Clinical trials: Women With Multiple Sclerosis
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Systemic Lupus Erthematosus (SLE), Lupus Nephritis (LN)
A Study to Evaluate MTM-H-001 Injection in Adult Patients With B-Cell-Related Autoimmune Diseases
This is an investigator-initiated, open-label, single-arm, dose-escalation and dose-expansion study to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of MTM-H-001 in adult participants with B-cell-related…
- Conditions
- Systemic Lupus Erthematosus (SLE), Lupus Nephritis (LN), Multiple Sclerosis, Myasthenia Gravis (MG)
- Trial name
- ArchAid-002 (NCT07593911)
- Testing
- MTM-H-001 Injection
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing GoBroad Hospital
Multiple Sclerosis, Bladder Dysfunction
Comparison of Craniosacral Therapy vs Pelvic Floor Physical Therapy
The purpose of this study is to determine the efficacy of CST for the treatment of LUTS in patients with MS and evaluate the acute effects compared to PFPT. A.
- Conditions
- Multiple Sclerosis, Bladder Dysfunction, Urinary Incontinence, Overactive Bladder
- Trial name
- NCT03213522
- Testing
- Pelvic Floor Physical Therapy, Craniosacral Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CentraState Medical Center
Multiple Sclerosis
Exploring Reproductive Decision-Making Among Women With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic disease that mainly affects young adults, including women during their reproductive years. Women with MS may face important questions and concerns related to marriage, fertility, pregnancy…
- Trial name
- NCT07829822
- Volunteers
- 272 people
- Sponsor
- Assiut University
Multiple Sclerosis (MS) - Relapsing-remitting
Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: The ADVICE Protocol Study (Phase 1)
This phase of the project aims to analyze the interaction between physical exercise and the phases of the menstrual cycle, evaluating its impact on fatigue, functional capacity, and exercise perception in women with and without…
- Trial name
- ADVICE Phase 1 (NCT06925022)
- Testing
- Strength training session during Early Follicular Phase, Strength Training Protocol during Late Follicular Phase, Strength Training during Mid-Luteal Phase
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Multiple Sclerosis
Tai Chi and Square-Stepping Exercises in Women With Multiple Sclerosis
Tai Chi is an exercise approach consisting of slow and controlled movements, whereas square stepping exercises are an exercise method in which specific step patterns are followed.
- Trial name
- NCT07461987
- Testing
- Tai Chi, Square Stepping Exercise (SSE), Home-based Frenkel Coordination Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Pamukkale University
Multiple Sclerosis, Urinary Bladder, Overactive
Wearables for the Bladder: an In-home Treatment Feasibility Pilot Study
The goal is to investigate the feasibility and effects of adding "wearables for the bladder" devices to conventional pelvic floor physical therapy (PFPT) to bladder function, in people with multiple sclerosis (MS).
- Trial name
- WeB (NCT05715268)
- Testing
- WeB, Standard pelvic floor physical therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Multiple Sclerosis
A Study of Disease Modifying Therapy Use in Women With Multiple Sclerosis Before, During, and After Pregnancy
This study aims to assess the real-world patterns of disease modifying therapy (DMT) use before, during, and after pregnancy in women with multiple sclerosis (MS).
- Trial name
- NCT07844070
- Where
- United States
- Volunteers
- 2,607 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis, Female Sexual Dysfunction
The Effect of Sexual Counseling With the PLISSIT Model on Sexual Function and Sexual Quality of Life in Women With Multiple Sclerosis: A Randomized Controlled Study
Multiple Sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system that is common in young ages and women.
- Trial name
- NCT06004518
- Testing
- sexual counselling with PLISSIT model
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University
Multiple Sclerosis
Virtual Reality in the Treatment of Pelvic Floor Dysfunction in Women With Multiple Sclerosis
The purpose of the current randomized clinical trial was to compare the effectiveness of virtual reality versus posterior tibial nerve stimulation on the improvement of pelvic floor dysfunctions in women with multiple sclerosis.
