Clinical trials: Workflow, active
Alzheimer Disease, Dementia
Novel Neuroradiological Workflow for the Assisted DIAgnosis and Management of DEMentia with Artificial Intelligence
Identifying, screening and monitoring individuals at risk of Alzheimer's disease (AD) and dementia is a formidable challenge. Neuroimaging, and in particular magnetic resonance imaging (MRI), is crucial to detect structural…
- Trial name
- DIADEMA (NCT06877182)
- Testing
- Magnetic Resonance Imaging with Contrast
- Where
- Italy
- Volunteers
- 80,000 people
- Sponsor
- IRCCS SYNLAB SDN
Radiology, Medical Errors
AI-Based Quality Control for Radiology Reporting
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-based radiology report quality-control system can improve the accuracy and workflow efficiency of routine radiology reporting among active…
- Trial name
- NCT07865741
- Testing
- Radiology Report GPT (AI-Based Radiology Report Quality-Control System)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
High-Grade Glioma (WHO III-IV), Cerebral Vascular Conditions Requiring Surgical Intervention
Evaluation of Image Quality and Safety of the MyVeo Surgical Visualization Headset During Standard Neurosurgical and Reconstructive Procedures Using Compatible Microscopes.
This study looks at how well the MyVeo surgical visualization headset works during routine surgeries. MyVeo is a wearable device that helps surgeons see the surgical area in high detail, including blood flow and tissue…
- Conditions
- High-Grade Glioma (WHO III-IV), Cerebral Vascular Conditions Requiring Surgical Intervention, Conditions Requiring Plastic and Reconstructive Surgery
- Trial name
- IMED-MYVEO (NCT07164053)
- Testing
- MyVeo is an all-in-one surgical visualization headset used with compatible surgical microscopes and other medical imaging systems in the area of neurosurgery, ENT, spine, plastic and reconstructive su
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 32 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Clostridioides Difficile Infection, Healthcare Associated Infection
Evaluation of GeoHAI Implementation
Geographic Information Systems (GIS) and spatial analysis have become important tools in public health informatics but have rarely been applied to the hospital setting.
- Trial name
- NCT05612672
- Testing
- GeoHAI
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Liver Cancer, Intrahepatic Cholangiocarcinoma
REGULUS: MRI-guided Adaptive SABR for Liver Cancers
Single arm unblinded study of simulation-free MRI-guided SABR with adaptive replanning in one session for treatment of patients with liver cancers
- Conditions
- Liver Cancer, Intrahepatic Cholangiocarcinoma, Liver Metastases, HCC
- Trial name
- NCT07223307
- Testing
- MRI-guided adaptive stereotactic ablative body radiotherapy (SABR)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Posterior Single Edentulous Sites
Monolithic Zirconia Posterior Single Crowns: a Randomized Clinical Trial.
Monolithic Zirconia Posterior Single Crown cost-efficiency study. Objective and subjective analysis will be performed through FIPS and PROMs scales to evaluate treatment quality outcomes.
- Trial name
- NCT06865209
- Testing
- Monolithic Zirconia Posterior Single Screw Retained Implant Crowns
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Reconstructive Surgical Procedures, Plastic Surgery
Leica Microsystems Sponsored Study to Collect and Confirm Clinical Data on the Performance of the GLOW800 Device When Used in Accordance With Its Intended Use.
This post-market clinical follow-up (PMCF) study aims to confirm the safety and performance of the GLOW800 surgical microscope accessory when used in conjunction with the ARveo8x surgical microscope.
- Conditions
- Reconstructive Surgical Procedures, Plastic Surgery, Vascular Surgical Procedure, Cerebrovascular Disorder
- Trial name
- IMED-GLOW800 (NCT07164040)
- Testing
- The GLOW800, a non-contact, non-invasive device, allows the surgical microscope ARveo 8 and ARveo 8X to produce excitation light and resolve fluorescence emission from the fluorescent agent ICG
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 29 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Cognitive Load and Task Performance in Rotating Residents
Effect of a Localized ICU AI Teaching Agent on Rotating ICU Residents
This trial is an ongoing single-center, pragmatic, parallel-group randomized controlled superiority trial currently in participant recruiting phase, conducted within intensive care unit teaching wards at Peking Union Medical…
- Trial name
- NCT07692035
- Testing
- ICU-Tutor AI Agent, General-Purpose Large Language Models
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Patient Safety
Evaluating a Fingerprint System to Improve Patient Identification in Cardiac Surgery
The purpose of this prospective observational pilot study is to evaluate the usability, workflow integration, and operational feasibility of a fingerprint-based patient identification system (the Heuristik system) within…
- Trial name
- NCT07846644
- Testing
- Heuristik Fingerprint Identification System
- Volunteers
- 65 people
- Sponsor
- Heuristik Technologies SL
Cancer
Introduction of Y90-PET-CT Post Radioembolisation Therapy Scans
Yttrium-90, attached to microspheres, usually referred to as 90Y-microspheres or Y-90 radioembolisation, can be used in some cases to treat patients with liver tumours or liver metastasis.
