Clinical trials: Wisdom Teeth
Clinical Efficacy of Submucosal Dexamethasone and Oral Trypsin Chymotrypsin for Reduction of Postoperative Sequelae After Lower Third Molar Surgery
Comparison of Clinical Efficacy of Submucosal Dexamethasone and Oral Trypsin-chymotrypsin for Reduction of Postoperative Sequelae After Lower Third Molar Surgery
Pain, edema and trismus are the most frequent postoperative sequelae to surgical removal of impacted teeth, all of are due to the local inflammatory response.
- Trial name
- NCT06713733
- Testing
- Dexamethasone, Chymotrypsin
- Where
- Nepal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Wisdom Tooth Removal, Dental Anesthesia
Effect of Subperiosteal Ropivacaine After Third Molar Extraction
This study examined whether an additional injection of the long-acting local anesthetic ropivacaine at the surgical site could reduce pain and improve recovery after removal of lower wisdom teeth.
- Conditions
- Wisdom Tooth Removal, Dental Anesthesia, Ropivacaine
- Trial name
- NCT07844824
- Testing
- Ropivacaine 0.75%, Saline (0.9% NaCl)
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Melatonin
Effects of Melatonin and Massage After Third Molar Surgery
Lymphatic drainage massage is an important practice, especially for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin surface.
- Trial name
- NCT06812026
- Testing
- no melatonin and massage, receive melatonin, receiving lymphatic drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Anxiety, Dental Fear
The Effect of Conscious Sedation on Acute Stress
The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship…
- Conditions
- Dental Anxiety, Dental Fear, Tooth Extraction Status Nos
- Trial name
- NCT04207515
- Testing
- Procedures of wisdom tooth removal surgery under conscious sedation, Procedures of wisdom tooth removal surgery under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Post Operative Swelling, Impacted Mandibular Third Molar Extraction
THE COMPARISON OF GELATIN SPONGE TO SUTURE ALONE ON POST OPERATIVE SWELLING AFTER EXTRACTION OF IMPACTED MANDIBULAR THIRD MOLAR.
This Study is designed for purpose to increase patient safety and reduce complications which occurs after mandibular 3rd molar extraction which is will increase discomfort after extraction.
- Trial name
- Gelatin Sponge (NCT07306403)
- Testing
- Gelatin Sponge Sheet, Swelling
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Surgical Blood Loss, Third Molar
Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery
The objective of this research is to compare the effect of irrigation during impacted mandibular third molar surgery, with normal saline of 25 ± 2 ° C and 37 ± 1 ° C for control and experimental sides, respectively.
- Trial name
- NCT04143373
- Testing
- warm saline irrigation
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Alveolitis of Jaw, Alveoli, Teeth; Inflammation
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals.
- Conditions
- Alveolitis of Jaw, Alveoli, Teeth; Inflammation, Dry Socket, Impacted Third Molar Tooth
- Trial name
- AITS (NCT03741894)
- Testing
- Iodoform, Wound closure using sutures, Chlorhexidine
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Impacted Third Molar Tooth
Effect of Honey and Dexamethason on Extraction Healing
Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated
- Trial name
- NCT04848259
- Testing
- Normal saline, Dexamethasone, Honey
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Poly(Lactide-co-glycolide) Sutures, Suture Resorption
Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.
This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis.
- Conditions
- Poly(Lactide-co-glycolide) Sutures, Suture Resorption, Third Molar Surgery
- Trial name
- NCT07498361
- Testing
- Fast absorbable sutures application, Standard absorbable sutures application
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Oral Soft Tissue Conditions
Phytotherapy Agent in Third Molar Surgery
The aim of the present study was to evaluate the effect of a phytotherapy agent on clinical and inflammatory parameters, for the postoperative therapy of the impacted third molar surgery.
- Trial name
- NCT03335683
- Testing
- Lenidase
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gaetano Isola, DDS, PhD
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Pain
Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction
The goal of this clinical trial is to test the ability of HT-6184 to decrease inflammation and pain in patients after third molar removal.
- Trial name
- NCT06241742
- Testing
- HT-6184
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Halia Therapeutics, Inc.
Root Resorption, Distal Caries
Frequency of External Root Resorption in Mandibular Second Molars Associated With Mandibular Impacted Third Molars Using CBCT
The prevalence of external root resorption and distal caries in mandibular second molars associated with impacted mandibular third molars will be detected in addition to the association of the risk factors.
- Trial name
- NCT03981367
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain, Postoperative
A COMPARISON OF TRANSDERMAL DICLOFENAC AND ORAL COMBINATION OF PARACETAMOL AND IBUPROFEN IN POSTOPERATIVE PAIN MANAGEMENT FOLLOWING SURGICAL EXTRACTION OF MANDIBULAR THIRD MOLAR- A RANDOMISD CONTROLLED TRIALS.
This is comparative interventional study, will be conducted in patient indicated for surgical extraction of mandibular third molar at the Department of Oral and Maxillofacial surgery, College of Dental Surgery, BPKIHS, Nepal.
- Trial name
- NCT06146491
- Testing
- Oral tablet and transdermal patch
- Where
- Nepal
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Tooth Disease, Piezoelectric Technique
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
The main objective of the study is to compare the effects of the piezoelectric surgery and the traditional technique on soft tissue edema in patients undergoing bilateral germectomy of mandibular third molars
- Conditions
- Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
- Trial name
- Germectomy (NCT06778590)
- Testing
- Piezoelectric technique in third molar germectomy, Traditional technique in third molar germectomy
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Teeth, Impacted
Bupivacaine in the Treatment of Postoperative Pain of Impacted Third Molar Extraction
The third molars are the teeth that are most frequently included and impacted, extraction is one of the most performed treatments by maxillofacial surgeons in their clinical practice.
- Trial name
- NCT03950700
- Testing
- Bupivacaine-epinephrine, Saline Solution
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing
Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars.
- Trial name
- NCT07318298
- Testing
- Surgical extraction of wisdom teeth, bone biobsy
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Pain
Study of Naproxen Capsules to Treat Dental Pain
The purpose of the study is to determine whether Naproxen Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT01229228
- Testing
- Naproxen Test, Naprosyn
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Iroko Pharmaceuticals, LLC
Wisdom Teeth
Evaluation of the Effect of Circadian Rhythm of Adrenal Glucocorticoids After Third Molar Extraction
This study aimed to investigate the effects of wisdom tooth surgery performed at different times of the day on pain, swelling and trismus based on changes in the circadian rhythm in the adrenal glands in patients aged between…
- Trial name
- NCT06610383
- Testing
- Surgical extraction of wisdom teeth in the morning, Surgical extraction of wisdom teeth in the afternoon
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University