Clinical trials: Whitening
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin
Efficacy Validation of Deep Microspicule Cream for Anti-aging and Whitening on Mature Skin
This study is a single-center, prospective, split-face self-controlled pilot trial designed to evaluate the anti-aging and whitening efficacy of the "Deep Microspicule Cream" (containing patented crystal microspicules…
- Trial name
- NCT07774260
- Testing
- Deep Microspicule Cream
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Tooth Sensitivity, Teeth Whitening
Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide.
Despite the wide range of desensitizing agents available on the market, there is still no gold standard treatment that is fully effective in managing sensitivity by dental bleaching.
- Trial name
- NCT07478640
- Testing
- Bioadhesive film of Acmella Oleracea (jambu), Gel containing 5% potassium nitrate and 2% sodium fluoride., Spilanthol-free bioadhesive bioplastic film
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Whitening
Efficacy of a Toothpaste Containing Hydrogen Peroxide as Compared to a Regular Fluoride Toothpaste Without Hydrogen Peroxide in the Immediate Removal of Tooth Stains After a Single Brushing.
The aim of this study is to evaluate and compare the immediate efficacy of a hydrogen peroxide-containing toothpaste versus a regular fluoride toothpaste without hydrogen peroxide in removing extrinsic tooth stains following a…
- Trial name
- NCT07276672
- Testing
- Optic White Adv Sparkling White (2%HP) Toothpaste, Colgate Great Regular Flavor Toothpaste
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Whitening
Clinical Study to Evaluate the Tooth Whitening Efficacy
Optic White 5%HP ActivShine TP vs Crest3D White TP (head-to-head whitening clinical) The objective of this study is to evaluate the tooth whitening efficacy of a Colgate toothpaste with 5% Hydrogen Peroxide and Fluoride compared…
- Trial name
- NCT06957249
- Testing
- Optic White 5%HP ActivShine Toothpaste, Crest3DWhite Advanced Radiant Mint Toothpaste
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Whitening
Evaluate the Efficacy and the Tolerance of the Medical Device V063B-DP3003 on Dentin Hypersensitivity During Teeth Whitening
A dental gel intended to relieve pain related to dentin hyper sensitivity is commercialized in several countries worlwide since May 2017. Its efficacy and tolerance has already been proven in dentin hyper sensitivity.
- Trial name
- NCT05804994
- Testing
- Elgydium Clinic Sensileave Gel (V063B - DP3003)
- Where
- Poland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Teeth Whitening
Tooth Whitening Evaluation With Cytotoxic and Genotoxic Effect of Commercial Whitening Toothpastes on Oral Mucosal Cells
Bleaching discolored vital teeth is one of the most popular aesthetic treatment in dentistry in the last decade. Teeth whitening can be performed by professionals/dentists in the dental office ("in-office") and by the patients…
- Trial name
- NCT04460755
- Testing
- Control group, Whitening toothpaste 1, Whitening toothpaste 2
- Where
- Croatia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Tooth Whitening
Investigation of the Instant Tooth Whitening Effect of a Silica Toothpaste Containing Blue Covarine
The study investigates the effect of toothbrushing with a toothpaste containing blue covarine compared to a control toothpaste without blue covarine on tooth color.
- Trial name
- NCT03760367
- Testing
- Blue covarine toothpaste, Control toothpaste
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Glutathione, Skin Whitening
Oral Glutathione As A Skin Whitening Agent
The objective of the study was to evaluate the efficacy and safety of oral glutathione for 12 weeks, used as a skin-whitening agent.
- Trial name
- NCT04105504
- Testing
- Glutathione
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr Irma Bernadette S Sitohang
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Skin Whitening
Role of Oral Glutathione in Skin Whitening
Oral and intravenous glutathione have been used widely to whiten the skin. The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.
- Trial name
- NCT01016080
- Testing
- glutathione
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chulalongkorn University
Tooth Whitening
Clinical Study to Evaluate of The Whitening Efficacy and Safety of REMEWHITE
The purpose of this study is to determine the effect of REMEWHITE on tooth whitening.
- Trial name
- REMEWHITE (NCT00978861)
- Testing
- Hydrogen Peroxide
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- JDC Tech