Clinical trials: Withdrawing Treatment
Post Traumatic Stress Disorder
Written Document to Assist Family During Decision of Withholding and Withdrawing Life-sustaining Therapies in the Intensive Care Unit
Relatives of patients in situation of withholding and withdrawing life-sustaining therapies often show post traumatic stress disorder (PTSD) (60%)[1].
- Trial name
- LATA (NCT02329418)
- Testing
- Explaining withholding and withdrawing life-sustaining therapies along with a written document, Explaining withholding and withdrawing life-sustaining therapies following standard procedure
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
End of Life
Impact of a Protocol for Announcing Decision of Withholding and Withdrawing Life-sustaining Treatments on the Stress of the Relatives in the Emergency Departments
Death is a daily reality in the emergency department. Deaths represent 0.3 to 0.5% of emergency admissions, i.e. approximately 26,000 per year for the whole of France.
- Trial name
- DISCUSS (NCT06071078)
- Testing
- Training of professionals according to the DISCUSS announcement protocol
- Where
- 9 sites in France
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Withdrawing Treatment
Donors After Cardiac Death: Validating Identification Criteria
The purpose of this study is to validate a set of proposed clinical criteria that have been designed to identify patients who will die rapidly following the elective removal of life sustaining treatments.
- Trial name
- NCT00177606
- Testing
- withdrawal of life sustaining treatments
- Where
- 4 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Pittsburgh
Intensive Care Units, Family's Satisfaction
Withholding or Withdrawing of Life-sustaining Therapy in Great East French Region Intensive Care Units: a 1-month Survey
Intensive care has known an important scientists progress for the last twenty years, allowing to heal more and more severe patients.
- Conditions
- Intensive Care Units, Family's Satisfaction, Therapy Decisions
- Trial name
- LATA (NCT05465187)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 78 people
- Sponsor
- CHU de Reims
Cardiopulmonary Arrest Outcome
Optimizing Resuscitation After Cardiac Arrest in the Community
Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage.
- Trial name
- NCT00998140
- Where
- Israel
- Volunteers
- 1,600 people
- Sponsor
- Shaare Zedek Medical Center
WITHOLDING WITHDRAWING in End of Life Situation
Withholding and/or Withdrawing Life-sustaining Treatment on Emergency Department Patients' Short- and Long-term Outcomes
Background In France, a significant proportion of end-of-life (EOL) decisions occur in emergency departments (EDs), where time constraints and limited resources may hinder optimal care.
- Trial name
- NCT07115719
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Beaujon Hospital
Medical Students in Intensive Care Unit
Serious Game-Based Training for Withholding and Withdrawing Life-Sustaining Treatments in the ICU
Background: Withholding and withdrawing life-sustaining treatments (WWLST) are frequent in ICU and raise important ethical, legal, and communication issues. Despite their importance, specific training on WWLST remains limited.
- Trial name
- HUGS (NCT07812727)
- Testing
- serious game (SG) on WWLST, powerpoint lecture (PPL) on WWLST
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
In Vitro Fertilization
Comparing Coasting by Withholding GnRH Agonist With GnRH Antagonist
Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of ovulation induction and is a life threatening iatrogenic complication.
- Trial name
- NCT01347268
- Testing
- GnRH antagonist, withdrawing GnRH agonists
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Axial Spondyloarthritis
Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis
The objective of this multicenter, randomized, double-blind study was to evaluate the efficacy and safety of continuing versus withdrawing therapy with adalimumab 40 mg given every other week SC in maintaining remission in…
- Trial name
- NCT01808118
- Testing
- adalimumab
- Volunteers
- 673 people
- Sponsor
- AbbVie
Acute Respiratory Failure, Cancer
Oxygenation Methods and Non-invasive Ventilation in Patients With Acute Respiratory Failure and a do Not Intubate Order
ICU care of patients considered "palliative" but without contraindications to admission to intensive care, for whom a do-not intubate order decision was made upon admission represents a particular target for non-invasive…
- Conditions
- Acute Respiratory Failure, Cancer, Hematologic Malignancy, Cardiac Insufficiency
- Trial name
- OXYPAL (NCT03673631)
- Testing
- NIV, NFHC-O2
- Where
- France
- Volunteers
- 330 people
- Sponsor
- Poitiers University Hospital