Clinical trials: Whiplash Injury
Central Sensitisation, Fibromyalgia
The Nociceptive Flexion Reflex as a Diagnostic Tool of Central Sensitization
This experimental study will investigate whether the decreased NFR threshold and increased NFR temporal summation, which are frequently observed in chronic pain patients, are only symptomatic manifestations that occur in the…
- Conditions
- Central Sensitisation, Fibromyalgia, Neck Pain, Low Back Pain
- Trial name
- NFR-CS (NCT05321550)
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Ghent
Whiplash Injury of Cervical Spine
Rehabilitation for Whiplash Associated Disorders
Individuals (n=180) with subacute (<1 month, >3 months) WAD grade I and II with medium to high-risk symptoms of working age will be randomized into three groups with block randomization in a prospective, assessor-blinded…
- Trial name
- NCT05319808
- Testing
- Manual therapy, Telehealth exercises, Non-computer based exercises
- Where
- 4 sites in Iceland
- Volunteers
- 180 people
- Sponsor
- University of Iceland
Whiplash Associated Disorder
Cervical Plexus Block (CPB) in Whiplash Associated Disorder (WAD)
Whiplash is the most common injury associated with motor vehicle accidents and a major cause of disability and litigation. An acute whiplash injury follows sudden or excessive hyperextension, hyper flexion, or rotation of the…
- Trial name
- NCT04622020
- Testing
- Cervical Plexus Block with Local Anaesthesia, Cervical Plexus Block with Depot Steroids
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospitals, Leicester
Whiplash Injuries
Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders
The knowledge of pathophysiological mechanisms behind prolonged Whiplash Associated Disorders (WAD) is insufficient and whether changes can be restored by rehabilitation or not is unknown.
- Trial name
- NCT03664934
- Testing
- Exercises
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Whiplash, Healthy
The Effect of Adding Auditory Information on Head Movements in People With Traumatic Neck Pain
This study sets out to investigate the potential effect of auditory disturbances on human movement
- Trial name
- NCT06028308
- Testing
- Smartphone playing a sound
- Where
- 2 sites in Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Whiplash Injury of Cervical Spine
The Efficacy and Safety of Non-resistance Manual Therapy in Inpatients With Acute Neck Pain Caused by Traffic Accidents: a Randomised Controlled Trial
Non-resistance therapy is a combination of muscle compression relaxation technique and joint mobilization in patients with acute neck pain caused by traffic accidents.
- Trial name
- NCT04660175
- Testing
- non-resistance therapy, acupuncture, chuna
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Jaseng Medical Foundation
Whiplash
Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders
Modern pain neuroscience has advanced our understanding of chronic whiplash associated disorders (WAD). Previous studies have shown the importance of central sensitization, characterized by hypersensitivity of the somatosensory…
- Trial name
- NCT03239938
- Testing
- Modern pain neuroscience approach, Usual care evidence-based physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Vrije Universiteit Brussel
Whiplash Injuries
Shifting Away From Pain: a Neurocognitive Approach in Treatment of Whiplash
The broad aim of this study is to investigate the effect of a modern neuroscience approach, which combines education on pain neuroscience with cognition-targeted exercise therapy and stress management, on brain structure and…
- Trial name
- NCT04077619
- Testing
- Modern pain neuroscience approach, Usual care physiotherapy
- Where
- Belgium
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Ghent
Post-Concussion Syndrome, Mild Traumatic Brain Injury
Cervico-vestibular Rehabilitation for Mild Traumatic Brain Injury
Neck pain, dizziness and headache are common symptoms following mild traumatic brain injury (mTBI). The efficacy of cervical spine and vestibular-ocular system impairments intervention need to be determined.
- Conditions
- Post-Concussion Syndrome, Mild Traumatic Brain Injury, Vestibular Disorder, Whiplash Injuries
- Trial name
- NCT03677661
- Testing
- Conventional approach, Personalized rehabilitation program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Whiplash Injuries
Neuroinflammation as a Predictor of Chronicity in Whiplash
Whiplash describes an injury to the neck caused by a rapid movement of the head. It often occurs during a motor vehicle collision, causing considerable pain and distress.
- Trial name
- NCT04940923
- Testing
- MRI
- Where
- 2 sites in United Kingdom
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Thoracic Outlet Syndrome, Whiplash Injuries
Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin.
Whiplash injuries following car accident are common, it has been reported to affect 83% of individuals injured in traffic collisions (Yadla S, 2007).
- Trial name
- NCT05536570
- Testing
- IncobotulinumtoxinA 100 UNT
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- King, David, MD
Accidents, Traffic, Whiplash Injuries
The Analysis for Termination of Treatment and Satisfaction in Traffic Accident Patient
Data of one hospital will be used to find out the patient's satisfaction with the treatment, analyze the factors effecting on the treatment termination.
- Trial name
- NCT04167930
- Testing
- electronic medical record(EMR) Data and patient survey
- Where
- 2 sites in South Korea
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Neck Pain, Whiplash
PROCO Neck: The Course and Neuroplasticity in Neck Pain-Associated Disorders and Whiplash-Associated Disorders
Neck pain-associated disorders (NAD) and whiplash-associated disorders (WAD) are major health problems. NAD has a lifetime prevalence of 54%.
- Conditions
- Neck Pain, Whiplash, Pain, Acute, Psychosocial Functioning
- Trial name
- NCT05468684
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 168 people
- Sponsor
- University of applied sciences
Whiplash Injuries, Neck Injuries
Effectiveness of Physiotherapy Following PRP for Chronic Whiplash
The investigators will explore a standardized and previously published evidence-based conservative multimodal physiotherapy treatment fulfilling clinical practice guidelines in individuals with chronic whiplash-associated…
- Conditions
- Whiplash Injuries, Neck Injuries, Platelet Rich Plasma
- Trial name
- NCT03949959
- Testing
- Multimodal physiotherapy
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of Calgary
Whiplash
Chronic Whiplash Associated Disorders: Disability, Pain (Beliefs), Central Sensitization and Brain Activity
This is a cross-sectional case-control study in which 70 patients with chronic whiplash associated disorders will be recruited and compared to 70 healthy pain-free controls.
- Trial name
- NCT04204525
- Testing
- Quantitative sensory testing
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- University Ghent
Cervical Facet Joint Pain
Treatment for Whiplash Injury
Objective: Cervical facet joint (CFJ) pain is commonly seen after whiplash injuries, and is frequently refractory to physical therapy and oral medication.
- Trial name
- NCT04959721
- Testing
- Injection with triamcinolone acetonide, bupivacaine, and normal saline
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Min Cheol Chang
Musculoskeletal Disorders, Whiplash
Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders
The purpose of this study is to determine whether a specifically tailored value-based cognitive behavioural therapy program (V-CBT) is able to prevent the development of persistent disability, pain, and psychological distress if…
- Trial name
- NCT02251028
- Testing
- Value-based cognitive-behavioral therapy
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Southern Denmark
Whiplash, Whiplash Injury
Changes of Pain Sensitivity During Rehabilitation of Patients Suffering From Whiplash Associated Disorders
This study investigates the sensory profile of people suffering from whiplash associated disorders (WAD) during rehabilitation.
- Conditions
- Whiplash, Whiplash Injury, Neck Pain, Healthy
- Trial name
- NCT03784196
- Testing
- Conservative rehabilitation
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Whiplash Injuries
Efficacy of the Use of Dry Needling in Conventional Non-invasive Treatment of Acute and Subacute Whiplash
INTRODUCTION: Whiplash is an injury produced by an acceleration-deceleration mechanism that transmits energy to the cervical spine.
- Trial name
- NCT03502928
- Testing
- Motor Control, Manual Therapy, Dry Needling
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Alcala
Whiplash Injuries
Is Chronic Whiplash-associated Pain of Neurogenic Origin?
The purpose of this study is to compare the effects of neurolysis with the effects of a exercise program on pain and other symptoms in individuals with chronic whiplash (WAD II-III).
- Trial name
- NCT02692937
- Testing
- Neurolysis, Traditional neck-specific exercise program
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane