Clinical trials: Whipple Procedure
Postprocedural Delayed Gastric Emptying
A Prospective Randomized Controlled Multicenter Trial of Delayed Gastric Emptying (DGE) After Pancreaticoduodenectomy Evaluating by Gastrointestinal Reconstruction
The purpose of this study is to evaluate the incidence of delayed gastric emptying in patient with pancreaticoduodenectomy between antecolic and retrocolic gastrointestinal reconstruction.
- Trial name
- NCT01460550
- Testing
- Retrocolic gastro- or duodeno- jejunostomy in hte pancreaticoduodenectomy, Antecolic gastro- or duodeno- jejunostomy in the pancreaticoduodenectomy
- Where
- Japan
- Volunteers
- 240 people
- Sponsor
- Kobe University
Pancreaticoduodenal; Fistula
Modified Reconstruction for Pancreatic Head Resection
This observational study aims to prove the safety and efficacy of a modified method of reconstruction after pancreatic head resection utilizing a single Omega shaped intestinal Loop with an additional anastomosis between the…
- Trial name
- NCT03277625
- Testing
- modified omega-shaped single-loop
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- St. Josef Hospital Bochum
Pancreatic Fistula
Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy
The objective of this study is to determine the effect of the sealant patch Hemopatch, compared to current practice without any sealant, on the decrease of the postoperative pancreatic fistula on patients undergoing…
- Trial name
- NCT03419676
- Testing
- Hemopatch
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Hospital Miguel Servet
Major Abdominal Surgery
Glycocalyx Monitoring in Major Abdominal Surgery
The study of the microcirculation and glycocalyx could be an essential element in the monitoring of our patients undergoing major abdominal surgery.
- Trial name
- GLYCOCHIP (NCT06285526)
- Testing
- Cytoreduction surgery with Hyperthermic Intraperitoneal Chemotherapy, Cephalic DuodenoPancreatectomy
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Rouen
Patients Who Undergo Pancreatoduodenectomy
Horizontal Mattress vs. Interrupted Suture in Surgical Techniques of Pancreaticojejunostomy
The aim of this study is to verify that the frequency of pancreatic fistula (ISGPF grade B and C) in horizontal mattress suture are lower than in interrupted suture during pancreaticojejunostomy in pancreatoduodenectomy by…
- Trial name
- NCT01898780
- Testing
- pancreaticojejunostomy with horizontal mattress suture, pancreaticojejunostomy with interrupted suture
- Where
- Japan
- Volunteers
- 190 people
- Sponsor
- Wakayama Medical University
Pancreas Cancer, Surgery-Complications
Relieving the Bile Ducts Prior to Pancreatoduodenectomy
The aim of this study was to assess the risk and complications after preoperative drainage of biliary obstruction in patients who underwent pancreatoduodenectomy.
- Conditions
- Pancreas Cancer, Surgery-Complications, Biliary Fistula
- Trial name
- NCT05434520
- Testing
- Preoperative biliary drainage (ERC og PTC-aided)
- Where
- Denmark
- Volunteers
- 722 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pancreatic Cancer, Pancreatic Fistula
Laparoscopic Pancreaticoduodenectomy
Laparoscopic pancreaticoduodenectomy was first performed by Garner and Pomp in 1994. This is a technically difficult, time consuming and high rate of complication procedure.
- Conditions
- Pancreatic Cancer, Pancreatic Fistula, Periampullary Cancer
- Trial name
- LPD (NCT07009119)
- Testing
- laparoscopic Pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Nonalcoholic Fatty Liver Disease After Pancreaticoduodenectomy
The Impact of Hepatic Steatosis on Survival After Pancreaticoduodenectomy
We will use simple summaries, educational handouts, and discussions with doctors and nurses to explain this study. The study looks at patients with early-stage pancreatic cancer who undergo pancreaticoduodenectomy (Whipple…
- Trial name
- NCT07182136
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- Wei-Hsun Lu
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Pancreatic Fistula
External Pancreatic Duct Stent After Pancreaticoduodenectomy
Pancreatoduodenectomy (PD) is performed in many high volume centers with a very low mortality. Reduced mortality rate is largely the result of careful patient selection, improved intraoperative management and a better…
- Trial name
- NCT01068886
- Testing
- External pancreatic stent
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Hepatocellular Carcinomas, Cholecystectomy, Laparoscopic
A Multicenter Prospective Observational Study of Computer-aided Risk Perception and Prognosis Prediction in the Whole Process of Laparoscopic Hepatobiliary and Pancreatic Surgery
Artificial intelligence technology is used to realize high-quality 3D scene reconstruction, whole process segmentation, scene activity understanding for common surgery guidance in hepatobiliary surgery, as well as intelligent…
- Conditions
- Hepatocellular Carcinomas, Cholecystectomy, Laparoscopic, Hepatectomy, Pancreatoduodenectomy
- Trial name
- NCT06647264
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Pancreatitis, Pancreatic Fistula
Post-Operative Acute Pancreatitis After Pancreaticoduodenectomy
The occurrence of post-pancreatectomy acute pancreatitis (PPAP) can critically impact outcomes after pancreaticoduodenectomy. Although diagnosing a PPAP can be challenging, its identification appears crucial as it can trigger…
- Conditions
- Acute Pancreatitis, Pancreatic Fistula, Postoperative Complications
- Trial name
- NCT04917172
- Testing
- postoperative acute pancreatitis evaluation
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Lobectomy, Hepatectomy
Microsleep 1, Micro-sleep During Maintenance Wakefulness Tests
During general anesthesia, intraoperative hypotension (IOH) is associated with increased morbidity and mortality. Mean arterial pressure (MAP) < 65mmHg is the most common definition of hypotension.