- Trial name
- Y90-PET-CT (NCT06123676)
- Testing
- Y90-PET-CT scan
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- The Christie NHS Foundation Trust
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Transverse Maxillary Deficiency
Digital vs. Analog Inputs in CAD/CAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow
36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD/CAM…
- Trial name
- NCT07338591
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Clinical Deterioration
Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-Pediatric
The purpose of this study is to evaluate the effectiveness and user satisfaction of the study teams early warning system, called PICTURE, which utilizes artificial intelligence (AI) techniques and algorithms to identify patient…
- Trial name
- NCT07304050
- Testing
- PICTURE-Pediatric scores and alerts, Control Arm - Scores and alerts hidden
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- University of Michigan
Tachycardia
Molecular Autopsy in Young Individuals With Sudden Cardiac Death
The goal of this observational study is to create and test a pilot workflow for molecular autopsy (genetic testing after death) in children and adults aged 1 to 50 years who died suddenly from an unexplained cause and were…
- Trial name
- NCT07849738
- Testing
- Molecular autopsy by whole exome sequencing, Cascade genetic screening by targeted Sanger sequencing
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Quality Improvement, Appointments and Schedules
Enhancing Operational Efficiency in Eye Care Services
Pushpagiri Vitreo Retina Institute (PVRI) based in Secunderabad is a tertiary care eye hospital providing specialty eye care services since 2007.
- Conditions
- Quality Improvement, Appointments and Schedules, Operations Research Workflow
- Trial name
- NCT07416864
- Testing
- Health service Optimization
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Seva Canada Society
Stroke, Acute
WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)
The WE-TRUST study is a multi-center randomized clinical trial to assess the impact of a Direct to Angio Suite (DTAS) workflow on stroke patient outcomes.
- Trial name
- NCT04701684
- Testing
- Direct to Angio Suite (DTAS) Philips' CBCT triage, Conventional CT/MR triage
- Where
- 24 sites in United States, Argentina and 8 more
- Volunteers
- 594 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Digital Intervention
Complete Digital Workflow
This study will aim to clinical evaluation of titanium-zirconium and peek-composite of screw retained prosthesis used for rehabilitation of edentulous patients using Complete digital workflow for construction of full arch implant…
- Trial name
- NCT07091786
- Testing
- Implant supported prosthesis
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Physician Workflow, Resource Utilization
Evaluating a Our Practice Advisory (OPA) to Optimize Hemoglobin A1c (A1c) and Thyroid-Stimulating Hormone (TSH) Test Orders
Our Practice Advisory (OPA) are essential tools in clinical decision-making. The alerts are designed to guide providers towards evidence-based practices and improve patient outcomes.
- Trial name
- NCT06993805
- Testing
- OPA
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- University of California, Los Angeles
Complete Edentulism
Comparative Study of Denture Fabrication Techniques
This study is a randomized, single-blinded clinical study conducted in the predoctoral clinic at Rutgers School of Dental Medicine.
- Trial name
- NCT07525011
- Testing
- Traditional Complete Denture Fabrication, Easdent Digital Complete Denture Fabrication
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Clinical Decision Support Systems, Diagnostic Reasoning
Effects of Agent-assisted, LLM-assisted and Traditional Workflows on Diagnosis and Management Planning at Admission
The goal of this clinical trial is to evaluate whether AI-assisted workflows improve physicians' admission diagnosis and management planning performance on standardized simulated inpatient cases, among practicing internal…
- Conditions
- Clinical Decision Support Systems, Diagnostic Reasoning, Artificial Intelligence (AI)
- Trial name
- NCT07760051
- Testing
- Agent-assisted workflow, LLM-assisted workflow, Traditional Workflow
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine