Clinical trials: Wisdom Teeth
Third Molar Surgery, Post Operative Analgesia
'Propolis Versus Chlorhexidine Gluconate on Wound Healing After Third Molar Surgery: a Randomized Controlled Trial'
The goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate.
- Trial name
- NCT07364253
- Testing
- Third molar Surgery with propolis gargle, Third molar surgery with chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Tooth Impaction, Tooth Diseases
Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery.
- Trial name
- NCT06067542
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Oral Complication
Effect of Piezoelectric Surgery onPostoperative Complications in Third Molar Surgery
The purpose of this study is to compare the effects of piezoelectric surgery on postoperative edema, trismus and other postoperative complications (Wound Healing, Bleeding, Infection, Alveolitis, Paresthesia) with conventional…
- Trial name
- NCT06965855
- Testing
- conventional surgery, piezoelectric surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Orthodontic Treatment Via Premolar Extraction
Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars
What is the effect of extraction orthodontic treatment in comparison to non- extraction treatment on the position, inclination and incidence of impaction of the third molars?
- Trial name
- NCT04857658
- Testing
- extraction orthodontic treatment plan
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Substance Use
iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery
This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and their parents.
- Trial name
- iPAWS (NCT07731295)
- Testing
- iPAWS, Educational Materials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain, Post-operative
Multimodal Analgesic Protocol to Moderate Acute Pain
With a prospective, observational study assess post-surgery pain levels and patient's use of opioids and other analgesic drugs to moderate pain following third molar surgery.
- Trial name
- NCT03456141
- Testing
- third molar surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Surgical Wound, Healed, Post Operative Pain
Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars
Brief summary The goal of this study is to compare the effects of advanced platelet rich fibrin and enamel matrix derivative placed in the extraction alveoli of patients who had surgical removal of mandibular wisdom teeth.
- Trial name
- NCT06190015
- Testing
- Advanced platelet rich fibrin (APRF) clots, Enamel matrix derivative (EMD) group
- Where
- Serbia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Tooth, Impacted
Piezoelectric Vibrations and Tissue, Cellular and Molecular Mechanisms of Oral Wound Healing After Third Molar Surgery
The aim of this clinical trial is to investigate and compare the effect of piezoelectric surgery on tissue, cellular and molecular level of oral surgical wound healing and postoperative outcomes (pain, swelling, trismus) after…
- Trial name
- NCT02942108
- Testing
- piezo surgery, conventional surgery
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Impacted Third Molar Tooth
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
Ginger contains constituents with pharmacological properties similar to the novel class of dual-acting NSAIDs. Compounds in this class inhibit arachidonic acid metabolism via the cyclooxygenase (COX) and lipooxygenase (LOX)…
- Trial name
- GPE (NCT01429935)
- Testing
- Ginger powder, Ibuprofen
- Where
- 2 sites in Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Dry Socket, Wound Infection
Triclosan Toothpaste and Third Molar Surgery
Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.
- Trial name
- NCT01292343
- Testing
- Colgate Total Toothpaste, Colgate Regular Toothpaste
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Molar, Third, Third Molar Surgery
3D Evaluation of Postoperative Edema After Third Molar Surgery
Surgical removal of third molars is recognized as one of the most frequent procedures performed in oral surgery. Literature is rich in studies attempting to demonstrate the benefit of corticosteroids in third molar surgery…
- Conditions
- Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative
- Trial name
- NCT05941130
- Testing
- Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Postoperative Pain, Postoperative Complications
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars.
- Conditions
- Postoperative Pain, Postoperative Complications, Trismus, Periodontal Health
- Trial name
- NCT07180498
- Testing
- Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Harran University
Pain
Evaluation of the Effectiveness of the Use of the Therapeutic Bandage Method in Third Molar Surgery
Extraction of lower third molars semi-included or included is one of the most performed procedures in oral surgery, and inherent to the procedure there is a postoperative inflammatory response.
- Trial name
- NCT03393533
- Testing
- Group I, Group II
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Pain, Postoperative, Narcotic Use
Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery
The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption.
- Trial name
- NCT04791943
- Testing
- Melatonin 10 MG, Lactose pill
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Impacted Third Molar Tooth, Adverse Reaction to Other Local Anesthetics
Lower Third Molar Removal With 2% and 4% Articaine
The present clinical trial randomized compared the clinical efficacy of the local anesthetics articaine in two concentrations, 2% and 4%, in association with 1:200,000 adrenaline, for the removal of lower third molars.
- Trial name
- NCT02457325
- Testing
- Surgery with 2%Articaine first, then Surgery with 4% Articaine, Surgery with 4%Articaine first, then Surgery with 2% Articaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Molar, Third, Pain
Influence of CYP2C9 Genotype on Clinical Efficacy of Tenoxicam
The goal of this study is to evaluate the different gene haplotypes for the clinical efficacy of tenoxicam after third lower molar surgery for pain, edema and trismus, adverse reactions, need of rescue medication, patient…
- Trial name
- NCT04182191
- Testing
- Tenoxicam
- Where
- Brazil
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
TMJ, Apical Periodontitis
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional…
- Conditions
- TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth
- Trial name
- NCT05439330
- Testing
- MRI of teeth and surrounding structures
- Where
- Denmark
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Impacted Third Molar, Impacted Third Molar Tooth
Prospective Evaluation of Efficacy of Tumescent Steroid Infiltration in Mandibular Third Molar Surgery: a Split Mouth Randomized Study
The aim of this study is to evaluate the efficacy of tumescent solution on post operative sequalae in patients treated for surgical removal of impacted lower third molar. The objectives are Primary Objective 1.
- Conditions
- Impacted Third Molar, Impacted Third Molar Tooth, Third Molar Extraction, Third Molar Extraction Surgery
- Trial name
- NCT07436546
- Testing
- Tumescent Infiltration (dexamethasone, bupivacaine, adrenaline, hyaluronidase, saline), 2% lignocaine with adr (1:2,00,000)
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak