Clinical trials: Well-being
Sickle Cell Disease
Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease
SCD is an inherited disorder of hemoglobin that affects over 100,000 Americans, most of whom live in low-resourced neighborhoods.
- Trial name
- NCT03629678
- Testing
- mobile health application
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Psoriasis
Observational Study Evaluating Etanercept (Enbrel®) In Subjects With Plaque-Type Psoriasis In Usual Care Settings
This prospective observational cohort study will assess the average duration of the drug free interval between etanercept treatment cycles in usual care settings in Germany.
- Trial name
- NCT00708708
- Testing
- etanercept (Enbrel®)
- Where
- Germany
- Volunteers
- 926 people
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
A Pilot Study of Danirixin for Disease Progression in Chronic Obstructive Pulmonary Disease (COPD)
This is a pilot study to investigate the effect of danirixin hydrobromide 35 milligram (mg) tablets on lung function and health related quality of life (HRQoL) in subjects with mild to moderate airflow obstruction and a…
- Trial name
- NCT03170232
- Testing
- Danirixin 35 mg tablets, Metered dose inhaler (MDI) sensor device, Rescue medication
- Where
- 11 sites in United States
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
School Board Health Centers
Feasibility Study on the Model School Pediatric Health Initiative Pilot Project
This is a prospective cross sectional study to assess the feasibility of a school based health centre (SBHC) at Sprucecourt Public School, an inner-city elementary school in Toronto.
- Trial name
- NCT01676532
- Testing
- Students attending SBHC
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Stress, Carer Stress Syndrome
Tailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With Dementia
How do different health self-management interventions (resourcefulness training or biofeedback training) compare to usual care (dementia education) in affecting the health risks, and physical and mental health, of family…
- Conditions
- Stress, Carer Stress Syndrome, Dementia, Alzheimer Disease
- Trial name
- NCT04247347
- Testing
- Biofeedback Training, Dementia Education, Resourcefulness Training
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Retraction of Colostomy
A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly reducing total…
- Trial name
- IMPROVE-IR (NCT01509638)
- Testing
- Group 1 Standard of Care, Group 2 EXPAREL
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pregnancy, Smoking
Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
Our goal is to study self-monitoring of smoking as a means to reduce smoking in pregnant women. Investigators hypothesize that more regular self-monitoring, text messages and feedback as provided by home carbon monoxide…
- Conditions
- Pregnancy, Smoking, Smoking Cessation
- Trial name
- NCT02246114
- Testing
- piCO+ Smokerlyzer® monitor, Text messages
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
HIV Testing, Contraceptive Usage
Adolescent Wellness Visits in Tanzania
This study evaluates the impact of clinic-based 'Adolescent Wellness Visits' (AWVs) coordinated with primary schools that offer a package of evidence-based adolescent-friendly preventative services on HIV testing uptake in…
- Trial name
- VITAA (NCT05306938)
- Testing
- Adolescent Wellness Visit
- Where
- Tanzania
- Volunteers
- 1,095 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Low Back Pain, Lumbago
Validation of the STarT Back Screening Tool in the Military
This is a trial to validate the use of the STarT Back Screening Tool (SBST) in the Military Health System for patients with low back pain presenting to primary care.
- Conditions
- Low Back Pain, Lumbago, Radiculopathy, Intervertebral Disc Disorder
- Trial name
- NCT03127826
- Testing
- Risk Stratified Care, Usual Care
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Brooke Army Medical Center
Nicotine Dependence
Extended Varenicline Treatment for Smoking Among Cancer Patients
Upwards of 33-50% of cancer patients who smoked prior to diagnosis continue to smoke following diagnosis and treatment. With medical advances in cancer care yielding a growing constituency of cancer survivors, addressing nicotine…
- Trial name
- NCT01756885
- Testing
- Varenicline, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 207 people
- Sponsor
- University of Pennsylvania
Patient Adherence, HIV Seronegativity
CCTG 595: Text Messaging Intervention to Improve Adherence to PrEP in High-risk MSM
CCTG 595 is a controlled, open-label, two-arm, randomized (1:1) clinical demonstration project to determine if the use of a text-message based adherence intervention (iTAB) improves retention and adherence to PrEP compared to…
- Trial name
- NCT01761643
- Testing
- SoC + iTab
- Where
- 4 sites in United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sexual Behavior
Young Men and Media Study
Adolescent sexual minority males (ASMM) continue to account for a disproportionate number of HIV infections in the United States. Racial and ethnic minority populations are particularly affected.