- Trial name
- NCT06576947
- Testing
- Virtual reality, Neuromodulation of the tibialis posterior nerve, Pelvic floor muscle training
- Volunteers
- 45 people
- Sponsor
- Universidad de Almeria
Overactive Bladder, Multiple Sclerosis
Transcutaneous Tibial Nerve Stimulation of Patients With Overactive Bladder (OAB) Syndrome
Tibial nerve stimulation (TNS) has been recognised as a safe and effective treatment for the management of overactive bladder (OAB) symptoms.
- Trial name
- NCT02790307
- Testing
- The Geko
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Multiple Sclerosis, Neurogenic Bladder
Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis
A clinical study to evaluate the efficacy and safety of solifenacin in patients with bladder symptoms due to spinal cord injury or multiple sclerosis
- Conditions
- Multiple Sclerosis, Neurogenic Bladder, Spinal Cord Diseases
- Trial name
- SONIC (NCT00629642)
- Testing
- Solifenacin Succinate, Oxybutynin Hydrochloride
- Where
- 39 sites in Australia, Belgium and 9 more
- Volunteers
- 249 people
- Sponsor
- Astellas Pharma Inc
Multiple Sclerosis, Overactive Bladder Syndrome
Effect of TTNS and PNS on Neurogenic Overactive Bladder Symptoms in Female Patients With Multiple Sclerosis.
This study aims to evaluate the use of transcutaneous tibial nerve stimulation (TTNS) and parasacral nerve stimulation (PSS) methods in the treatment of overactive bladder (OAB) symptoms in patients with Multiple Sclerosis (MS)…
- Trial name
- NCT06143397
- Testing
- TTNS (Transcutaneous tibial nerve stimulation), PNS (Parasacral nerve stimulation), Behavioral treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Multiple Sclerosis
Role of Neuromuscular Junction Function in Motor Fatigue in Multiple Sclerosis
This pilot study will evaluate for the presence of neuromuscular junction (NMJ) defect in women with motor fatigue in multiple sclerosis by Single Fiber Electromyography (SFEMG) using the concentric needle electrode.
- Trial name
- NCT02418897
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Autoimmune Diseases, Systemic Lupus Erthematosus (SLE)
CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease
CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B cell mediated autoimmune disease.
- Conditions
- Autoimmune Diseases, Systemic Lupus Erthematosus (SLE), Multi-Drug Resistant Nephrotic Syndrome, IgA Nephropathy (IgAN)
- Trial name
- NCT07305116
- Testing
- UCAR T-cell
- Where
- China
- Volunteers
- 15 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Multiple Sclerosis, Urinary Incontinence (UI)
URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS
This study aims to investigate the relationship between urinary incontinence severity and surface electromyography (EMG) findings in women with multiple sclerosis.
- Trial name
- MS-UI-PFM (NCT07489794)
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Relapsing-Remitting Multiple Sclerosis, Urinary Incontinence
Guided Versus Non-guided Pelvic Floor Exercises for Urinary Incontinence in Relapsing-Remitting Multiple Sclerosis
The aim of the study is to evaluate the effectiveness of guided versus non guided pelvic floor exercises for urinary incontinence in patients with Relapsing-Remitting Multiple Sclerosis
- Trial name
- NCT03000647
- Testing
- Pelvic floor exercises guided by a physiotherapist, Non guided pelvic floor exercises
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Tuberous Sclerosis Complex (TSC)
Observational, Retrospective, Multicenter, Nonprofit Study on the Prevalence of Renal Involvement in Pediatric Patients With Tuberous Sclerosis
Observational, retrospective, multicenter, nonprofit study on the prevalence of renal involvement in pediatric patients with tuberous sclerosis.
- Trial name
- NCT06764602
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis
Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction
A multi-center double-blinded placebo-controlled randomized clinical trial. The patients will be randomized into two groups. To investigate the efficacy of SNM to improve the key bladder diary variables compared to placebo (i.e.
- Conditions
- Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis, Sacral Neuromodulation, Bowel Dysfunction
- Trial name
- NCT05380856
- Testing
- Turning ON the neuromodulator, Turning OFF the neuromodulator
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital