psychotherapy-Weight Gain, Health Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Overweight and Obesity
Weight Loss Goals and Satisfaction Survey
The goal of this observational survey pilot study is to learn how 3D visualization tools (i.e., personalized avatars) influence weight loss goals, satisfaction, confidence, and commitment compared to numerical weight outcomes in…
- Trial name
- NCT07541872
- Testing
- Personalized 3D Body Visualization
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Insulin Resistance, Obesity
A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects.
- Trial name
- NCT00398619
- Testing
- INCB13739
- Where
- 2 sites in United States
- Sponsor
- Incyte Corporation
Diabetes, Obesity
Healthy Eating and Active Living Taught at Home
The purpose of this research study is to evaluate two different Parents as Teachers curriculums taught by parent educators, during home visits.
- Trial name
- HEALTH (NCT01567033)
- Testing
- PAT Curriculum + Health Information
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Food Allergen Eliminations and Combined Protocols for Obesity Reduction: a Preliminary Comparison Study
Screened subjects will be tested for hidden food allergies. Subjects will eliminate all food that showed leukocyte reactions for 90-days. Subjects will then also be invited to use the Willis Exercise protocol.
- Trial name
- NCT03821818
- Testing
- Food Allergy Elimination + Willis Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galveston Clinical Research Foundation
Adolescent Mothers, Infant Obesity
Tools For Teen Moms: Reducing Infant Obesity Risk
The purpose of this social media group randomized trial (GRT) is to test the feasibility of our Baby Dayr for Teen Moms intervention to increase maternal responsiveness to infant cues and implement healthy feeding practices…
- Trial name
- TFTM (NCT02244424)
- Testing
- Tools for Teen Moms
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Michigan State University
Obesity
Bone Marrow Adipose Tissue in Relation to Bone and Energy Metabolism in Obesity and Type 2 Diabetes Mellitus
This interventional study is part of a broader research project entitled "Bone Marrow Adipose Tissue in Relation to Bone and Energy Metabolism in Obesity and Type 2 Diabetes Mellitus." The broader project includes both a…
- Trial name
- BOD-BMAT (NCT07731438)
- Testing
- Caloric Restriction
- Where
- 3 sites in Czechia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- General University Hospital, Prague
Nasopharyngeal Carcinoma, Nutritional Support
Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma
Concurrent chemoradiotherapy(CCRT) is the principal treatment for nasopharyngeal carcinoma(NPC). Studies have shown that malnutrition is very common in patients with NPC after chemoradiotherapy.
- Trial name
- NCT04823468
- Testing
- Abbott®Ensure, Intensity Modulated Radiation Therapy, cisplatin
- Where
- 13 sites in China
- Volunteers
- 236 people
- Sponsor
- Jinsheng Hong
Overweight or Obesity
Examination of Circumferential Reduction
The rationale for the selection of Outcome Measures is the compliance with FDA regulations as pertain to medical devices with a moderate level of risk of hazard leading to harm of the patient; firstly, the safety of the device in…
- Trial name
- NCT04451824
- Testing
- CL-100
- Where
- 3 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Contour Research
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity
Effect of a Synbiotic Supplement on a High-protein Diet
The objective of the trial is to study how a synbiotic treatment will affect weight loss and management in individuals enrolled in weight loss diet Profile®.
- Trial name
- NCT03123510
- Testing
- Bifidobacterium spp plus bimuno- galacto-oligosaccharides
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Obesity, Hypertension
Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health
This study will examine the effects of a low carbohydrate diet versus a high carbohydrate diet on weight loss.
- Trial name
- NCT00200720
- Testing
- Atkins diet (low carbohydrate diet), DASH diet (high carbohydrate diet)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Kaiser Permanente
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Overweight and Obesity, Weight Loss
microRNA Testing for Identification of Personalized Weight Management
Certain blood markers are related to one's ability to successfully lose weight by diet and exercise. Currently, the laboratory tests used to measure these blood markers are expensive and time-consuming.
- Trial name
- NCT04217850
- Testing
- 250 kcal Dietary Energy Restriction, Aerobic Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Longevity, GLP-1
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
The goal of this randomized, controlled trial is to evaluate the effectiveness of alternative therapies (metformin alone, with rapamycin, and with low-dose naltrexone) in maintaining weight loss in patients weaning off GLP-1…
- Conditions
- Longevity, GLP-1, Geroscience, Aging
- Trial name
- NCT07092618
- Testing
- Metformin, Rapamycin, Naltrexone
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- AgelessRx
PreDiabetes, Obesity, Morbid
Effectiveness of Dapagliflozin for Weight Loss
Mexico has one of the highest prevalence of obesity, reported on 32.4 percent of people over 20 years old, with a prevalence of obesity class III of 1.8 percent on males and 4.1 percent on females.
- Conditions
- PreDiabetes, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT03968224
- Testing
- Dapagliflozin/Metformin, Metformin
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Centro Medico Nacional Siglo XXI IMSS
Obesity
Multi-Center Pre-Bariatric Weight Loss Study
The purpose of the study is to evaluate the safety and efficacy of the GI Sleeve in patients who require weight loss prior to their Bariatric surgery.
- Trial name
- NCT00469391
- Testing
- GI Sleeve Implantable weight loss device (EndoBarrier)
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Morphic Medical Inc.
Esophageal Cancer, Weight Gain
Resection of the Esophagus and Subsequent Weight Loss
The investigators aim to ascertain how food reward signals and eating behaviour relates to the gut-brain pathway in weight-losing patients after curative surgery for oesophageal cancer, and how this pathway responds to clinical…
- Conditions
- Esophageal Cancer, Weight Gain, Eating Behavior, Food Reward
- Trial name
- REWARD (NCT03377660)
- Testing
- Clinical treatment
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Crohn Disease
Can Intermittent Fasting Induce Weight Loss and Improve Gut Health as Compared to Standard Medical Care in Patients With Obesity/High BMI and Crohn's Disease.
Diet is a determinant of gut microbial diversity and composition and is recognized as a potential environmental trigger for IBD; for example, high-fat diets are associated with increased risk of CD in pre-clinical models, with…
- Trial name
- CD-Fast (NCT05230160)
- Testing
- Intermittent Fasting
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary