Clinical trials: Willpower
Cirrhosis, Hepatorenal Syndrome
Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome
From 1999, several studies have showed that the use of vasoconstrictors in association with albumin are effective in the treatment of hepatorenal syndrome (HRS).
- Trial name
- NCT00742339
- Testing
- Terlipressin plus albumin, Midodrine plus octreotide plus human albumin
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Padova
Anodal Stimulation tDCS, Major Depression
Effects of tDCS on Cognitive Control and Emotion Regulation in Depressed Patients
Deficient cognitive control (CC) and the use of dysfunctional emotion regulation strategies (ERS) are both central characteristics of major depression.
- Conditions
- Anodal Stimulation tDCS, Major Depression, Cognitive Control, Emotion Regulation
- Trial name
- NCT03039387
- Testing
- anodal transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Loneliness
The Effects of Transcranial Direct Current Stimulation (tDCS) in Older Lonely Individuals
This randomized clinical trial aims to test the effects of 10 sessions of transcranial direct current stimulation (tDCS) on social and emotional functions in lonely older adults.
- Trial name
- NCT05937022
- Testing
- Experimental Transcranial Direct Current Stimulation (tDCS)
- Where
- Hong Kong
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Malaria, Malaria Vivax
This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria
The goal of this Phase 2b study is to examine the safety and efficacy of the combination of SJ733, an investigational agent, and tafenoquine for the radical cure of uncomplicated P.
- Conditions
- Malaria, Malaria Vivax, Radical Cure
- Trial name
- SJ733-2002 (NCT07430592)
- Testing
- CQ/TQ, SJ733 (3-day)/TQ, SJ733 (2-day ) /TQ
- Where
- Peru
- Volunteers
- 104 people
- Sponsor
- R. Kiplin Guy
Behavior, Addictive, Cigarette Smoking
Practicing Self-Control Lowers the Risk of Smoking Lapse
The proposed study will investigate the role of self-control in smoking cessation and whether interventions that improve self-control can help reduce the risk of lapsing among smokers who wish to quit.
- Trial name
- NCT00349687
- Testing
- self-control practice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University at Albany
Patient Satisfaction
This Study Will Assess Whether the Treatment Provided by Dentist is Successful in Meeting the Expectations of Patient by Asking Questions Related to Aesthetics, Chewing Ability, Comfort and Phonetics Before and After Providing Treatment and the Patient Will Tell Through Visual Analog Scale
This study aims to assess patient satisfaction after receiving porcelain-fused-to-metal fixed dental prostheses. Patients will be asked about their expectations before treatment and their satisfaction afterward.
- Trial name
- NCT07100678
- Testing
- Porcelain-Fused-to-Metal Fixed Dental Prosthesis
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Mental Health
Life Skills Boot Camp Study (LEVELUP2)
In the present study, the investigators aim to examine a) the acceptability and feasibility of the "Life Skills Boot Camp", a series of soft skills trainings for students in higher education.
- Trial name
- LEVELUP2 (NCT05713747)
- Testing
- Life Skills Boot Camp
- Where
- 4 sites in Cyprus, Greece and 2 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Liver Cancer, Pancreas Cancer
A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain
A prospective, multicenter, self-control clinical trial aim to enroll 110 patients suffered from upper abdominal (liver, pancreas, stomach, etc.) cancers .
- Conditions
- Liver Cancer, Pancreas Cancer, Stomach Cancer, Bile Duct Cancer
- Trial name
- NCT04014478
- Testing
- Endovascular Denervation
- Volunteers
- 110 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Behavioural Insomnia of Childhood
A Longitudinal Study of Parental Sleep Intervention for Behavioral Insomnia in Early Childhood
The global incidence of mental illness among children and adolescents is rising, drawing increasing attention to early risk factors and preventive strategies.
- Trial name
- SuSleep (NCT07420504)
- Testing
- Parental sleep enhancement intervention
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Soochow University
Healthy Adult Participants
REM Enhancement Sleep Technology for Well-being, Emotion, and Life Lift
This study aims to explore the efficiency of a digital, Smartphone-delivered intervention for improving the quality of REM sleep on the mental health, emotion regulation and overall life quality of users.
- Trial name
- RESTWELL (NCT07589114)
- Testing
- Mobile smartwatch application.
- Where
- 2 sites in Romania
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Wet Age-related Macular Degeneration
This Study Will Compare the Efficacy and Safety of SCT510A Administered by Intravitreal Injection (IVT) With Ranibizumab in Patients With wAMD
The purpose of this study is to compare the efficacy and safety of SCT510A versus Lucentis in the treatment of wet age-related macular degeneration.
- Trial name
- NCT05480293
- Testing
- Ranibizumab, SCT510A
- Where
- China
- Volunteers
- 446 people
- Sponsor
- Sinocelltech Ltd.
Asthma, Quality of Life
Quality of Life Assessment in Greek asthmatIc Patients Treated With the Fixed Dose Combination of Budesonide / Formoterol in Clinical Practice
The greater efficacy of combination therapy led to the development of fixed combination devices which simultaneously carry both glucocorticosteroid and a LABA (eg stable combinations of fluticasone-salmeterol…
- Conditions
- Asthma, Quality of Life, Satisfaction
- Trial name
- SKIRON (NCT03055793)
- Testing
- budesonide formoterol fixed combination
- Where
- Greece
- Volunteers
- 1,400 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Hidradenitis Suppurativa (HS)
Participants with Mild to Moderate Hidradenitis Suppurativa Will Receive EVO101 a Topical Cream 0.1%
The goal of this clinical trial is to learn if drug EVO101 works to treat mild to moderate hidradenitis suppurativa in adults. The main questions it aims to answer are: Does drug EVO101 lower the total number of lesion a…
- Trial name
- NCT06645821
- Testing
- EVO101
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Virginia Clinical Research, Inc.
Anxiety, Obesity
Obesity and Mindful Eating in Patients With Anxiety
Background: Obesity is chronic disease with high prevalence rates, functional disability and difficult long-term management. Anxiety is one of the most common psychological disorders in obesity, and when associated with other…
- Conditions
- Anxiety, Obesity, Eating Behavior, Mindfulness
- Trial name
- OMETA (NCT06087185)
- Testing
- Mindful Eating, Video Group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Rumination, Cognitive Avoidance
The Effectiveness of Dialectical Behavior Therapy on Rumination and Cognitive Avoidance in Teachers
This randomized controlled trial evaluated the effectiveness of Dialectical Behavior Therapy (DBT) skills training in reducing rumination and cognitive avoidance among middle-school teachers in Isfahan, Iran.
- Trial name
- NCT07650617
- Testing
- Dialectical Behavior Therapy Skills Training
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Gastrointestinal Bleeding
Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding
This double-blind, randomized trial aims to evaluate whether uninterrupted anti-platelet therapy (clopidogrel) will increase the risk of bleeding associated with removal of polyp during colonoscopy in patients with coronary…
- Trial name
- NCT01806090
- Testing
- clopidogrel
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to
ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER.
Overall, only limited evidence exists regarding the clinical benefit of antithrombotic prophylaxis after laparoscopic surgery for cancer.
- Conditions
- The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to, Prophylaxis Given for 8±2 Days After Planned Laparoscopic, Surgery for Colorectal Cancer.
- Trial name
- PRO-LAPS I (NCT01589146)
- Testing
- Heparin, Low-Molecular-Weight
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Of Perugia
To Evaluate the Validity of the Measure Method, we Will Compare Vasculight v1.0 PWV Measures With Those Obtained From E-tracking (Echocardiographic Method).
Non-invasive Screening of the Status of the Vascular System: Feasibility Test
This project is part of the EU funded project NISTAS. NISTAS aims at the development of a new medical device for non-contact, non-invasive screening of the health status of the vascular system of adult subjects.
- Trial name
- NISTAS1 (NCT02392260)
- Testing
- Vasculight
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Chronic Myelogenous Leukemia
Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemia
The aim of this study is to demonstrate the safety and the efficacy of a combination of 2 treatments shown to have some efficacy in Chronic Phase Chronic Myelogenous Leukemia (CP CML) separately, but that have never been combined…
- Trial name
- NILOPEG (NCT01294618)
- Testing
- Nilotinib,Novartis,300 mg twice a day +Pegylated interferon 2a,Roche, 45 microg weekly starting Month 2-Month 12 or beyond according to investigator choice.
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
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