Clinical trials: Wisdom Teeth
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Impacted Mandibular Third Molar
Dexamethasone-PRF in Mandibular Third Molar Surgery: Effect on Pain, Edema, and Trismus (DEXPRF-3M)
Brief Summary This clinical trial investigates the effects of platelet-rich fibrin (PRF) derived from dexamethasone-enriched blood on postoperative recovery following the surgical extraction of impacted mandibular third molars…
- Trial name
- DEXPRF-3M (NCT07045350)
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Alveolar Osteitis, Impacted Tooth
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars.
- Trial name
- NCT04151147
- Testing
- Concentrated Growth Factor (Test group), Non-Concentrated Growth Factor (Control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Impacted Lower Third Molar
Antibiotic Therapy in Impacted Mandibular Third Molar Surgery
This study compared three antibiotic approaches in healthy young adults undergoing surgical removal of impacted lower wisdom teeth: a single dose of antibiotics before surgery, antibiotic treatment after surgery, and no…
- Trial name
- NCT07817940
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Class II Malocclusion
Effect of Maxillary Third Molar Extraction vs. Non-extraction on Distalization of First Molars in a Group of Adolescent Patients
There is a scarcity in literature regarding the influence of maxillary third molar on distalization . This study aimed to compare the influence of unerupted maxillary third molars and their extraction on the bilateral…
- Trial name
- NCT05647720
- Testing
- Distalization combined with upper third molars extraction, Distalization without upper third molars extraction
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Local Anesthetic Efficacy
Efficacy of Differents Anaesthetics in Mandibular Third Molar Germectomy
Aim: To compare the clinical efficacy of local anaesthetics with articaine 4% or mepivacaine 2% (both with epinephrine 1:100.000) using different anaesthetic techniques to perform germectomy of lower third molars and to assess…
- Trial name
- NCT04465149
- Testing
- Third Molar Germectomy
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Impacted Third Molar Tooth
Comparison of Two Different Flap Designs for Bilateral Impacted Mandibular Third Molar Surgery
The aim of this study was to compare the effects of lingually-based triangle flap design and buccally based triangular flap design on postoperative swelling, trismus pain after mandibular third molar surgery.
- Trial name
- NCT03784638
- Testing
- lingually-based triangle flap design, buccally based triangular flap design
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Pain, Postoperative, Narcotic Use
Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery
The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption.
- Trial name
- NCT04791943
- Testing
- Melatonin 10 MG, Lactose pill
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Impacted Third Molar Tooth
Does Extraction Difficulty of Mandibular Impacted Third Molars Mirror Post-op Outcomes?
The tooth of the patient who applies to the clinic for the impacted wisdom tooth will be classified according to Escoda's difficulty classification.
- Trial name
- NCT05049382
- Testing
- Extraction of impacted mandibular third molar
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Surgical Blood Loss, Third Molar
Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery
The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.
- Trial name
- NCT04143373
- Testing
- warm saline irrigation
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Impacted Third Molar Tooth
Evaluation of Preoperative Submucosal Dexamethasone in Third Molar Surgery
The study composed of sixty patients, each of whom required surgical extraction of a single impacted mandibular third molar under local anaesthesia. The patients were randomly allocated to one of 3 groups of 20 each.
- Trial name
- NCT02837614
- Testing
- dexamethasone acetate, submucosal dexamethasone injection, Third molar surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Impacted Wisdom Teeth
Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction
This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain.
- Trial name
- Caldolor (NCT02133326)
- Testing
- Caldolor, Ofirmev
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Tufts University School of Dental Medicine
Impacted Third Molar Tooth
Gum Health Gel in Post Extraction Sockets
This research studies the effectiveness of the Gum Health gel in minimizing post operative sequelae associated with the surgical removal of impacted mandibular third molars
- Trial name
- Gum Health gel (NCT06251141)
- Testing
- Gum Health gel, Gel foam
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Postoperative, Trismus
Comparison of the Effect of A-PRF and L-PRF on Outcomes After Removal of Impacted Mandibular Third Molar
In this study, it was aimed to investigating and comparing the postoperative effects of leukocyte- and platelet-rich fibrin (L-PRF) and advanced platelet-rich fibrin (A-PRF) in terms of pain, swelling on the cheek, and trismus…
- Conditions
- Pain, Postoperative, Trismus, Swelling
- Trial name
- NCT03672669
- Testing
- Advanced Platelet Rich Fibrin (A-PRF), Leukocyte- and platelet-rich fibrin (L-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Tooth Impaction, Tooth Diseases
Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery.
- Trial name
- NCT06067542
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Impacted Third Molar Tooth
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
Ginger contains constituents with pharmacological properties similar to the novel class of dual-acting NSAIDs. Compounds in this class inhibit arachidonic acid metabolism via the cyclooxygenase (COX) and lipooxygenase (LOX)…
- Trial name
- GPE (NCT01429935)
- Testing
- Ginger powder, Ibuprofen
- Where
- 2 sites in Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Photodynamic Therapy, Third Molar Extraction
The Effect of Photodynamic Therapy on Post-extraction Third Molar
The extraction of lower third molars is one of the most frequent procedures in oral surgery. For this reason, the extraction of these teeth generally requires a surgical approach involving the elevation of a mucoperiosteal flap…
- Conditions
- Photodynamic Therapy, Third Molar Extraction, Antimicrobial Photodynamic Therapy
- Trial name
- NCT06964178
- Testing
- Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Impacted Third Molar Tooth
Comparison of the Use of Dexamethasone and Diclofenac Sodium in Immediate Post-Operative Care in Third Molar Surgery
The investigators will select 30 patients with symmetrical impaction of third molars, according to Pell and Gregory dental impaction classification, who would be submitted to two surgical procedures, right and left, and in both…
- Trial name
- NCT02698306
- Testing
- Dexamethasone, Diclofenac Sodium
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Geral de Vila Penteado