- Trial name
- NCT04109443
- Testing
- Young Men & Media Program, Available websites on safe sex and preventing STIs
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Smoking Cessation
Comparison of Pharmacokinetic Profiles of Two Nicotine Gum Formulations
The primary objective of this study is to compare pharmacokinetic (PK) profiles and assess the bioequivalence between the newly developed nicotine gums (2 mg and 4 mg) and the reference nicotine gums (2 mg and 4 mg) in healthy…
- Trial name
- NCT01847443
- Testing
- Nicotine (2 mg), Nicotine (4 mg)
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV/AIDS
Community Health Worker And MHealth to ImProve Viral Suppression
The overall goal of this study is to evaluate the effects of the CHAMPS intervention for people living with HIV (PLWH) in a randomized controlled trial.
- Trial name
- CHAMPS (NCT04562649)
- Testing
- Wise App with medication adherence reminders, CHW Sessions
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Columbia University
Healthy Children (1 Month to 17 Years Old)
Capillary Refill Time Measurement Utilizing Mobile Application in Children
To determine the accuracy and precision of capillary refill time measurement using a mobile health application (Cap App) in a healthy pediatric population.
- Trial name
- CapApp (NCT05472116)
- Testing
- Mobile Health application (CapApp)
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Reproductive Health
Youth-friendly Sexual and Reproductive Healthcare Pilot in Mumbai, India
This study will systematically adapt, pilot test, and evaluate an integrated community/facility intervention to improve the uptake of adolescent-friendly services for married and unmarried adolescent girls and young women (AGYW…
- Trial name
- NCT04307849
- Testing
- Adolescent Health Club, Wait-list Control
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Schizophrenia, Smoking Cessation
Varenicline and Smoking Cessation in Schizophrenia
There is a strong association between smoking and schizophrenia with prevalence rates ranging from 74% to 90%, versus a national average of 30% in nonschizophrenic individuals.
- Trial name
- VSCS (NCT01111149)
- Testing
- Sugar Pill, Varenicline, Bupropion HCl
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Cerebrovascular Accident
Home-based Telehealth Stroke Care: A Randomized Trial for Veterans
The purpose of the proposed study is to examine a Tele-rehabilitation (TR) intervention that uses tele-health technology to improve outcomes of stroke patients after discharge to home.
- Trial name
- NCT00384748
- Testing
- TR intervention, In-home messaging device., Usual care
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Major Depressive Disorder
Phase IV:Safety and Efficacy of EMSAM in Adolescents With Major Depression
The primary purpose of your participation in this study is to help answer the following research question: Whether 12-week administration of EMSAM (selegiline transdermal system) is safe and effective for the treatment of…
- Trial name
- NCT00531947
- Testing
- Selegiline Transdermal System
- Where
- 20 sites in United States
- Volunteers
- 308 people
- Sponsor
- Somerset Pharmaceuticals
Heart Failure
A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
The purpose of this study is to determine the superiority of the effectiveness of canagliflozin 100 milligram (mg) daily versus placebo in participants with symptomatic heart failure (HF) in improving the overall Kansas City…
- Trial name
- CHIEF-HF (NCT04252287)
- Testing
- Canagliflozin 100 mg
- Where
- 18 sites in United States
- Volunteers
- 476 people
- Sponsor
- Janssen Research & Development, LLC
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