Clinical trials: Wisdom Teeth
Impacted Third Molar Tooth
Pre Emptive Analgesics for Pain Relief in Impacted Lower Third Molar Surgery
The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale
- Trial name
- NCT04769557
- Testing
- paracetamol
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Dental Pain
Study of Naproxen Capsules to Treat Dental Pain
The purpose of the study is to determine whether Naproxen Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT01229228
- Testing
- Naproxen Test, Naprosyn
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Iroko Pharmaceuticals, LLC
Impacted Third Molar Tooth
Assessment of Vertical Pattern in Correlation With Third Molar Inclusion : A 3D CBCT Analysis
The objective is to compare the sagittal and vertical skeletal parameters of patients with an impacted third molar. Patients will be analyzed according to their skeletal characteristics: skeletal class (sagittal direction) and…
- Trial name
- NCT06320665
- Testing
- Radiographic measurement
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Oral Soft Tissue Conditions
Phytotherapy Agent in Third Molar Surgery
The aim of the present study was to evaluate the effect of a phytotherapy agent on clinical and inflammatory parameters, for the postoperative therapy of the impacted third molar surgery.
- Trial name
- NCT03335683
- Testing
- Lenidase
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gaetano Isola, DDS, PhD
Third Molars Extraction
Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia
The goal of this clinical trial is to compare the efficacy of bupivacaine and ropivacaine in third molar removal surgery under general anesthesia in healthy volunteers.
- Trial name
- NCT07108465
- Testing
- Bupivacaine 0,5%, Ropivacaine 0,75%
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Impacted Third Molar Tooth
Epidemiological Study on the Surgical Removal of Third Molars
The aim of this study is to get a clear view on current practice of surgical third molar removal in Belgium and the association with morbidity and complications.
- Trial name
- NCT02481700
- Testing
- Third molar removal
- Volunteers
- 6,010 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Surgery
Analgesic Effect of Ibuprofen, Paracetamol (Acetaminophen), and Paracetamol (Acetaminophen) Plus Codeine on Acute Pain
The purpose of this placebo controlled clinical trial is to evaluate the dose response relationship of ibuprofen in doses from 400 mg to 800 mg and paracetamol (acetaminophen)in doses from 500 mg to 1000 mg compared with…
- Trial name
- NCT00699114
- Testing
- Ibuprofen 400 mg, Ibuprofen 600 mg, Ibuprofen 800 mg
- Where
- Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Third Molar Surgery
Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative…
- Trial name
- NCT04200885
- Testing
- Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Poly(Lactide-co-glycolide) Sutures, Suture Resorption
Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.
This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis.
- Conditions
- Poly(Lactide-co-glycolide) Sutures, Suture Resorption, Third Molar Surgery
- Trial name
- NCT07498361
- Testing
- Fast absorbable sutures application, Standard absorbable sutures application
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Impacted Third Molar Tooth
Post-Surgical Morbidity and Bone Healing of Impacted Lower Third Molars: Piezosurgery vs. Conventional Instruments
The aim of this study is to compare piezosurgery and conventional surgery in impacted third molar surgery and to determine its effect on postoperative outcomes and quality of life.
- Trial name
- NCT06262841
- Testing
- Piezosurgery, Conventional burs
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Oral Complication
Effect of CGF on Postoperative Edema in Third Molar Surgery
The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on edema after bilateral impacted third molar surgery and to determine its contribution to the healing process.
- Trial name
- NCT06893523
- Testing
- Concentrated Growth Factor, Non-CGF
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ege University
Tooth Impaction, Tooth Diseases
Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery.
- Trial name
- NCT06067542
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Anxiety, Dental, Post Operative Pain
Effectiveness of Green Color Exposure on Dental Anxiety
The investigator's aim in this study was to evaluate the preoperative anxiety and the pain felt during the operation due to exposure to green light.
- Trial name
- NCT05584696
- Testing
- Green light exposure, Normal light exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Facial Swelling, Tooth Position Anomalies
Platelet-Rich Fibrin as an Antibiotic Delivery Vehicle in Mandibular Third Molar Surgery
The present study aims to evaluate the effect of platelet-rich fibrin (PRF) used as a local antibiotic delivery vehicle on postoperative outcomes, including facial swelling, trismus, and pain, following mandibular third molar…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT07764757
- Testing
- Antibiotic-enriched Platelet-Rich Fibrin (PRF), Platelet-Rich Fibrin (PRF)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Third Molars Extraction
Avatar-assisted Pre- and Post-operative Information Following Surgical Removal of a Mandibular Third Molar.
This study assess the efficacy of digital avatar-assisted pre- and post-operative information against nurse-led oral and written information following SRM3 including an analysis of potential risk factors associated with impaired…
- Trial name
- NCT07805304
- Testing
- Avatar-assisted pre- and post-operative information following surgical removal of an mandibular third molar
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Impacted Wisdom Teeth
Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction
This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain.
- Trial name
- Caldolor (NCT02133326)
- Testing
- Caldolor, Ofirmev
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Tufts University School of Dental Medicine
Postoperative Pain, Wisdom Tooth
Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
The purpose of this study is to investigate whether robust analgesic regime (protective analgesia) can improve postoperative pain experience for patients undergoing lower wisdom teeth extraction under day case general anaesthetic.
- Trial name
- NCT00895843
- Testing
- Brufen retard, ibuprofen, Bupivacaine
- Where
- 2 sites in United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Impacted Third Molar Tooth
Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus
The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar…
- Trial name
- NCT04534426
- Testing
- : Arnica montana, Mucopolysaccharide polysulfate, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University