Clinical trials: Well-being
Data Accuracy, Agency
Empowerment Training for Personal Agency Development of Primary Health Care Workers
This study evaluates an Empowerment Agency Training (EAT) intervention within the SPHERES programme that aims to strengthen personal agency among workers in primary healthcare centers (Puskesmas) in Indonesia.
- Conditions
- Data Accuracy, Agency, Burnout, Service Evaluation
- Trial name
- NCT07509931
- Testing
- Empowerment Agency Training (EAT)
- Where
- 2 sites in Indonesia
- Volunteers
- 200 people
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Obesity, Vitamin D Deficiency
Vitamin D and Vascular Health in Children
In this study, we will test the central hypothesis that enhancement of vitamin D status in obese and overweight children will improve their vascular health and their cardiovascular disease (CVD) and metabolic syndrome risk…
- Trial name
- NCT01797302
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer, Physical Activity
Physical Activity Platform to Improve Bone Health in Cancer Survivors
Cancer treatment-induced bone loss and the subsequent risk of fractures in both men and women impacts not just survivors' quality of life, but is also a significant burden on national health care.
- Conditions
- Breast Cancer, Physical Activity, Bone Health
- Trial name
- THRIVORS+BH (NCT03651037)
- Testing
- Thrivors+BH
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Thrivors Inc
Under Five Child Health Nutrition and Immunization
Naunehal - Integrated Immunization & MNCH Interventions; A Quasi-Experimental Study
Maternal, newborn, and child health (MNCH) are an area of concern in Pakistan with many health and nutrition indicators at sub-optimal levels.
- Trial name
- NCT05135637
- Testing
- Mobile health services, Private practitioner engagement for immunization, Community engagement and mobilization
- Where
- Pakistan
- Volunteers
- 8,100 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Health Care Utilization
A Pilot Study Efficiency of Techniques of 'Snail ' and 'Go-back' Application of an Alcoholic Antiseptic on Healthy Skin Before the Placement of a Intra-vascular Device,
Given the lack of scientific data on the effect of the antiseptic application technique on reducing the number of microorganisms present during application, this pilot study will provide data on the initial level of…
- Trial name
- TApAS (NCT04002245)
- Testing
- antiseptic application
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Cervical Cancer Screening, Gynecologic Cancers
Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India
This is a combination of retrospective and prospective observational study that will be performed across NCG and other participating centers to report compliance to chemoradiation for cervical cancer.
- Conditions
- Cervical Cancer Screening, Gynecologic Cancers, Treatment Compliance, Chemoradiotherapy
- Trial name
- NCG-Compliance (NCT07290972)
- Testing
- Not applicable- observational study
- Where
- 2 sites in India
- Volunteers
- 618 people
- Sponsor
- Tata Memorial Hospital
Personality, Patient Satisfaction
Impact of Personality on Satisfaction Following Presbyopic Correction
Primary objective of this study is the exploration of the impact of personality type, social roles and working mandates οn the visual capacity and satisfaction of patients that underwent pseudophakic presbyopic correction.
- Conditions
- Personality, Patient Satisfaction, Presbyopia
- Trial name
- NCT05191329
- Testing
- TPQue Greek version, NEI-VFQ-25 Greek version
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Subjective Cognitive Concerns, Mild Cognitive Impairment
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
The goal of this study is to objectively test one's sense of smell, called olfaction, in participants with Subjective Cognitive Concerns (SCC), Mild Cognitive Impairment, Mild Behavioral Impairment (MBI), and age-matched…
- Conditions
- Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
- Trial name
- NCT05881239
- Testing
- AROMHA Brain Health Test
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Acute Care Service Utilization, Mental Health Status
Homeless Veterans and Peer Whole Health Coaching
Use of acute care services (e.g., hospitalizations, Emergency Department visits) contributes substantially to the cost of healthcare for Veterans. Homelessness is a robust social determinant of super utilization of acute care.
- Conditions
- Acute Care Service Utilization, Mental Health Status, Physical Health Status, Housing
- Trial name
- PWHC (NCT05176977)
- Testing
- Peer Support-Whole Health Coaching
- Where
- 3 sites in United States
- Volunteers
- 177 people
- Sponsor
- VA Office of Research and Development
Pregnancy, Sexually Transmitted Diseases
Development and Testing of a Clinic-Based Intervention to Increase Dual Protection Against Unintended Pregnancy and Sexually Transmitted Diseases (STDs) Among High Risk Female Teens
This trial will evaluate a multi-component, clinic-based intervention aimed at increasing dual protection strategy selection and adherence among young African American females at an urban family planning clinic.
