Clinical trials: Weight Regain
Obesity and Obesity-related Medical Conditions, Weight Regain
The Application of Gastric Bypass Stents in Patients with Weight Regain After Laparoscopic Sleeve Gastrectomy：a Feasibility Study
This study is based on the National Center for Integrated Traditional Chinese and Western Medicine, utilizing the centralized advantages of our department and integrating multiple disciplines (general surgery, endocrinology…
- Trial name
- DJBL for LSG (NCT06801496)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Obesity
A Study to Characterise the Physiology of Weight Loss and Regain Under Dietary, Behavioural and Pharmacological Interventions in Healthy Obese Subjects
Approximately 60 obese, but otherwise healthy, subjects will be assessed in this benchmark study to investigate the physiological changes associated with weight loss and regain.
- Trial name
- NCT01597609
- Testing
- sibutramine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity Prevention, Bariatric Surgery Complications
Efficacy of Intermittent Fasting Versus Continuous Caloric Restriction in the Treatment of Significant Weight Regain After Bariatric Surgery
Intermittent fasting has gained relevance in recent years because it allows for significant weight loss with improvement in cardiovascular risk factors similar to calorie-restricted diets without people having to track calories…
- Conditions
- Obesity Prevention, Bariatric Surgery Complications, Intermittent Fasting
- Trial name
- NCT06766747
- Testing
- Intermittent Fasting, Continuous calorie restriction
- Where
- Colombia
- Volunteers
- 16 people
- Sponsor
- Hospital Universitario San Ignacio
Dilatation of Anastomosis, Bypass Complication
Carbon Dioxide Versus Air Insufflation for the Application of Argon Plasma to Reduce the Gastrojejunal Anastomosis
The objective of this randomized clinical trial is to compare pain levels during and after insufflation with carbon dioxide or in subjects that will undergo endoscopic fulguration with argon to reduce the diameter of the…
- Conditions
- Dilatation of Anastomosis, Bypass Complication, Obesity
- Trial name
- NCT03264027
- Testing
- Carbon dioxide, Ambient air, Argon fulguration
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Kaiser Clinic and Hospital
Weight Loss, Weight Gain
Role Of Metabolic Adaptation In Weight Regain
In a previous study (NCT04081337), 55 participants with obesity participated on a 18-week lifestyle intervention to reduce their body weight, targeting 10% body weight loss.
- Conditions
- Weight Loss, Weight Gain, Obesity
- Trial name
- EXPEND-FU (NCT05766358)
- Testing
- Intensive lifestyle change therapy, Tirzepatide
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pennington Biomedical Research Center
Bariatric Surgery Candidate
Weight Regain After Bariatric Surgery and Web-Based Interactive Nurse Support Program: Mixed Methods Research
This study was planned to determine the effect of the web-based interactive nurse support program developed in line with the Health Promotion Model on healthy living behaviors and self-efficacy in individuals who gain weight…
- Trial name
- NCT04868279
- Testing
- Web-Based Interactive Nurse Support Program Based on Health Promotion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Cumhuriyet University
Severe Obesity
Resting Metabolic Rate is a Predictor of Weight Regain?
he increasing prevalence of obesity in developed countries has also reached Brazil in the last two decades. Conventional treatments are not efficient to sustained weight loss and in some cases, weight reduction in individuals…
- Trial name
- NCT04118582
- Testing
- Body composition and resting metabolic rate analisys
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Bariatric Surgery Candidate
Efficiency of Using Argon Plasma Coagulation in Weight Regain in Patients Following Gastric Bypass
Among the techniques of bariatric surgery, the gastric Y bypass according to Roux (RYGB) allows greater weight loss and more lasting over time than sleeve gastrectomy and gastric banding.
- Trial name
- ARG-BP (NCT05149105)
- Testing
- Argon plasma coagulation
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Obese Patients With Bariatric Surgery, Obese Patients (BMI ≥ 30 kg/m²)
Interventions for Weight Regain After Bariatric Surgery
Study Objective: The aim of this study is to evaluate the effects of revisional bariatric surgery (RBS), very low-calorie ketogenic diet (VLCKD), and intermittent fasting (IF) on nutritional habits and clinical outcomes…
- Conditions
- Obese Patients With Bariatric Surgery, Obese Patients (BMI ≥ 30 kg/m²), Weight Regain Post Bariatric Surgery, Revisional Bariatric Surgery
- Trial name
- NCT06963437
- Testing
- Diet, Ketogenic diet, Fasting
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Medipol University
Morbid Obesity
Secondary Bypass Banding for Weight Regain or Weight Loss Failure After Lap. Gastric Bypass
This is an observational study on the efficacy of the secondary placement of the A.M.I Soft Gastric Band in weight regain or weight loss failure after lap. gastric bypass.
