Clinical trials: White Blood Cell Count
Systemic Inflammatory Response Syndrome, Sepsis
Comparison the Value of Several Biomarkers of Sepsis
The purpose of this study is to describe the value of serum sTREM (soluble triggering receptor expressed on myeloid cells)-1, sCD163, procalcitonin (PCT), C-reactive protein (CRP) concentrations, white blood cell (WBC) count and…
- Trial name
- NCT01388725
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Chinese PLA General Hospital
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Leukopenia, Leukocytosis
A Comparator Study of a Tasso Device Blood Sample to Traditional Venous Blood Sample for CBC
This study will evaluate the feasibility of using capillary blood samples collected with the Tasso device for analysis of CBC in diseased patients with leukemia, lymphoma, and/or other blood cell disorders.
- Conditions
- Leukopenia, Leukocytosis, Neutropenia
- Trial name
- NCT06360952
- Testing
- Tasso+ CBC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tasso Inc.
Acute Biphenotypic Leukemia, Acute Myeloid Leukemia
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia
This phase II trial studies how well cladribine, idarubicin, cytarabine, and venetoclax work in patients with acute myeloid leukemia, high-risk myelodysplastic syndrome, or blastic phase chronic myeloid leukemia.
- Conditions
- Acute Biphenotypic Leukemia, Acute Myeloid Leukemia, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blasts 10 Percent or More of Bone Marrow Nucleated Cells
- Trial name
- NCT02115295
- Testing
- Cladribine, Cytarabine, Gilteritinib
- Where
- United States
- Volunteers
- 508 people
- Sponsor
- M.D. Anderson Cancer Center
Non Small Cell Lung Cancer
A Study of Efbemalenograstim Alfa Injection for Stage IIIB or IV NSCLC Recieving Moderate-risk Febrile Neutropenia (FN) Chemotherapy Regimen With Risk Factors
The aim of this study was to observe the efficacy and safety of Efbemalenograstim Alfa in the prevention of absolute neutrophil count (ANC) reduction after chemotherapy in NSCLC patients at risk of platinum-containing…
- Trial name
- NCT06143735
- Testing
- Efgbemalenograstim alfa
- Where
- 10 sites in China
- Volunteers
- 99 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
All Conditions Causing Sepsis, Pneumonia - Bacterial
Comparison Between the Progostic Value of the Procalcitonin and the Platelet/Total Leukocytic Count Ratio in Sepsis
What is already known on this subject? AND What does this study add? Sepsis is a complicated condition caused by a malfunction of the host's immune response to infection, which results in an uncontrollable inflammatory response…
- Conditions
- All Conditions Causing Sepsis, Pneumonia - Bacterial, Urinary Tract Infection Bacterial
- Trial name
- NCT06991686
- Testing
- Blood samples, blood sample
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Kidney Neoplasms
Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer
Background: Some patients with advanced kidney cancer have immune cells that can recognize and kill their cancer, but the cells are not active enough or numerous enough to accomplish this on their own.
- Trial name
- NCT00091611
- Testing
- IL-2 (interleukin-2), OKT3, Cyclophosphamide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Cancer Institute (NCI)
Oral Squamous Cell Carcinoma (OSCC), Premalignant Lesion
Comparison of TLC (Total Leucocyte Count), Neutrophils and Monocytes in Oral Squamous Cell Carcinoma and Pre-malignant Disorders
Oral squamous cell carcinoma is one of the significant public health concerns and the most prevalent malignancies affecting the head and neck region globally.
- Trial name
- NCT07899255
- Testing
- CBC will be required to assess the level of TLC (Total Leucocyte Count), Neutrophils and Monocytes in patient of oral squamous cell carcinoma and oral pre malignant conditions, using different stains
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Dow University of Health Sciences
Blasts Under 5 Percent of Peripheral Blood White Cells, Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment Level
Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation
This phase II trial studies how well enasidenib works in treating in patients with acute myeloid leukemia with an IDH2 gene mutation that has come back or has not responded to treatment.
- Conditions
- Blasts Under 5 Percent of Peripheral Blood White Cells, Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment Level, IDH2 Gene Mutation, Recurrent Acute Myeloid Leukemia
- Trial name
- NCT03881735
- Testing
- Enasidenib, Hematopoietic Cell Transplantation
- Where
- 2 sites in United States
- Sponsor
- Roswell Park Cancer Institute
SARS-CoV-2 Infection Covid19
Differential Leucocyte Count and Covid-19 Diagnosis
To date, the diagnosis of SARS-CoV-2 infection is made by identifying the viral RNA in samples collected through a nasopharyngeal swab or other respiratory samples but this technique, has several limitations for its application…
- Trial name
- NCT04643860
- Testing
- Differential Leucocyte Count (CLDC) device and algorithm
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Ventricular Fibrillation
Influence of Mild Therapeutic Hypothermia on Leukocyte Count
Mild therapeutic hypothermia is indicated in patients surviving out-of-hospital cardiac arrest due to ventricular fibrillation. Potential immunologic responses are unknown.
- Trial name
- INCA (NCT00520520)
- Where
- Germany
- Sponsor
- Charite University, Berlin, Germany
BCR-JAK2 Fusion Protein Expression, Blasts 20 Percent or Less of Peripheral Blood White Cells
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders
This phase II trial studies how well ruxolitinib works in treating patients with hypereosinophilic syndrome or primary eosinophilic disorders.
- Conditions
- BCR-JAK2 Fusion Protein Expression, Blasts 20 Percent or Less of Peripheral Blood White Cells, Blasts More Than 5 Percent of Bone Marrow Nucleated Cells, Blasts More Than 5 Percent of Peripheral Blood White Cells
- Trial name
- NCT03801434
- Testing
- Ruxolitinib
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Breast Cancer, Lung Cancer
Prognostic Value of Divpenia and CD4 Count in Relapsed Breast or Lung Cancer Patients
The T and B cells repertoire diversity represent one of the immune defence level which controls the integrity of the organism and determines its ability to recognize and control infectious attacks and development of tumours.
- Trial name
- LYMPHOS1 (NCT01306188)
- Testing
- Breast cancer cohort, Lung cancer cohort
- Where
- 4 sites in France
- Volunteers
- 179 people
- Sponsor
- Centre Leon Berard
Lymphopenia
Lymphocyte Count as a Sign of Immunoparalysis and Its Correlation With Nutritional Status in Septic Pediatric Patients
Participants were classified as normal or malnourished according to anthropometric measures. Serum albumin and zinc were recovered on the 1st and 7th days of hospitalization.
- Trial name
- NCT02698683
- Testing
- lymphocyte count
- Volunteers
- 14 people
- Sponsor
- University of Sao Paulo
Neutropenic Fever
Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against Infection
This is a comparative study for adult participants with cancer who are suspected to have neutropenic fever (or fever with low neutrophil count) in emergency department.
- Trial name
- FRANCiS-NF (NCT05393505)
- Testing
- Meropenem Injection, Levofloxacin, Amoxicillin Clavulanate
- Where
- Hong Kong
- Volunteers
- 344 people
- Sponsor
- The University of Hong Kong
Breast, Breast Cancer
Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer
The overall purpose of this study is to investigate whether younger subjects report pain with pegfilgrastim (or biosimilar substitution) more often and/or at higher levels (greater intensity) than older subjects.This study will…
- Trial name
- NCT04174742
- Testing
- pegfilgrastim
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Wake Forest University Health Sciences
Acute Myeloid Leukemia With Multilineage Dysplasia, Blasts 20-30 Percent of Bone Marrow Nucleated Cells
Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome
This phase I/II trial studies the side effects of glutaminase inhibitor CB-839 in combination with azacitidine in treating patients with myelodysplastic syndrome that has spread to other places in the body.
- Conditions
- Acute Myeloid Leukemia With Multilineage Dysplasia, Blasts 20-30 Percent of Bone Marrow Nucleated Cells, Blasts 20-30 Percent of Peripheral Blood White Cells, Chronic Myelomonocytic Leukemia
- Trial name
- NCT03047993
- Testing
- Azacitidine, Glutaminase Inhibitor CB-839
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Anastomotic Leak
Role of Procalcitonin, C-Reactive Protein, and WBC Count in Prediction of Colorectal Anastomotic Leak
The interest in identifying a biological marker for the early detection of AL is growing. Such a marker could play a vital role in modern fast-track multimodal protocols, allowing safe and early discharge of patients after…
- Trial name
- NCT05159024
- Testing
- CRP, PCT, and WBCs trajectories
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Suez Canal University
Given Indication for Open Resection of Colorectal Cancer
Diagnostic Value of C-reactive Protein and White Blood Cell Counts for Early Detection of Inflammatory Complications After Open Resection of Colorectal Cancer
Although widely used, there is a lack of evidence concerning diagnostic value of C-reactive protein (CRP) and white blood cell counts (WBC) in the postoperative course.
- Trial name
- NCT01221324
- Volunteers
- 1,200 people
- Sponsor
- Cantonal Hospital of St. Gallen
White Blood Cells Engulfing Red Blood Cells
Usefulness of White Blood Cell Count (WBCC) During Infection in Geriatric Patient
In the general population, increased WBCC and neutrophil count are widely used as markers for infection during inflammatory states 1. However, 32% of geriatric patients with an infection do not develop an increase in WBCC 2.
- Trial name
- NCT03943277
- Testing
- No intervention, observational study
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- Universitair Ziekenhuis Brussel