- Trial name
- 2Gether (NCT02291224)
- Testing
- Interactive multimedia platform, Intervention arm counseling, Standard of care counseling
- Where
- United States
- Volunteers
- 709 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Coronary Heart Disease
Exercise and Brain in Coronary Heart Disease
The Heart-Brain project is a randomized controlled trial designed to examine the effects of two different exercise programs of 12-week duration: 1) aerobic high intensity interval training (HIIT), and 2) aerobic HIIT plus…
- Trial name
- Heart-Brain (NCT06214624)
- Testing
- Two types of exercise interventions
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Universidad de Granada
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Preconception Health
Involving Communities in Addressing the Maternal Health Crisis: Making an IMPACT
With support from the National Heart, Lung, and Blood Institute, The Center for Maternal Health Equity at Morehouse School of Medicine is conducting a research study to test the implementation of Pre-Pregnancy Counseling in…
- Trial name
- Project IMPACT (NCT05987059)
- Testing
- SBIRT Intervention
- Where
- 2 sites in United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Physical Activity, Exercise Training
Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity
This multicentre two-phased RCT aims to evaluate implementation potential, cost-effectiveness, effectiveness, and the role of exercise intensity of a home-based exercise and physical activity intervention to improve de novo…
- Conditions
- Physical Activity, Exercise Training, Kidney Transplantation, Physical Fitness
- Trial name
- PHOENIX-Kidney (NCT06260579)
- Testing
- Exercise/physical activity
- Where
- 2 sites in Belgium
- Volunteers
- 147 people
- Sponsor
- KU Leuven
Hypertension (HTN), Preeclampsia
Mobile Health Program for Post-Preeclampsia Hypertension
Strategies targeted to optimize hypertension (HTN) control for midlife women after hypertensive disorders of pregnancy (HDP) have not been studied, despite evidence of a critical need.
- Conditions
- Hypertension (HTN), Preeclampsia, Hypertensive Disorders of Pregnancy (HDP)
- Trial name
- NCT07599579
- Testing
- Coaching application, Home-based blood pressure monitoring, WebMD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Eosinophilic Granulomatosis With Polyangiitis (EGPA), Churg-Strauss Syndrome (CSS)
Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis
Naltrexone is an FDA approved drug (for alcoholism) that has found widespread use "off-label" to treat pain and improve quality of life at much lower doses than are used for the approved indication.
- Conditions
- Eosinophilic Granulomatosis With Polyangiitis (EGPA), Churg-Strauss Syndrome (CSS), Giant Cell Arteritis, Granulomatosis With Polyangiitis
- Trial name
- LoDoNaVasc (NCT03482479)
- Testing
- Naltrexone Hydrochloride
- Where
- 7 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Influenza
Hutterite Influenza Prevention Study
The goal of this randomized clinical trial is to determine whether immunizing children in Hutterite colonies with inactivated influenza vaccine can prevent influenza and its complications in other colony members.
- Trial name
- NCT00877396
- Testing
- Influenza vaccination, Hepatitis A Vaccine
- Volunteers
- 4,771 people, healthy volunteers welcome
- Sponsor
- McMaster University
SARS CoV 2 Infection, RSV Infections
Expression of Inflammatory Markers in the Course of Acute Respiratory Viral Infections
Respiratory viral infections caused by influenza, respiratory syncytial virus (RSV), and SARS-CoV-2 remain major causes of morbidity, hospitalization, and mortality among older adults worldwide.
- Conditions
- SARS CoV 2 Infection, RSV Infections, Influenza Infection
- Trial name
- AIRE-INT (NCT07643688)
- Volunteers
- 150 people
- Sponsor
- Fabiana Sherine Ganem dos Santos
Fever, Anxiety
LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System
The positive effects of fever are supported by a number of physiological, pathophysiological and clinical evidence. However, the negative attitude toward fever is widespread and have become persistent.
- Conditions
- Fever, Anxiety, Help-Seeking Behavior, Virus Diseases
- Trial name
- NCT04633603
- Testing
- FeverFriend mobile application
- Where
- Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Pecs