Clinical trials: Whipple Procedure
Pancreatic Fistula
Buttressed Pancreatico-Gastrostomy for Soft Pancreas With Small Diameter Pancreatic Duct in Whipple Procedure
Post-operative pancreatic fistula after Pancreaticoduodenectomy procedure, is still a major complication that might be affected by pancreatic stump reconstruction technique. More than 60 techniques were published in literature.
- Trial name
- NCT05682768
- Testing
- Duct to Mucosa Pancreatico-Gastrostomy with trans-pancreatic transverse mattress U- Shaped sutures
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- South Valley University
Pancreaticoduodenectomy
Early POstoperative BIomarkers in PancreatoDuodenectomy: a Spanish Nationwide Study
AIMS: To recruit a large nationwide Spanish series in order to register PF rate and other common morbidity after PD, and to perform external validation of the aforementioned score, as well as to analyze other postoperative blood…
- Trial name
- EPOBIPD (NCT04342923)
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Pancreatectomy, Complication of Surgical Procedure
Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty
To assess the efficacy of complete covering using retromesenteric omentoplasty vs. partial covering or no covering of peripancreatic arteries in decreasing incidence of grade B+C post-pancreatectomy hemorrhage (PPH), i.e.
- Trial name
- PACOMARCO (NCT05992857)
- Testing
- Pancreaticoduodenectomy without retromesenteric omental flap, Pancreaticoduodenectomy with retromesenteric omental flap
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Periampullary Carcinoma Resectable
Pancreatoduodenectomy With Mesopancreas Dissection.A Prospective Study Comparing Artery-first Approach Versus Standard Approach
The definitions for R0 and R1 margin status after resection for pancreatic cancer are controversial.Various studies showed the rate of noncurative resections of 15- 35 % but with modified pathological examination (R1/R2) revealed…
- Trial name
- NCT03224832
- Testing
- Artery-first Approach, Standard Approach
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pancreatic Ductal Adenocarcinoma
Lymphadenectomy for Pancreatic Head Cancer: Standard or Extended?
The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer
- Trial name
- NCT02787187
- Testing
- Pancreaticoduodenectomy with Standard lymphadenectomy, Pancreaticoduodenectomy with Extended lymphadenectomy
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Ruijin Hospital
Periampullary Carcinoma
Comparison of Blood Loss in Laparoscopic vs Open Pancreaticoduodenectomy in Patients With Periampullary Carcinoma
the study is designed to compare the blood loss between laparoscopic vs open pancreaticoduodenectomy in a randomized clinical trial
- Trial name
- NCT03722732
- Testing
- pancreaticoduodenectomy
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Govind Ballabh Pant Hospital
Post Operative Pancreatic Fistula, Pancreatic Resection
Efficacy of Amniotic Membrane Over Pancreatic Anastomosis After Pancreaticoduodenenctomy to Preventing Pancreatic Fistula
Post-operative pancreatic fistula (POPF) after pancreatic resection is a potentially life-threatening complication occuring in up to 27% of patients undergoing a pancreatic resection.
- Conditions
- Post Operative Pancreatic Fistula, Pancreatic Resection, Biological Dressing
- Trial name
- POPF (NCT03891225)
- Testing
- Amniotic Membrane implantation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Pancreatic Cancer, Ampulla of Vater Adenocarcinoma
Nutritional Intervention Implication in Enhanced Recovery After Surgery for Whipple Procedure
The objective of this research is to assess the impact of personalized nutritional intervention on postoperative complications and length of stay in Whipple's patients via assessing the parameters related to body composition…
- Conditions
- Pancreatic Cancer, Ampulla of Vater Adenocarcinoma, Billiary Track Cancer
- Trial name
- {ERAS} (NCT07560540)
- Testing
- Nutrition Intervention
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Periampullary Cancer
Clinical Impact of Altitude Level on Surgical Outcomes of Pancreaticoduodenectomy
Very few papers examine the effect of living at high altitudes on surgical results of major operations. This research is designed to determine the surgical outcomes of PD for periampullary tumour in high altitudes and normal…
- Trial name
- PD (NCT04401722)
- Testing
- PANCREATICODUDENECTOMY
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Pancreas Head Cancer, Pancreas Adenocarcinoma
Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)
The PANENCA trial aims to reduce postoperative complications in patients undergoing pancreatoduodenectomy (also known as a Whipple procedure), a complex surgical operation performed to remove tumors located in or near the head of…
- Conditions
- Pancreas Head Cancer, Pancreas Adenocarcinoma, IPMN, Pancreatic, Cholangio Carcinoma
- Trial name
- PANENCA (NCT07262957)
- Testing
- HOP bundle
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Total Pancreatectomy, Pancreaticoduodenectomy
Hepatic Histology and Metabolism Following Total Pancreatectomy and Pancreaticoduodenectomy
The objective of the study is to investigate the development of NAFLD following total pancreatectomy and pancreaticoduodenectomy and to explore the histological and metabolic changes following the procedures.
- Conditions
- Total Pancreatectomy, Pancreaticoduodenectomy, Pancreatic Diabetes, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT03864744
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- Steno Diabetes Center Copenhagen
Periampullary Carcinoma, Pancreatic Cancer
Reoperation After Pancreaticoduodenectomy
The aim of this study is to outline the incidence of early and late reoperation after PD, examine the risk factors for early surgical intervention and its impact on the surgical outcome, hospital stay, diseases recurrence and…
- Trial name
- NCT04387903
- Testing
- Surgical re-interventionafter pancreaticoduodenectomy
- Volunteers
- 1,000 people
- Sponsor
- Mansoura University
Laparoscopic Pancreaticoduodenectomy
Analysis of Intraoperative Bleeding Characteristics in Laparoscopic Pancreaticoduodenectomy
In this study, we analyze the common bleeding characteristics in laparoscopic pancreaticoduodenectomy by reviewing and annotating bleeding information from previous surgical videos as well as surgical operation OSATS technique…
- Trial name
- NCT06128603
- Testing
- laparoscopic pancreaticoduodenectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinrui Zhu，MD
Pancreatic Cancer Resectable
Conventional Partial Pancreatoduodenectomy Versus an Extended Pancreatoduodenectomy for Pancreatic Head Cancers
The goal of this clinical trial is to learn if traditional pancreaticoduodenectomy (PD) combined with TRIANGLE (extended PD surgery) can increase disease-free survival (DFS) in patients with pancreatic head cancers compared to…
- Trial name
- NCT06703905
- Testing
- Expanded pancreaticoduodenectomy surgery, Pancreaticoduodenectomy
- Volunteers
- 270 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Pancreaticoduodenectomy
Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy
Postoperative pancreatic fistula (POPF) especially clinically relevant POPF (CR-POPF; Grades B and C) is one of the critical and challenging post pancreaticoduodenectomy complications.
- Trial name
- NCT07854353
- Testing
- pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cancer of Pancreas
Pancreatico Enteric Anastomosis Post Pancreaticoduodenectomy
The aim of this study is to make a step for evaluation and presentation of a safe technique for pancreatico-jejunostomy that help in minimizing post-operative morbidity and mortality in pancreatic cancer patient by comparing…
- Trial name
- PEAPP (NCT05163977)
- Testing
- Blumgart Anastomosis, Cattell Warren Anastomosis
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pancreatic Cancer, Pancreas Cancer
Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?
The purpose of this study is to figure out which commonly used antibiotic, cefoxitin or piperacillin-tazobactam, is better at decreasing the rate of surgical site infections after pancreatoduodenectomy.
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Pancreatic Diseases
- Trial name
- NCT03269994
- Testing
- Cefoxitin, Piperacillin-tazobactam
- Where
- 32 sites in United States, Canada
- Volunteers
- 967 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Different Pancreaticojejunostomy After Pancreaticoduodenectomy
The aim of this study was to reduce the incidence of postoperative pancreatic fistula after pancreaticoduodenectomy by using different pancreaticojejunostomy methods according to the position of the pancreatic duct.
- Trial name
- NCT05475275
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 924 people
- Sponsor
- Junjie Xiong
Pancreatoduodenectomy, Periampullary Carcinoma
Application of "Heidelberg Triangle" Dissection in Pancreatoduodenectomy and Distal Pancreatectomy
Aim of the study : To evaluate the effect and safety of "Heidelberg Triangle" dissection (TRIANGLE operation) combined with Pancreatoduodenectomy or Distal Pancreatectomy on the prognosis of pancreatic cancer and periampullary…
- Conditions
- Pancreatoduodenectomy, Periampullary Carcinoma, Pancreatic Cancer
- Trial name
- NCT05703581
- Testing
- TRIANGLE operation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Pancreas Cancer, Periampullary Cancer
Reconstruction Following Pancreaticoduodenectomy: A Randomized Clinical Trial of Pancreaticojejunostomy vs Pancreaticogastomy
Pancreaticoduodenectomy (PD or Whipple procedure) involves the removal of the head of the pancreas and is the primary modality for treatment of peri-ampullary cancers (arising from the common bile duct, Ampulla of Vater…
- Trial name
- NCT00841607
- Testing
- pancreaticojejunostomy vs pancreaticogastrostomy
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Tom Baker Cancer Centre