Clinical trials: Well Aging
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Aging, Healthy
Healthy Aging Through Dietary Intervention
To test the impact of flavanol supplementation of cardiac and vascular function and subsequently on exercise capacity in elderly individuals
- Trial name
- NCT05782309
- Testing
- Flavanol
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Mild Cognitive Impairment, Healthy Aging
Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition
Impaired working memory (WM) plays a crucial role in normal aging, in mild cognitive impairment (MCI) and cognitive decline associated with dementia, such as Alzheimer's disease (AD).
- Trial name
- NiBS-iCog (NCT04986787)
- Testing
- tACS, TMS, TIS
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Aging
Bloodflow Restricted Exercise in Healthy Ageing
The overall objective of this study is to investigate the efficacy of low-intensity blood flow restricted resistance exercise (BFRRE) to promote health beneficial skeletal muscle adaptations and augment muscle function in a…
- Trial name
- NCT04712955
- Testing
- Bloodflow restricted exercise
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy Aging, Healthy
The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots
Open labelled, virtual home based study to assess the test repeatability and the failure/rejection rate of the samples collected at home by participants.
- Conditions
- Healthy Aging, Healthy, Healthy Diet
- Trial name
- NCT04985630
- Testing
- Mitopure, Pomegranate Juice
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Well Aging
Mindfulness Training for Seniors
The purpose of this research study is to learn more about how mindfulness training may influence thinking and feeling.
- Trial name
- NCT04378803
- Testing
- Mindfulness training (MT) Connect
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy Volunteers
Metabolism of Omega-3 and Omega-6 During Healthy Aging
The purpose of this study is to determine the kinetics of 13C-eicosapentaenoic acid (EPA) and 13C-arachidonic acid (AA) in young and older participants
- Trial name
- NCT02957188
- Testing
- 13C eicosapentaenoic acid and 13C arachidonic acid
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Joint Pain
Move Study in Healthy Aging People
Bone and muscle losses occur during ageing leading to increased risk of osteoporosis (there are more than 200 million people affected by osteoporosis worldwide), sarcopenia, loss of functionality and mobility.
- Trial name
- NCT02276183
- Testing
- Nutrition intervention, test formula, progressive physical activity
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Exercise Adherence, Healthy Aging
Effectiveness of a Smartphone Chatbot to Improve Exercise Adherence in Older Adults
This randomized controlled trial aims to evaluate the effectiveness of a smartphone-based chatbot in improving adherence to a 12-week home-based multicomponent exercise program in community-dwelling older adults.
- Trial name
- EXEBOT (NCT07832097)
- Testing
- Chatbot-Supported Home-Based Exercise Program, Paper-Based Home Exercise Program Mostrar más líneas
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Sleep
Sleep-dependent Learning in Aging
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both.
- Trial name
- NCT03840083
- Testing
- Sleep
- Where
- United States
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Cardiovascular Diseases, Non-communicable Disease
Effects of Primary Prevention in Elderly People-The Healthy Aging Initiative
The number of elderly will increase rapidly in Europe in the next 30 years, which affects the country's economic and social development, welfare, health care, and also the individuals.
- Trial name
- HAI (NCT03312439)
- Testing
- Given advice
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Region Västerbotten
Aging Well
Immersive Technology and Virtual Reality as a Health Support Tool in a Residence for the Elderly
The purpose of this clinical trial is to learn more about the potential for using virtual reality in older adults living in residences for elderly to maintain health (physical activity, cognitive activity, social behaviors).
- Trial name
- NCT06117319
- Testing
- Individual assistance Virtual reality training sessions, Collective assistance Virtual reality training sessions
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TOPMED
Healthy Aging
Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise
This study is a validation study to evaluate efficacy of a neuroplasticity-based, computerized cognitive training program INHANCE (Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise) to improve…
- Trial name
- INHANCE (NCT04149457)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Healthy Aging
Effects of Different Moderate-intensity Exercise Methods on Health in the Elderly
Aging is linked to a higher risk of cardiovascular disease. Physical exercise is recognized as an excellent strategy to prevent cardiovascular diseases and cognitive aspects, generating healthier elderly people.
- Trial name
- 4MIIT (NCT05207501)
- Testing
- Exercise
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Family Caregiver
Circle Dance for Family Caregivers of the Elderly With Alzheimer.
The primary objective of this research is to compare the effects of a 12-week CircleCare on physical functioning of family caregivers of the elderly with AD.
- Trial name
- CircleCare (NCT03081533)
- Testing
- Circle Dance Program (CircleCare)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Healthy Aging
Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Executive control processes involve initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT05506852
- Testing
- Web-based training strategy, Web-based regular training (no strategy)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Aging Well, Nursing Caries
Effect of Mindfulness- Based Stress Reduction Program in the Elderly onSpiritual Well- Being and Meaning of Life
This quasi-experimental study with a pretest-posttest control group will be conducted to determine the effect of a mindfulness-based stress reduction program on spiritual well-being and the meaning of life among the elderly.
- Trial name
- NCT06712056
- Testing
- Mindfulness
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Psychological Well-being, Nursing Homes Residents
Effects of Exergaming and Autogenic Relaxation on Psychological Well-Being in Nursing Home Residents
This interventional clinical trial was conducted to evaluate the effects of Antroyun (exergaming) and autogenic relaxation techniques on psychological well-being and life engagement among older adults living in nursing homes.
- Conditions
- Psychological Well-being, Nursing Homes Residents, Aging, Exergaming
- Trial name
- NCT06965959
- Testing
- Exergaming Intervention Group, Autogenic Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University