Clinical trials: Wisdom Teeth
Trismus, Edema
Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surgery
The objective of this case-control intervention study is to explore the effectiveness of Concentrated Growth Factor (CGF) and Advanced Platelet Rich Fibrin (A-PRF) on Pain, Edema and Trismus After Impacted Lower Third Molar…
- Conditions
- Trismus, Edema, Pain, Post-Op Complication
- Trial name
- NCT03690167
- Testing
- Concentrated Growth Factor (CGF), Advanced Platelet Rich Fibrin (A-PRF), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Damla Torul
Impacted Third Molar Tooth, Pain, Acute
Variability in Analgesic Response to Ibuprofen
Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain.
- Trial name
- NCT06539741
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dental Anxiety
Evaluation on the Anxiety of Third Molar Extraction
This study was performed on 66 patients who were admitted for third molar extraction under local anesthesia. The patients were divided into three groups: group 1 with verbal information, group 2 with written information, and…
- Trial name
- NCT03838081
- Testing
- Spielberger State Anxiety Inventory (STAI-S),, Dental Fear Scale (DFS), Modified Dental Anxiety Scale (MDAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara University
Impacted Third Molar Tooth
Epidemiological Study on the Surgical Removal of Third Molars
The aim of this study is to get a clear view on current practice of surgical third molar removal in Belgium and the association with morbidity and complications.
- Trial name
- NCT02481700
- Testing
- Third molar removal
- Volunteers
- 6,010 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Impacted Mandibular Third Molar Extraction, Postoperative Pain Control
Evaluation of Corticosteroid Administration Following Impacted Third Molar Surgery Using 3-Dimensional Facial Analysis
The purpose of this prospective, randomized, controlled, single-blind clinical trial is to compare the efficacy of local submucosal administration of dexamethasone versus methylprednisolone on postoperative morbidity following…
- Conditions
- Impacted Mandibular Third Molar Extraction, Postoperative Pain Control, Postoperative Edema and Pain
- Trial name
- NCT07628166
- Testing
- Surgical Extraction of Impacted Mandibular Third Molar, methylprednisolone sodium succinate, Dexamethasone Sodium Phosphate Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Irfan Üstündağ
Impacted Third Molar Tooth
Comparison of The Surgical Drain Placement With Use of Kinesiologic Tape
The investigator's purpose was to compare the effects of the surgical drain and kinesiologic tape applications on postoperative morbidity after mandibular third molar surgery.
- Trial name
- NCT04108559
- Testing
- Kinesiologic Tape Group, Drain Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Impacted Third Molar Tooth
Assessment of the Relationship Between Edema Measurement Methods After Impacted Mandibular Third Molar Surgery.
The aim of this study is to evaluate the correlation between two point distance measurements performed by surgeon on patients face with foldable ruler, which is the most commonly used method, and the subjective scoring will be…
- Trial name
- NCT03747237
- Testing
- Edema measurement methods
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Alveolar Osteitis, Impacted Tooth
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars.
- Trial name
- NCT04151147
- Testing
- Concentrated Growth Factor (Test group), Non-Concentrated Growth Factor (Control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Impacted Mandibular Third Molar
Dexamethasone-PRF in Mandibular Third Molar Surgery: Effect on Pain, Edema, and Trismus (DEXPRF-3M)
Brief Summary This clinical trial investigates the effects of platelet-rich fibrin (PRF) derived from dexamethasone-enriched blood on postoperative recovery following the surgical extraction of impacted mandibular third molars…
- Trial name
- DEXPRF-3M (NCT07045350)
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Impacted Third Molar Tooth
Evaluation of the Effects of Silk and Polyester Suture on Postoperative Complications
Some undesirable complications such as pain, swelling, trismus, paresthesia, hematoma, infection and, albeit rare, fractures may occur after lower impacted wisdom tooth surgery.
- Trial name
- NCT05534204
- Testing
- Silk suture, Polyester suture
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Facial Swelling, Tooth Position Anomalies
Platelet-Rich Fibrin as an Antibiotic Delivery Vehicle in Mandibular Third Molar Surgery
The present study aims to evaluate the effect of platelet-rich fibrin (PRF) used as a local antibiotic delivery vehicle on postoperative outcomes, including facial swelling, trismus, and pain, following mandibular third molar…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT07764757
- Testing
- Antibiotic-enriched Platelet-Rich Fibrin (PRF), Platelet-Rich Fibrin (PRF)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Wound Heal
Effect of A-PRF After Removal of Wisdom Teeth
To evaluate the healing effect of advanced platelet-rich fibrin (blood clot charged with growth factors) taken from the patient own blood on the extraction site.
- Trial name
- A-PRF (NCT03703479)
- Testing
- autologous blood clot made from the patient own clot without any additive
- Where
- Saudi Arabia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pain, Other Surgical Procedures
Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery
Pharmacogenetics is an area of Pharmacology that studies the contribution of genetic factors to individual responses to drugs. This branch of science involves the variability in pharmacodynamics and pharmacokinetics through the…
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth, Cytochrome P450 CYP2C9 Enzyme Deficiency
- Trial name
- NCT02450487
- Testing
- Piroxicam
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Third Molars Extraction
Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars
This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal In this prospective, randomized controlled trial,130 patients who underwent mandibular third…
- Trial name
- RITOR (NCT06880952)
- Testing
- Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Isala
Tooth, Impacted, Wound Heal
Effect of Low Level Laser Therapy After Wisdom Tooth Removal
The aim is to test the effect of low level laser therapy on the relief of symptoms after wisdom tooth removal.
- Conditions
- Tooth, Impacted, Wound Heal, Quality of Life
- Trial name
- NCT04437316
- Testing
- Use of Low level Laser after wisdom tooth removal
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Ozone, Third Molar
Effects of Ozonated Water on Pain, Swelling, Trismus and Quality of Life in Third Molar Surgery
The aim of this study was to evaluate the effect of ozonated water on pain, edema and trismus after third molar removal. Patients were submitted to extraction of lower third molar under irrigation with ozonated water or doubly…
- Conditions
- Ozone, Third Molar, Clinical Trial
- Trial name
- NCT03501225
- Testing
- ozone, water
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Impacted Third Molar Tooth
Evaluation of the Efficacy of Polybutester Suture on Postoperative Complications in Lower Impacted Third Molar Surgery
This study aimed to evaluate the efficacy of polybutester sutures on postoperative complications in lower impacted third molar surgery.
- Trial name
- NCT05679973
- Testing
- Polybutester suture, Polypropylene suture
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University