Clinical trials: Women Infertility
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Infertility
The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve
The uterine leiomyoma is the most common female benign disease.UPA seems to be most effective for the medical management of fibroids and could be place as preoperative adjunct to surgery but also as medical therapy to avoid…
- Trial name
- UPA_ovAge (NCT02361892)
- Testing
- ulipristal acetate
- Where
- Italy
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Infertility
Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women
The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
- Trial name
- NCT02219425
- Testing
- endometrial biopsy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Female Infertility, Gene Deregulation
Characterization of Methylation Pattern in Human Germ Cells of Patients Undergoing ICSI Treatment
There is increasing evidence that exposure to environmental factors in early development is associated with an increased risk of metabolic and other common diseases.
- Trial name
- NCT03565107
- Where
- Germany
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Obesity & Overweight, Infertility, Female
Dietary Reversal of the Reprometabolic Syndrome
This study proposes to test the specific question that a eucaloric, low-fat diet given to women with obesity will result in an increase in reproductive hormones.
- Trial name
- LFD (NCT07227766)
- Testing
- Low-fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infertility, Female
Success Rate Natural Cycles Versus Modified Natural Cycles in Frozen Embryos
There has been a recent significant increase in the frozen embryo replacement (FER) cycles due to freeze-all cycles to decrease the risk of ovarian hyperstimulation syndrome.
- Trial name
- NCT03798886
- Testing
- natural cycle, modified natural cycle, embryo transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Non Specific Chronic Endometritis, Infertility, Female
Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis
Infertile women undergoing hysteroscopy for diagnostic or therapeutic indication are asked to donate a sample of endometrium. Endometrial samples of study participants are examined for signs of chronic endometritis by…
- Trial name
- endoMB (NCT04103242)
- Testing
- 16s rRNA gene sequencing
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Childbearing, Delayed, Marriage Age
Youth Outlook on Life Opportunities Study
Singapore's fertility rate is currently below 1.2, raising concerns about population ageing and long-term sustainability. The fertility decline is characterized by falling birth rates among women in their 20s with almost no…
- Conditions
- Childbearing, Delayed, Marriage Age, Educational Problems, Anxiety
- Trial name
- NCT05026619
- Testing
- Information about age-related fertility, Information about policy initiatives, Information about diabetes
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Infertility, Female
Laparoscopy in Failed IVF
Current in-vitro fertilization (IVF) consumers are enjoying better success rates than early seekers, but only about a quarter of IVF cycles result in a live birth and many patients remain infertile after multiple IVF attempts.
- Trial name
- NCT06165484
- Testing
- laparoscopy and hysteroscopy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
Follicular Flushing Versus Direct Aspiration
The purpose of this study is to investigate the impact of follicular flushing on the oocyte recovery rate, oocyte maturity, fertilization rate, and embryo development and utilization as compared to direct aspiration (no flushing)…
- Trial name
- NCT03354858
- Testing
- Follicular flushing
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility, Female
Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness
One hundred thirty women with unexplained infertility participated in a prospective clinical study. Patients were assigned at random to one of two groups.
- Trial name
- NCT05846906
- Testing
- Sildenafil Citrate, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Infertility, Female
Topical Analgesia for Pain Relief in Hysterosalpingography
The study will involve giving topical analgesia or placebo and then assessing pain and satisfaction during and after the procedure in order to see wed to the placebo.hether the topical analgesia has helped in decreasing pain…
- Trial name
- HSG (NCT03802032)
- Testing
- Lidocaine Gel, KY jelly
- Where
- Nigeria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Healthy Women, Infertility, Female
Assess the Effect of Dehydroepiandrosterone (DHEA) or Other Androgenic Agents Over Markers of Ovarian Reserve
This study was conducted to evaluate the effect of a continuous administration of dehydroepiandrosterone (DHEA) or other androgenic agents on ovarian reserve markers in women with diminished ovarian reserve (ROD), such as antral…
- Trial name
- NCT02268032
- Testing
- DHEA, Another Androgenic Agent (VRaA), Fixed combination of 2 androgenic agents (VR2A)
- Where
- Chile
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Infertility
Mechanisms of Infertility and Hormonal Changes in Patients With Chronic Kidney Disease
Patients with chronic kidney disease (both men and women), especially those with terminal renal failure, manifest infertility. There has been demonstrated several hormonal changes in patients on dialysis.
- Trial name
- NCT01294904
- Where
- 2 sites in Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Anovulatory Infertility Related to Polycystic Ovary Syndrome
Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS
Anovulatory infertility is a common feature of the polycystic ovary syndrome (PCOS). Even if several first-step treatments have been proposed for anovulatory infertile PCOS patients, very few data are available in literature…
- Trial name
- NCT00461643
- Testing
- Clomiphene citrate, metformin, metformin plus clomiphene citrate, gonadotropins
- Where
- 3 sites in Italy
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Urologic Diseases, Male Infertility
Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients
Prospective observational study on the quality of life of patients attending general urology, sexual medicine, reproductive medicine, functional urology, neuro-urology and uro-oncology clinics.The data relating to the clinical…
- Conditions
- Urologic Diseases, Male Infertility, Sexual Medicine
- Trial name
- NCT06193850
- Testing
- Observation during time
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele