Clinical trials: Whipple Procedure
Pancreatic Ductal Adenocarcinoma
Should a Standard Lymphadenectomy Include the No. 16 Lymph Nodes for Patients With Pancreatic Head Adenocarcinoma.
The aim of this study is to determine whether para-aortic lymph nodes(No.16) should be included in the lymphadenectomy during the pancreatoduodenectomy in order to improve the long-term survival of patients with pancreatic head…
- Trial name
- NCT04115527
- Testing
- Extended Lymphadenectomy, Standard Lymphadenectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
Patients Who Undergo Pancreatoduodenectomy
Horizontal Mattress vs. Interrupted Suture in Surgical Techniques of Pancreaticojejunostomy
The aim of this study is to verify that the frequency of pancreatic fistula (ISGPF grade B and C) in horizontal mattress suture are lower than in interrupted suture during pancreaticojejunostomy in pancreatoduodenectomy by…
- Trial name
- NCT01898780
- Testing
- pancreaticojejunostomy with horizontal mattress suture, pancreaticojejunostomy with interrupted suture
- Where
- Japan
- Volunteers
- 190 people
- Sponsor
- Wakayama Medical University
Pancreatic Cancer, Malnutrition
Whipple Protein Study
Study investigators aim to assess the effect of providing high-protein nutritional supplementation before and after surgery
- Trial name
- WPS (NCT04306874)
- Testing
- Ensure Max Protein
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Thomas Jefferson University
Pancreatic Cancer, Anemia
Efficacy of Ferric Carboxymaltose (Ferinject®) in Anemic Patients Anticipating Pancreatoduodenectomy
This phase II study is to evaluate the safety and efficacy of Ferinject® in reducing perioperative transfusion in iron deficiency anemia patients anticipating pancreatoduodenectomy.
- Trial name
- FCM (NCT02628860)
- Testing
- Ferinject (Ferric Carboxymaltose)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- National Cancer Center, Korea
Morbidity, Celiac Axis Stenosis
The Effect of Celiac Axis Stenosis on Morbidity After Pancreatoduodenectomy - A Prospective Study
The association between celiac axis stenosis and morbidity after pancreaticoduodenectomy is the primary focus of the study.
- Conditions
- Morbidity, Celiac Axis Stenosis, Pancreaticoduodenectomy, Pancreatic Cancer
- Trial name
- NCT07412301
- Where
- Greece
- Volunteers
- 99 people
- Sponsor
- Larissa University Hospital
Periampullary Tumors
Impact of Prophylactic Octreotide to Pancreatic Exocrine Secretion
This study aims to examine whether octreotide has an effect on inhibition of the exocrine secretion fo the pancreas, which might lower the rate of postoperative pancreatic fistula after pancreatoduodenectomy.
- Trial name
- NCT02920567
- Testing
- Octreotide
- Where
- South Korea
- Volunteers
- 282 people
- Sponsor
- Saint Vincent's Hospital, Korea
Pancreaticoduodenal; Fistula, Surgery Timing
Effects of Surgical Timing on Perioperative Clinical Outcomes in Pancreaticoduodenectomy
With the advancement of surgical techniques and the increase in pancreatic oncologic diseases, the volume of pancreaticoduodenal surgeries has been increasing year by year in our center, and multiple pancreaticoduodenal surgeries…
- Conditions
- Pancreaticoduodenal; Fistula, Surgery Timing, Perioperative Complication
- Trial name
- NCT06874660
- Where
- China
- Volunteers
- 350 people
- Sponsor
- West China Hospital
Pancreatic Fistula, Whipple Operation
Identifing Risk Factors for Pancreaticojejunostomy Leakage Following Pancreaticoduodenectomy
Pancreatic cancer is an aggresive type of cancer with poor mean survival rates despite improvements in chemotherapy regimens and advances in surgical techniques. Surgery is the only therapeutic option with an intend to treat.
- Conditions
- Pancreatic Fistula, Whipple Operation, Pancreaticoduodenectomy, POPF
- Trial name
- NCT04798560
- Testing
- Pancreaticoduodenectomy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Dimitrios Vouros
Post Operative Pancreatic Fistula
Predictors of Severity of Postoperative Pancreatic Fistula After Pancreatoduodenectomy
Pancreaticoduodenectomy is one of the commonly performed procedure for periampullary carcinoma/distal cholangio carcinoma/head of pancreas carcinoma.
- Trial name
- NCT05291923
- Testing
- no intervention
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Pancreatic Tumor, Bile Duct Tumor
Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
The purpose of this study is to investigate whether perioperative immunonutrition has additional effects on cell-mediated immunity in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT01969110
- Testing
- Oral IMPACT
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Chiba University
Pancreas Disease, Fistula Pancreatic
Prevention of CR-POPF in PD With the Technique of Connexion the Pancreatic Duct to Jejunum Stented (CONDUCTJE-ST).
Objective: To assess the efficacy of the "connexion pancreatic duct to jejunum stented (CONDUCTJE-ST)" technique to prevent clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreaticoduodenectomy (PD).
- Trial name
- CONDUCTJE-ST (NCT04898517)
- Testing
- Pancreaticoduodenectomy with the CONDUCTJE-ST technique
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Carcinoma, Pancreatic Ductal
Standard Versus Extended Lymphadenectomy in Pancreatoduodenectomy for Patients With Pancreatic Head Adenocarcinoma
The aim of this study is to determine whether the performance of extended lymphadenectomy in association with pancreatoduodenectomy improves the long-term survival in patients with pancreatic head ductal adenocarcinoma.Half of…
- Trial name
- NCT02928081
- Testing
- Extended lymphadenectomy, Standard lymphadenectomy
- Where
- China
- Volunteers
- 320 people
- Sponsor
- West China Hospital
Pancreas Cancer
Pancreaticoduodenectomy in Elderly Pancreatic Ductal Adenocarcinoma Patients
We used the SEER database to analyze the data of patients with PDAC. The database includes patients of 18 registries in the USA from 1973-2013All the malignant cases were followed-up annually to determine vital status.
- Trial name
- NCT03659903
- Testing
- pancreaticoduodenectomy
- Volunteers
- 5,910 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Esophagectomy, Pancreaticoduodenectomy
Preoperative Nutritional Support in Esophagectomy or Pancreaticoduodenectomy
We are proposing to evaluate the benefit of preoperative nutritional support with Impact Advanced Recovery in the most vulnerable group of elective gastrointestinal surgery patients who may experience a complication, esophagus…
- Trial name
- NCT00585624
- Testing
- Impact Advanced Recovery, No supplement
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Wisconsin, Madison
Pancreatic Cancer
Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection
The purpose of this study is to help us learn what the best amount of fluid is that patients should receive during pancreas surgery.
- Trial name
- NCT01058746
- Testing
- restrictive perioperative fluid management, Liberal perioperative fluid management
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pancreaticoduodenectomy, Delayed Gastric Emptying
Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition
Pylorus preserving pancreaticoduodenectomy has been standard procedure for periampullary benign and malignant disease. Delayed gastric emptying is one of most common complications after the procedure.
- Conditions
- Pancreaticoduodenectomy, Delayed Gastric Emptying, Nutrition
- Trial name
- NCT05314244
- Testing
- Pylorus resecting pancreaticoduodenectomy
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreatic Cancer, Periampullary Carcinoma
Evaluation of A New Digestive Reconstruction Procedure Following Pancreatoduodenectomy
The purpose of this study is to evaluate the validity and safety of a modified operative procedure of digestive tract reconstruction following pancreatoduodenectomy which enables the pancreatic juice and bile to bypass at the…
- Trial name
- NCT01931449
- Testing
- Modified method of digestive tract reconstruction, Routine digestive tract reconstruction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Pancreatic Cancer, Pancreas Cancer
Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
The purpose of this study is to prospectively determine the effects of administering proton pump inhibitors (PPIs) following pancreaticoduodenectomy on postoperative outcomes.
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Ampullary Cancer, Pancreas Neuroendocrine Tumor
- Trial name
- NCT05251233
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Washington University School of Medicine
Pancreas Cancer, DVT
Pharmacokinetics of Apixaban in Patients Undergoing Pancreaticoduodenectomy
Study investigators will examine the absorption characteristics of apixaban, a direct-acting oral anticoagulation, in patients who have underwent a particular kind of surgery (pancreaticoduodenectomy) which involves resection of…
- Conditions
- Pancreas Cancer, DVT, Pulmonary Embolism
- Trial name
- PAP-UP (NCT04191928)
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Thomas Jefferson University
Pancreatectomy, Pancreatoduodenectomy
Twenty Years of Pancreatic Surgery in Iceland
A retrospective analysis of patients undergoing pancreatic operations in Landspitali University Hospital, Reykjavik, Iceland, between 2003 and 2022.
- Conditions
- Pancreatectomy, Pancreatoduodenectomy, Distal Pancreatectomy (DP)
- Trial name
- NCT06738914
- Volunteers
- 244 people
- Sponsor
- Linkoeping University