- Trial name
- NCT01078194
- Testing
- Secondary Bypass Banding (adjustable A.M.I. Soft Gastric Band)
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Obesity
HRS9531 Controls Weight Regain in Obese Subjects
This is a single-center, double-blinded, randomized, placebo-controlled phase II study to explore the effectiveness, safety and energy balance mechanism of low-frequency continuous subcutaneous injection of HRS9531 to inhibit…
- Trial name
- NCT06287437
- Testing
- HRS9531
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai Zhongshan Hospital
Anorexia Nervosa
Impact of Body Schema Distortion on Remission and Weight Regain in Anorexia Nervosa
Anorexia nervosa is a predominantly female eating disorder that most often appears in adolescence. The latter leads to strict and voluntary food deprivation for several months or even years.
- Trial name
- SCAM (NCT05682417)
- Testing
- Body Map Assessment Tool: MOVE Tool, PAQ questionnaire, F-DFlex questionnaire
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hospices Civils de Lyon
Obesity
Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery
This is a randomized, double-blinded, placebo-controlled trial of liraglutide versus placebo over a follow-up period of 12 months in patients at least 18 months following Roux-en-Y gastric bypass (RYGB) who are experiencing…
- Trial name
- NCT03048578
- Testing
- Saxenda
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- NYU Langone Health
Type2 Diabetes
Semaglutide as an Adjunct to Dieting in the Treatment of Type 2 Diabetes
The pharmacological approaches in the treatment of type 2 diabetes (T2DM) have advanced radically during the last decades. However, focus on long-term management of body weight, which is an essential part of treatment success, is…
- Trial name
- MitoSema (NCT04854083)
- Testing
- Semaglutide, 1.34 mg/mL
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Kirsi Pietiläinen
Obesity
Time-Restricted Eating as a Potential Strategy to Promote Weight Loss Maintenance in Patients With Obesity
While body weight reduction can be achieved through various interventions in people living with obesity, most patients regain a substantial proportion of the lost weight within the following months.
- Trial name
- REGANE (NCT07315659)
- Testing
- Calorie restriction (Dietary intervention), Regular eating window, Time-restricted eating
- Where
- Spain
- Volunteers
- 212 people
- Sponsor
- Universidad de Granada
Obesity
Mindfulness and Compassion-based Programs on Food Behavior of Patients With Weight Regain After Bariatric Surgery
Weight regain in patients after bariatric surgery has been reported as one of the main failure factors of these surgeries, has important health consequences, such as the return of associated comorbidities, and, until that moment…
- Trial name
- NCT04171713
- Testing
- Mindfulness-Based Health Promotion + Treatment as usual, Attachment-based compassion therapy + Treatment as usual, Treatment as usual
- Where
- Brazil
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
Obesity
A Study of MK0364 in Obese Patients (0364-014)
A worldwide study in obese patients to assess the efficacy, safety, and tolerability of an investigational drug.
- Trial name
- NCT00131391
- Testing
- Comparator: taranabant
- Volunteers
- 2,400 people
- Sponsor
- Merck Sharp & Dohme LLC
Overweight or Obesity
Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain
This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Participants will be randomly assigned to one of two conditions.
- Trial name
- Momentum (NCT07708064)
- Testing
- JITAI Combined with psychological intervention, Active Control
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- ORI Community and Evaluation Services
Obesity
Adaptive Responses to Overfeeding and Weight
To more effectively address the problem of weight regain following weight loss for obese individuals, this study will evaluate the underlying biology of the reduced obese state.
- Trial name
- ARrOW (NCT03857048)
- Testing
- Weight Loss, Exercise training, Overfeeding
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Weight Gain
Role of Dairy Products in Weight Maintenance
The goal of the current study is to determine the role of dairy in similarly preventing weight and fat re-gain in obese adults who have successfully completed a weight loss diet program.240 obese subjects will undergo a…
- Trial name
- NCT00686426
- Testing
- Dairy Foods
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Tennessee