Clinical trials: Women Infertility
Mrk Anomaly, Infertility, Female
Uterus Transplantation LD - Feasibility Study - Sahlgrenska - BMC
Medical know-how concerning uterus transplantation will be transferred to new site by structured process involving theory, animal workshops and a clinical feasibility study on human subjects.
- Trial name
- GOT-BMC-UTx (NCT03590405)
- Testing
- uterus transplantation surgery and IVF
- Where
- 2 sites in Sweden
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Infertility, Ovulation Induction
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Efficacy and safety studies in the past have suggested that a starting dose of 75 International Unit (IU) of SJ-0021, and an increase in the dose by 37.5 IU every 7 days, are safe for treatment of subjects with ovulatory…
- Trial name
- NCT01185782
- Testing
- Gonalef® (Follitropin alfa), Purified pituitary gonadotropin (Fertinorm-P®)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Unrecognized Condition
The Effect of Melatonin Supplementation on Cumulus Cells and IVF Outcomes
This study investigates the effects of melatonin supplementation on cumulus cell gene expression and in vitro fertilization (IVF) outcomes in women over 35 years old.
- Trial name
- NCT06546774
- Testing
- Melatonin
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Infertility
The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization
This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.
- Trial name
- NCT06319573
- Testing
- Counseling Supported by Univfy® Report, Standard Counseling
- Where
- 2 sites in Spain
- Volunteers
- 366 people
- Sponsor
- Ginefiv
Infertility, Female, Genital Tuberculoses, Female
The Prevalence and Reproductive Outcome of Infertile Women With Genital Tuberculosis
Female genital tuberculosis infection (FGTB) is an important cause of female infertility in TB-endemic areas. The pregnancy rate of assisted reproductive treatment (ART) in the infertile women with FGTB is still unsatisfied even…
- Trial name
- TB-PRIME (NCT05311423)
- Testing
- QuantiFERON-TB test & endometrial pathology & endometrial tissue GeneXpert Ultra
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Huashan Hospital
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
Infertility, Female
Effects of Vitamin D Status on the Outcome of Ivf - Embryo Transfer
At present, there is no agreement on the effect of vitamin D level in serum and follicular fluid on the outcome of IVF-ET pregnancy.
- Trial name
- NCT03503006
- Where
- China
- Volunteers
- 2,569 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility
IVF Treatment in Women With Immature Oocytes in Previous Cycle
In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge.
- Trial name
- NCT02368964
- Testing
- GnRH agonist 0.2 mg + hCG 250 mcg, high dose hCG 500 mcg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Infertility, Female
Half-dose vs Conventional-dose Cetrorelix in ICSI Cycles
This prospective cohort study aims to compare the effectiveness of half-dose (0.125 mg/day) versus conventional-dose (0.25 mg/day) cetrorelix in GnRH antagonist ICSI cycles regarding clinical pregnancy rate in women with BMI ≥25…
- Conditions
- Infertility, Infertility, Female, Anovulation
- Trial name
- NCT07836400
- Volunteers
- 160 people
- Sponsor
- Assiut University
Endometriosis, Adenomyosis
Clinical and Molecular Study of Endometriosis and Adenomyosis
The purpose of this study is to determine whether endometriosis and adenomyosis are progressive diseases, in terms of symptoms (pain, abnormal uterine bleeding and infertility), anatomical lesions size, and recurrences.
- Trial name
- ENDOCHAP (NCT04481321)
- Testing
- Biological/Vaccine
- Where
- France
- Volunteers
- 5,300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism
Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism
The goal of this randomized controlled trial is to compare letrozole alone versus letrozole plus levothyroxine for ovulation induction in infertile women with both PCOS and subclinical hypothyroidism.
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism, Female Infertility
- Trial name
- NCT06041204
- Testing
- Letrozole 2.5mg, Levothyroxine 25 Mcg (0.025 Mg) Oral Tablet
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Infertility, Intrauterine Adhesions
Treatment of Infertility by Collagen Scaffold Loaded With Autologous Bone Marrow Stem Cells
Study of the treatment of infertility caused by severe intrauterine adhesions or endometrial dysplasia by collagen scaffold loaded with autologous bone marrow stem cells, and to provide clinical evidence for the treatment of…
- Conditions
- Infertility, Intrauterine Adhesions, Endometrial Dysplasia
- Trial name
- NCT02204358
- Testing
- autologous bone marrow stem cells
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Female Infertility Due to Diminished Ovarian Reserve
Microflare Protocol in Poor Responders
The effect of use of the microflare down regulation protocol on the outcome of the IVF/ICSI cycles in poor responders
- Trial name
- NCT02185326
- Testing
- Growth hormone (Norditropin, Novo nordisk)
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Woman's Health University Hospital, Egypt
Infertility, Invitro Fertilization
Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure
Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will…
- Trial name
- NCT02329197
- Testing
- Human Chorionic Gonadotropin (HCG)
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Mansoura University
Infertility, Emotional Disorder
Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
The main aim of this pilot study is to study the clinical utility and acceptability of a transdiagnostic psychological intervention, the Unified Protocol, delivered in online format to prevent the onset of emotional disorders in…
- Conditions
- Infertility, Emotional Disorder, Anxiety Depression
- Trial name
- RE-FER moodle (NCT06420674)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Jorge Javier Osma López
Infertility, Female
Agonist Trigger With HCG Luteal Supplementation vs HCG Trigger With Progesterone Luteal Supplementation in Antagonist Controlled HyperstimulationCycle
The aim of the current study is to compare agonist trigger and HCG luteal support vs standard HCG trigger and progesterone luteal supplementation in antagonist controlled hyperstimulation cycle as regards to clinical pregnancy…
- Trial name
- NCT04846218
- Testing
- hCG, Progesterone, Triptorelin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Infertile Women Undergoing IVF or ICSI
Postbiotic Intervention on Vaginal Microbiota
This study investigates the effects of postbiotic intervention on vaginal microbiota in infertile patients. Using a pre-post test design, we will enroll 15 women aged 30-45 years with at least two IVF failures.
- Trial name
- NCT07278024
- Testing
- postbiotics
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Anxiety, Stress
Aromatherapy for Mental Health Promotion in IVF Patients
The experience of infertility can cause significant emotional instability, especially for patients awaiting In Vitro Fertilization (IVF) treatment, generating anxiety, stress, and depressive symptoms.
- Conditions
- Anxiety, Stress, Depression Disorder, Quality of Life
- Trial name
- NCT07480668
- Testing
- Lavender essential oil Inhalation, Synthetic lavender aroma inhalation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of Minas Gerais
Infertility, Ovarian Hyperstimulation Syndrome
Short Versus Long Protocol for IVF and IVF+ICSI
Purpose: Comparing a GnRH agonist and an antagonist protocol for IVF/ICSI with regard to 1. frequency of ovarian hyperstimulation syndrome (OHSS) (1. outcome measure) 2. quality of life (2. outcome measure) 3. live birth rate (2.
- Conditions
- Infertility, Ovarian Hyperstimulation Syndrome, Quality of Life, Live Birth
- Trial name
- KvL (NCT00756028)
- Testing
- Patients receiving short protocol IVF/ICSI-treatment., Long protocol
- Where
- 2 sites in Denmark
- Volunteers
- 1,099 people
- Sponsor
- Peter Hornnes, MD, DMSc