Clinical trials: Workflow, open to volunteers
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Complete Edentulism
Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial
This prospective randomized crossover clinical trial evaluates and compares the clinical performance and oral health-related quality of life (OHRQoL) of complete dentures fabricated through two additive manufacturing workflows …
- Trial name
- PRINT-DENT (NCT07626827)
- Testing
- Digital Workflow Complete Denture, Hybrid Workflow Complete Denture
- Where
- Ecuador
- Volunteers
- 20 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Liver Cancer, Intrahepatic Cholangiocarcinoma
REGULUS: MRI-guided Adaptive SABR for Liver Cancers
Single arm unblinded study of simulation-free MRI-guided SABR with adaptive replanning in one session for treatment of patients with liver cancers
- Conditions
- Liver Cancer, Intrahepatic Cholangiocarcinoma, Liver Metastases, HCC
- Trial name
- NCT07223307
- Testing
- MRI-guided adaptive stereotactic ablative body radiotherapy (SABR)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation
Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial Fibrillation
The NEXT PULSE study is a pre-market, prospective, multi-center, non-randomized, interventional clinical study. Adult subjects with symptomatic paroxysmal or persistent AF who provided consent will be enrolled and treated with…
- Trial name
- NEXT PULSE (NCT07575828)
- Testing
- PulseSelect Pulse Field Ablation (PFA) System
- Volunteers
- 320 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Cognitive Load and Task Performance in Rotating Residents
Effect of a Localized ICU AI Teaching Agent on Rotating ICU Residents
This trial is an ongoing single-center, pragmatic, parallel-group randomized controlled superiority trial currently in participant recruiting phase, conducted within intensive care unit teaching wards at Peking Union Medical…
- Trial name
- NCT07692035
- Testing
- ICU-Tutor AI Agent, General-Purpose Large Language Models
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Complete Edentulism
Comparative Study of Denture Fabrication Techniques
This study is a randomized, single-blinded clinical study conducted in the predoctoral clinic at Rutgers School of Dental Medicine.
- Trial name
- NCT07525011
- Testing
- Traditional Complete Denture Fabrication, Easdent Digital Complete Denture Fabrication
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Quality Improvement, Appointments and Schedules
Enhancing Operational Efficiency in Eye Care Services
Pushpagiri Vitreo Retina Institute (PVRI) based in Secunderabad is a tertiary care eye hospital providing specialty eye care services since 2007.
- Conditions
- Quality Improvement, Appointments and Schedules, Operations Research Workflow
- Trial name
- NCT07416864
- Testing
- Health service Optimization
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Seva Canada Society
Dental Implants, Single Tooth Lost
5-year Follow up Study on the Comparative Performance of Two-piece Zirconia and Titanium Implants
A post-market, randomized-controlled, superiority clinical study to compare medium-term performance and safety of the Straumann PURE 2-piece Ceramic Implant with Straumann Bone Level Implant using a fully digital workflow.
- Conditions
- Dental Implants, Single Tooth Lost, Dental Implant Failed
- Trial name
- PostNCT0390817 (NCT05326880)
- Testing
- Ceramic Dental Implant, Titanium Dental Implant
- Where
- 2 sites in Germany, Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Patient Centered Care, Integration in Clinical Workflows
Evaluating the Effectiveness of an AI-powered Physician Assistant in Improving Patients' and Physician's Satisfaction in an Outpatient Setting of a Tertiary Care Hospital.
Patients' satisfaction depends on several factors, including health care costs, access to care, and the waiting time to see a healthcare professional.
- Trial name
- NCT07756632
- Testing
- AI Physician Assistant
- Where
- Pakistan
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Length of Stay, Emergency Department Crowding
Digital Anticipatory Protocols at Triage to Improve ED Flow.
This study aims to evaluate a pre-post intervention adding an early management decision at the end of the triage process to improve patient throughput.
- Conditions
- Length of Stay, Emergency Department Crowding, Emergency Department Patient, Emergency Department Triage
- Trial name
- NCT07726108
- Testing
- Digital Anticipatory Protocols at Triage
- Where
- Switzerland
- Volunteers
- 15,500 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Tachycardia
Molecular Autopsy in Young Individuals With Sudden Cardiac Death
The goal of this observational study is to create and test a pilot workflow for molecular autopsy (genetic testing after death) in children and adults aged 1 to 50 years who died suddenly from an unexplained cause and were…
- Trial name
- NCT07849738
- Testing
- Molecular autopsy by whole exome sequencing, Cascade genetic screening by targeted Sanger sequencing
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Prostate Cancer, Prostatic Neoplasm
Investigation of Impact of AI on Prostate Cancer Workflow
This study will enroll participants who are undergoing an MRI before a prostate biopsy due to suspected prostate cancer. The purpose of this study is to see if the use of Artificial Intelligence (AI) helps detect lesions on an…
- Conditions
- Prostate Cancer, Prostatic Neoplasm, Cancer of the Prostate, Neoplasms, Prostate
- Trial name
- NCT07084779
- Testing
- AI
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Case Comprehensive Cancer Center
Quality of Care, Patient Satisfaction
Evaluating the Effectiveness of an AI-Powered Physician Assistant in Improving Patients' and Physicians' Satisfaction in Anaesthesiology Clinics
This trial aimed to evaluate the effectiveness of an AI-Powered Physician Assistant in improving patients' satisfaction with the quality of care.
- Conditions
- Quality of Care, Patient Satisfaction, Physician Satisfaction
- Trial name
- NCT07743320
- Testing
- AI-Powered Physicians' Assistant
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
TMD
AMOUNT OF INTRAORAL OCCLUSAL ADJUSTMENTS IN OCCLUSAL SPLINTS FABRICATED USING FULLY DIGITAL VERSUS COMBINED DIGITAL WORKFLOW IN TMD PATIENTS
Each eligible patient will be randomly into one of two groups: group A: Occlusal splints fabricated using a fully digital workflow including the use of a jaw tracking device.
- Trial name
- NCT06752200
- Testing
- Occlusal splints fabricated using a fully digital workflow including the use of a jaw tracking device., Occlusal splints fabricated using a combined digital workflow using a conventional bite technique
- Volunteers
- 26 people
- Sponsor
- Cairo University
Patient Safety
Evaluating a Fingerprint System to Improve Patient Identification in Cardiac Surgery
The purpose of this prospective observational pilot study is to evaluate the usability, workflow integration, and operational feasibility of a fingerprint-based patient identification system (the Heuristik system) within…
- Trial name
- NCT07846644
- Testing
- Heuristik Fingerprint Identification System
- Volunteers
- 65 people
- Sponsor
- Heuristik Technologies SL
Pain Management, Injection Pain Prevention
Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic
The goal of this clinical trial is to learn whether virtual reality (VR) can be added to routine knee injection appointments at a VA outpatient pain clinic without slowing down or disrupting clinic operations.
- Conditions
- Pain Management, Injection Pain Prevention, Virtual Reality, Feasibility Studies
- Trial name
- NCT07884851
- Testing
- Immersive Virtual Reality
- Volunteers
- 45 people
- Sponsor
- Atlanta VA Medical Center
Hip Prosthesis
Modeling and Workflow Recognition for the Anterior Approach in Total Hip Arthroplasty
The purpose of this study is to create a systematic and general description of the surgical process for the direct anterior approach (DAA) in total hip arthroplasty (THA).
- Trial name
- NCT05993845
- Testing
- Recording of total hip arthroplasty
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Philipp Fürnstahl
Transverse Maxillary Deficiency
Digital vs. Analog Inputs in CAD/CAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow
36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD/CAM…
- Trial name
- NCT07338591
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University