Clinical trials: Wound; Knee
Anterior Cruciate Ligament Rupture
Femoral Tunnel Position on Conventional MRI After Anterior Cruciate Ligament Reconstruction-Transtibial Technique Versus Transportal Technique
The position of the femoral tunnel in anterior cruciate ligament (ACL) reconstruction has been assessed on three dimensional CT (3D-CT) scan or in cadaveric study.
- Trial name
- NCT01513434
- Testing
- transtibial technique, Transportal technique, anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- National Police Hospital
Tibial Plateau Fractures
EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES
This study will answer the following research questions: Are there any significant differences between combination of early active knee ROM exercises and weight bearing versus early passive ROM with delayed weight bearing on pain…
- Trial name
- NCT07251699
- Testing
- Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lower Limb Amputation Above Knee (Injury)
Progressive Muscle Relaxation Technique on Lower Limb Amputation
To determine the effects of progressive muscle relaxation technique on pulmonary functions in lower limb amputation patients. Randomized control Trail study design was chosen for this study, sampling technique Non probability…
- Trial name
- NCT04051164
- Testing
- Progressive Muscle Relaxation Technique, Conventional treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Recurrent Patellar Dislocation, Osteotomy
The Clinical Results of Derotational Osteotomy Based on 3D Osteotomy Template for Treatment of Recurrent Patellar Dislocation Combined With Patellofemoral Maltracking
For severe recurrent patellar dislocation with poor patellar maltracking, derotation osteotomy is an effective clinical treatment. However, derotation osteotomy requires very high requirements for the surgeon.
- Conditions
- Recurrent Patellar Dislocation, Osteotomy, Patellar Maltracking
- Trial name
- NCT04556799
- Testing
- computer-assisted surgery, traditional osteotomy
- Volunteers
- 50 people
- Sponsor
- Beijing Jishuitan Hospital
Wound Closure
Symmetric on Total Knee Arthroplasty (TKA)
A post-marketing prospective, multicenter, randomized controlled study to evaluate the wound closure efficiency of STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device (STRATAFIX Symmetric PDS Plus) compared to…
- Trial name
- SFX (NCT03305887)
- Testing
- "STRATAFIX™ Symmetric" Knotless Tissue, VICRYL® PLUS, "STRATAFIX Spiral" sutures
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- Johnson & Johnson Medical, China
Lower Limb Amputation Above Knee (Injury)
Analyzing Stump-socket Interface Pressure to Improve Gait in Above-knee Amputee
This study aims at evaluating the relation between quality of the interface between the stump and the prosthesis, and the quality of gait in above-knee amputees.
- Trial name
- NCT01848964
- Testing
- Clinical and instrumented measurements
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
ACL Injury
Andrews Return to Sport ACL Score
This project will develop a data-driven decision making model to assess a competitive athlete's readiness to return to sport after ACL injury and surgery safely.
- Trial name
- NCT05578248
- Testing
- Magnetic Resonance Imaging (MRI), ACL reconstruction
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Andrews Research & Education Foundation
Arthroplasty, Replacement
Effect of Dexmedetomidine on Ischemia-Reperfusion Injury in Lower Extremity Operations
Ischemia reperfusion injury causes the release of free oxygen radicals. The selective alpha2-receptor agonist, dexmedetomidine, has an inhibitory effect on inflammatory responses during ischemic injury.
- Trial name
- NCT02648958
- Testing
- Dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Yonsei University
Knee Injuries, Knee Osteoarthritis
Blood-Flow Restriction Exercise Following a Knee Replacement
This study will determine the safety and efficacy of using blood-flow restriction exercise enhancement (B-FREE) to overcome persistent quadriceps muscle weakness that occurs following a total knee replacement (TKR).
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04018638
- Testing
- B-FREE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University
Sedentary Lifestyle, Knee Osteoarthritis
NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries
This study will evaluate the effectiveness of an mHealth sedentary reduction program over a 6-month period of time in adults with past or present knee symptoms, injuries, or surgeries.
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT03987932
- Testing
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Knee Injuries
Electrostimulation in Anterior Cruciate Ligament Reconstruction
The anterior cruciate ligament (ACL) is frequently injured, and it is the structure of the athlete´s knee which has the highest prevalence of reconstruction.
- Trial name
- NCT01633047
- Testing
- electrical stimulation, physical therapy exercises
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
ACL, ACL - Anterior Cruciate Ligament Rupture
Conservative Treatment With Blood Flow Restriction in Patients With Total ACL Rupture. "Randomized Clinical Trial"
The goal of this randomised clinical trial is to evaluate the effects of exercise with blood flow restriction (BFR) in patients with a complete anterior cruciate ligament (ACL) rupture.
- Trial name
- NCT06727344
- Testing
- Blood Flow Restriction, Brace
- Where
- 2 sites in Cyprus
- Volunteers
- 20 people
- Sponsor
- European University Cyprus
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament Tear, Pain, Postoperative
Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction
This is a prospective, randomized study for adult patients presenting to the Carilion Clinic Institute of Orthopedics and Neurosurgery. Patients undergoing isolated ACL reconstruction will be eligible for inclusion.
- Conditions
- Anterior Cruciate Ligament Tear, Pain, Postoperative, Opioid Use
- Trial name
- NCT04764916
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Knee Injuries
Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
In this randomized controlled trial the investigators will compare the results after primary anterior cruciate ligament (ACL) reconstruction using two different methods for femoral fixation of a bone-patellar tendon-bone (BPTB)…
- Trial name
- NCT02918734
- Testing
- Endobutton CL BTB, Metal interference screw
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Knee Injuries
New MRI Measurement of Patellar Height in Knee Extension - IES-EV Control Study
The measurement of the patellar height is essential to decide and quantify the surgical correction to be made. The classic index is that of Cato and Deschamps.
- Trial name
- NCT05659316
- Testing
- MRI imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Knee
Reverse Innovation in Western Health Care: the ReMotion Prosthetic Knee.
Ambulatory mobility and function are important aspects in the quality of life of people with lower limb amputations and prostheses.
- Trial name
- NCT04700085
- Testing
- ReMotion Knee
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- Sint Maartenskliniek
Lower Limb Amputation Above Knee (Injury)
Assessment of the Prosthetic System Impact on Mental Workload in Above-knee Lower Limb Amputees.
New generation of lower limb prosthesis provide improved functionalities. They are usually studied in the scope of biomechanics, sometimes PROMs like quality of life.
- Trial name
- INCREMENT (NCT06635655)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Proteor Group
Anterior Cruciate Ligament Injury
Natural Course and Recovery After ACL-injury
The natural course after ACL injury is not well described in the literature. Every year about 7000 people, a majority aged 15-30 years old, injure their anterior cruciate ligament (ACL) in Sweden.
- Trial name
- NACOX (NCT02931084)
- Testing
- Rehabilitation, ACL reconstruction
- Where
- Sweden
- Volunteers
- 275 people
- Sponsor
- Linkoeping University
Sprain, Strain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment of acute musculoskeletal pain.
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Trial name
- NCT00765700
- Testing
- Topical Ketoprofen 10% Cream
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Imprimis Pharmaceuticals, Inc.
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