Clinical trials: Worry, open to volunteers
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
ERP to Improve Functioning in Veterans With OCD
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no…
- Trial name
- NCT05240924
- Testing
- Exposure and Response Prevention, Stress Management Training
- Where
- 19 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Clinical Comfort and Worry, Readiness Levels for Clinical Practice
The Effect of the Excellence Model-Based Clinical Practice Preparation Program on Students
Objective: This study was designed to develop a clinical practice preparation program based on the Pediatric Nursing Excellence Model for undergraduate nursing students and to evaluate the program's effect on students' readiness…
- Conditions
- Clinical Comfort and Worry, Readiness Levels for Clinical Practice, Pediatric Nursing Excellence Level, Nursing Student
- Trial name
- NCT07405580
- Testing
- Educational intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Anxiety, Anxiety Depression
Calming Minds Study
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1.
- Conditions
- Anxiety, Anxiety Depression, Worry, Depression
- Trial name
- NCT07577401
- Testing
- Be Specific, Be Kind, Be Present
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, Los Angeles
Distress, Emotional, Emotional Dysfunction
Brief Interventions for Coping with Distress
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training…
- Conditions
- Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
- Trial name
- NCT05779761
- Testing
- Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Teachers College, Columbia University
Generalized Anxiety Disorder
Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a serious and long-lasting condition that can greatly reduce quality of life, work functioning, and use of health services.
- Trial name
- NCT07579897
- Testing
- Individual Metacognitive Therapy, Group Metacognitive Therapy
- Where
- 2 sites in Norway
- Volunteers
- 64 people
- Sponsor
- Sorlandet Hospital HF
Generalized Anxiety Disorder (GAD)
Transcranial Alternating Current Stimulation to Enhance Mindfulness Therapy in Generalized Anxiety Disorder
This randomized, double-blind, sham-controlled clinical trial will evaluate whether individualized alpha-frequency transcranial alternating current stimulation (tACS) can enhance the effects of mindfulness therapy in adults with…
- Trial name
- NCT07648797
- Testing
- Synchronous Individualized Alpha-Frequency tACS, Desynchronous Individualized Alpha-Frequency tACS, Mindfulness Therapy
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Central South University
Dementia, Alzheimer Disease
Integrating eSAGE With EHR Data Using Machine Learning for the Early Detection and Monitoring of Cognitive Impairment in Individuals
The goal of this observational trial is to leverage the electronic Self-Administered Gerocognitive Examination (eSAGE), a variety of metadata (a set of data that describes and gives information about other data) collected during…
- Conditions
- Dementia, Alzheimer Disease, Mild Cognitive Impairment, Worried Well
- Trial name
- NCT06017505
- Testing
- electronic self administered gerocognitive examination (eSAGE)
- Where
- United States
- Volunteers
- 1,486 people
- Sponsor
- Douglas Scharre
Active tDCS, Sham tDCS
Combination of Neurostimulation and Psychotherapy to Stop Worrying
This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with…
- Trial name
- NCT06369532
- Testing
- Active tDCS
- Where
- Belgium
- Volunteers
- 85 people
- Sponsor
- University Hospital, Ghent
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Patients
Patient Worries Previous to Dental Treatment
This is a multicenter cross-sectional study that aims to provide a snapshot of the experience of patients before starting dental treatment.
- Trial name
- NCT06396442
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Aula Dental Avanzada
Depression, Anxiety
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder, Stress
- Trial name
- Blueprint 2 (NCT06538246)
- Testing
- Blueprint, Education program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Duke University
Insomnia, Depression
Sleep to Reduce Incident Depression Effectively in Peripartum
Perinatal depression (PND) is the most common complication in pregnancy and postpartum, which increases risk for adverse perinatal outcomes such as preterm birth, maternal suicidal thoughts, and impaired mother-infant bonding.
- Trial name
- STRIDE P (NCT06430333)
- Testing
- Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Henry Ford Health System
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer
The goal of the study is: The collection of various tissue samples (blood, biopsies and "esophageal brushes") and their analysis.
- Conditions
- Barrett Esophagus, Barrett Esophagus Adenocarcinoma, Adenocarcinoma - GEJ, Gastroenterology
- Trial name
- Endeavor-2 (NCT07455422)
- Testing
- Risk profile disclosure
- Where
- 10 sites in Belgium, Denmark and 5 more
- Volunteers
- 266 people
- Sponsor
- University Hospital, Antwerp
Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL), Marginal Zone Lymphoma(MZL)
Watch and Wait or Worry and Wait in Indolent Lymphoma
Indolent lymphomas, including chronic lymphocytic leukemia/small lymphocytic lymphoma, marginal zone lymphoma, low-grade follicular lymphoma, and Waldenström macroglobulinemia, are slow-growing cancers often managed initially…
- Conditions
- Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL), Marginal Zone Lymphoma(MZL), Follicular Lymphoma, Grade 1, Follicular Lymphoma, Grade 2
- Trial name
- NCT07173790
- Testing
- Patient-Reported Outcomes Survey
- Where
- 4 sites in South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
Rumination, Worry
Readiness and Progress in Emotion Regulation Therapy
This study is an open trial designed to examine individual changes that occur before, during, and after 6 modules of Emotion Regulation Therapy (ERT) delivered via telehealth for individuals in New York State who are experiencing…
- Conditions
- Rumination, Worry, Self-Criticism, Anxiety
- Trial name
- NCT07478393
- Testing
- Emotion Regulation Therapy via Telehealth
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Teachers College, Columbia University
Pregnancy Trimester, First, Anxiety
Addressing Pregnant Women's First Trimester Worries and Information Needs With mHealth Solutions
The first 12 weeks of pregnancy, known as the first trimester, can be one of the most worrying times for women. (Where this lay summary refers to women, it should be taken to include people who do not identify as women but who…
- Conditions
- Pregnancy Trimester, First, Anxiety, Worries, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07114471
- Where
- United Kingdom
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Generalized Anxiety, Anger
Experiences of Anger in Patients in Primary Health Care With Symptoms of Generalized Anxiety
Symptoms of generalized anxiety is common in the general population and is often treated in primary health care. Anger is an emotion that can lead to interpersonal problems but can also be an agent for justice and change.
- Conditions
- Generalized Anxiety, Anger, Primary Health Care
- Trial name
- NCT04702711
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Kronoberg County Council
Patient Education, Surgical Fear and Worrying
The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress
Gallbladder stone disease is among the most common digestive system problems worldwide. The global incidence of gallstones is estimated to be 10-20%. In Europe, this rate is approximately 20%.
- Conditions
- Patient Education, Surgical Fear and Worrying, Surgical Stress Response, Medical-surgical Nursing
- Trial name
- NCT07100275
- Testing
- Patient education, Follow-up via Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bingol University