- Conditions
- Lobectomy, Hepatectomy, Pancreaticoduodenectomy
- Trial name
- NCT04559269
- Testing
- No intervention
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Hospices Civils de Lyon
Pancreatoduodenectomy, Whipple Procedure
Antiseptic-Coated Sutures and Pancreatic Fistula Risk After Pancreatoduodenectomy
The purpose of this study is to determine if the use of antiseptic-coated sutures is better than the use of the standard sutures in preventing postoperative fistulas within 90 days after pancreatoduodenectomy.
- Trial name
- Triclosan (NCT07318493)
- Testing
- Standard (non-antiseptic coated) suture will be used., Triclosan/antiseptic -coated suture
- Where
- 3 sites in United States
- Volunteers
- 436 people
- Sponsor
- The Cleveland Clinic
Pancreas Cancer
Early Recovery Outcomes After Standardized Fast-track Whipples Procedure
Today the Whipple procedure is the preferred operation for malignancy in the pancreas. In abdominal surgery this procedure is known for its high surgical stress-response in the patient, which has been attempted to be resolved…
- Trial name
- NCT03566056
- Testing
- Complications to Whipples procedure
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Eske Kvanner Aasvang
Pancreatic Cancer
Effectiveness of the Transversus Abdominis Plane Block Associated With Opioid Spinal Anesthesia on Analgesia After Cephalic Duodenopancreatectomy
Duodenopancreatectomy is a major, risky surgery that causes significant post-operative pain. Optimizing perioperative analgesia remains a challenge, and requires multimodal management, notably involving locoregional analgesic…
- Trial name
- DPC-RATAP (NCT06499792)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Strasbourg, France
Pancreas Disease
Postoperative Pancreatitis and Its Correlation With Clinically Relevant Pancreatic Fistula in Pancreaticoduodenectomy
AIM To determine association between postoperative pancreatitis and pancreatic fistula OBJECTIVES 1. To determine incidence of Clinically relevant pancreatic fistula (grade B/C) after pancreaticoduodenectomy 2.
- Trial name
- NCT04514198
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Asian Institute of Gastroenterology, India
Major Abdominal Surgery, Colorectal Surgery
Automated Versus Manual Fluid Management for High Risk Abdominal Surgical Patient. A Prospective, Randomized Trial
Dynamic parameters like pulse pressure variation have been shown to be accurate predictors of fluid responsiveness. Hemodynamic optimization based on fluid management and stroke volume optimization have been shown to improve…
- Conditions
- Major Abdominal Surgery, Colorectal Surgery, Hepatectomy, Pancreatectomy
- Trial name
- CL vs CP (NCT01950845)
- Testing
- Closed loop automated System (LIR®: learning intravenous resuscitator), manual current practice by anesthesiologist team
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hospices Civils de Lyon
Pancreatoduodenectomy
Pancreatoduodenectomy With or Without Ligamentum Teres Wrap Around Gastroduodenal Artery Stump for Prevention of Pancreatic Hemorrhage
To investigate, whether a prophylactic wrapping of the gastroduodenal artery stump with the ligamentum teres or falciform hepatic (embryological structures, covered with peritoneum that do not have relevant meaning for adults)…
- Trial name
- NCT02588066
- Testing
- Ligamentum teres/falciform-plasty
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Technische Universität Dresden
Pancreaticoduodenectomy
Comparison of Hemodynamic Effects of Two Colloid Therapies in Post-operative Patients Undergoing Pancreaticoduodenectomy
From postoperative patients having undergone pancreaticoduodenectomy; 1. To compare the hemodynamic parameters from the patient administrated 5% HA and 6% Voluven 2.
- Trial name
- NCT01758172
- Testing
- 6% hydroxyethyl starch 130/0.4, Albumin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center