Clinical trials: Whipple Procedure
Pancreatic Fistula
Clinically Relevant Pancreatic Fistula After Pancreaticoduodenectomy
Patients who are diagnosed with periampullary cancer will be performed pancreaticoduodenectomy with 3 types of pancreatic-jejunal anastomosis reconstructions.
- Trial name
- NCT05017207
- Testing
- Pancreaticoduodenectomy
- Where
- Vietnam
- Volunteers
- 183 people
- Sponsor
- Vo Truong Quoc
Pancreatic Diseases, Pancreas Cancer
Improvement of Care of Patients Undergoing Pancreaticoduodenectomy
The study is a randomised controlled trial comparing the effectivity and impact of epidural analgesia and wound catheter analgesia in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT04668781
- Testing
- Analgesia via epidural catheter, Analgesia via wound catheter
- Where
- Finland
- Volunteers
- 92 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Fistula, Complications of Surgical and Medical Care: General Terms
External Drainage Versus Internal Drainage of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD)
Postoperative pancreatic fistula (POPF) and other surgical complications are common after pancreatoduodenectomy (PD) and POPF is a major complication.
- Trial name
- EDIDPD (NCT01634971)
- Testing
- Internal Drainage of Pancreatic Duct after pancreatomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Cancer, Bile Duct Cancer
Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticoduodenectomy
This study aims to evaluate whether the incidence of delayed gastric emptying (DGE) can be reduced by proximal Roux-en-y gastrojejunal anastomosis in comparison with the standard gastrojejunal anastomosis in pylorus-resecting…
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Duodenal Cancer
- Trial name
- NCT02954302
- Testing
- PrPD with proximal Roux-en-y gastrojejunal anastomosis, conventional PrPD
- Where
- China
- Volunteers
- 140 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Pancreatic Cancer
Resection of the Nerve Plexus on the Right Half of Celiac and SMA Associated With Extended Pancreatoduodenectomy in the Surgical Treatment for Adenocarcinoma of the Head of Pancreas
This study is performed to confirm whether resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy could improve survival and relieve pain of pancreatic cancer patients.
- Trial name
- NCT02514928
- Testing
- resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy, standard pancreatoduodenectomy
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Fudan University
Pancreatic Cancer
Comparison of Transmesocolic Versus Retromesenteric Reconstruction in Cephalic Duodenopancreatectomy (FAST Trial)
Objective: To compare the incidence of delayed gastric emptying (ISGPS 2007 criteria) between patients undergoing retromesenteric versus transmesocolic reconstruction after pancreaticoduodenectomy.
- Trial name
- FAST (NCT07368218)
- Testing
- Retromesenteric reconstruction, Transmesocolic reconstruction
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Hospital Universitari de Bellvitge
Pancreatic Head Cancer, Pancreatic Ductal Adenocarcinoma
Prognostic Outcomes of Total Mesopancreas Excision for Pancreatic Head Cancer
Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis due to high recurrence rates after standard pancreaticoduodenectomy (PD).
- Trial name
- TMpE (NCT07232810)
- Testing
- Total Mesopancreas Excision (TMpE)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Surgery, Infection
Antibiotic Irrigation for Pancreatoduodenectomy
The purpose of this study is to determine if the routine use of antibiotic irrigation during pancreas surgery (Whipple procedure) will decrease superficial and organ space infections.
- Trial name
- NCT02186457
- Testing
- Polymyxin B in Normal Saline
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Indiana University
Pancreatic Ductal Adenocarcinoma
Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy for Malignant Disease
The aim of this study is to assess whether prehabilitation supervised by an appropriate multimodality team improves indices of sarcopenia in patients scheduled to undergo pancreatoduodenectomy.
- Trial name
- SIPUP (NCT03770117)
- Testing
- Prehabilitation, Standard Procedure
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- Manchester University NHS Foundation Trust
Pancreatic Fistula
Closed Suction Drainage and Natural Drainage of the Pancreatic Duct in Pancreaticojejunostomy
Pancreaticojejunal anastomosis leakage is a major complication after pancreatoduodenectomy and various technical methods have been examined to improve the situation.However, none of methods have been successful at improving…
- Trial name
- NCT00679952
- Testing
- closed suction drainage of pancreatic duct, natural drainage of pancreatic duct
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
Postprocedural Gastric Stasis
Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following Pancreaticoduodenectomy
Patients undergoing whipples pancreaticoduodenectomy tend to develop delayed gastric emptying. The study compares two types of anastamosis of stomach to jejunum (supracolic and infracolic) and compares whether it influences the…
- Trial name
- NCT01191138
- Testing
- Infracolic gastrojejunal anastamosis, Supracolic gastrojejunal anastamosis
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreas Adenocarcinoma
A Study of Extended Total Mesopancreas Excision(eTME) for Pancreatic Head Adenocarcinoma.
The study of extended total mesopancreas excision(eTME) for pancreatic head adenocarcinoma is a retrospective multicenter cohort, collecting medical records and follow-up data of patients who underwent radical resection with…
- Trial name
- NCT04147403
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Pancreas Cancer
Pancreaticoduodenectomy in Elderly Pancreatic Ductal Adenocarcinoma Patients
We used the SEER database to analyze the data of patients with PDAC. The database includes patients of 18 registries in the USA from 1973-2013All the malignant cases were followed-up annually to determine vital status.
- Trial name
- NCT03659903
- Testing
- pancreaticoduodenectomy
- Volunteers
- 5,910 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Intraoperative Care, Fluid Responsiveness
Short Time Low PEEP Challenge and Mini Fluid Challenge
Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy.
- Trial name
- NCT05419570
- Testing
- Fluid Loading
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul Saglik Bilimleri University
Whipple Procedures, Pancreatic Cancer
Energy Expenditure and Nutrition After Pancreatic Surgery
This prospective observational cohort study examines the energy requirements and nutritional care of patients undergoing total or partial pancreatectomy for pancreatic tumors.
- Conditions
- Whipple Procedures, Pancreatic Cancer, Pancreaticoduodenectomy, Pancreatic Neoplasms
- Trial name
- NUTRI-PD (NCT07703813)
- Testing
- Pancreatectomy, Indirect calorimetry
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Evangelismos Hospital
Pancreaticoduodenectomy
Investigation of Pancreaticoduodenectomy
The investigators intend to conduct a multicentre, big-sample, retrospective study to analysis the surgery results of pancreaticoduodenectomy and compare the different suture technique.
- Trial name
- NCT03791450
- Where
- China
- Volunteers
- 10,085 people
- Sponsor
- Tongji Hospital
Whipple Procedure
Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center
The study was conducted in tertiary care hospital of Lahore. Patient undergoing Whipple procedure were studied by compiling demographic details of the patients, common presenting symptoms, various indications for Whipple's…
- Trial name
- NCT03820583
- Testing
- Whipple Procedure
- Where
- Pakistan
- Volunteers
- 57 people
- Sponsor
- Services Hospital, Lahore
Pancreatic Cancer
Biliary Drainage Preceding Possible Pancreaticoduodenectomy. Are Self-expandable Metallic Stents (SEMS) Superior to Plastic Stents?
This study looks in to the rate of biliary stent dysfunction for plastic and metallic stents in patients who need biliary drainage due to a tumor in pancreas before possible pancreaticoduodenectomy.
- Trial name
- NCT03350763
- Testing
- Tannenbaum 10 Fr biliary stent, Self-expandable metallic biliary stent
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Omental Patch, Laparoscopic Pancreaticoduodenectomy
A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Pancreaticoduodenecotmy(PD) is considered as the standard procedure for peri-amplullary or pancreatic head tumors. Laparoscopic pancreaticoduodenctomy(LPD) has been reported with minimal invasive advantages, such as small…
- Conditions
- Omental Patch, Laparoscopic Pancreaticoduodenectomy, Pancreatic Fistula
- Trial name
- NCT04704882
- Testing
- omental patchwork
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhejiang Provincial People's Hospital