Clinical trials: Wound; Knee
Anterior Cruciate Ligament Injuries
Reverse Drilling Technique in Improving Outcomes After Arthroscopic Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injuries and bone tunnel enlargement (BTE) after ACL reconstruction (ACLR) remain frequent issues.
- Trial name
- NCT05994872
- Testing
- Reverse drilling technique, Traditional extraction drilling
- Where
- 6 sites in China
- Volunteers
- 216 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Recurrent Patellar Dislocation, Patellar Instability
Evaluation of Adductor Magnus Tenodesis in Patients With Recurrent Patellar Dislocation.
Between 2010 and 2012, 33 children and adolescents (39 knees) with recurrent patellar dislocation were treated with MPFL reconstruction using the adductor magnus tendon.The aim of the study is to assess the effectiveness of this…
- Conditions
- Recurrent Patellar Dislocation, Patellar Instability, Patellofemoral Osteoarthritis
- Trial name
- NCT05184439
- Testing
- Adductor magnus tenodesis for recurrent patellar dislocation
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Sport Injury, Sports Physical Therapy
Prediction of Knee Injuries Through System Dynamics Modeling
The large number of studies in the recent decade dealing with knee injury prevention seems not effective enough to cause a decline in knee injury rates.
- Trial name
- NCT05430581
- Where
- Greece
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Patras
Anterior Cruciate Ligament Tear, Meniscal Tear
Prospective Registry of Anterior Cruciate Ligament Reconstructions
The purpose of the study is to investigate factors that are associated with outcomes of injury to the anterior cruciate ligament (ACL) in the knee among patients who are undergoing surgical reconstruction.
- Conditions
- Anterior Cruciate Ligament Tear, Meniscal Tear, Cartilage Injury, Bone Bruising
- Trial name
- NCT04135950
- Where
- United States
- Volunteers
- 1,646 people
- Sponsor
- State University of New York at Buffalo
Post-Traumatic Osteoarthritis of Knee, Knee Injuries
Changes in the Immunomodulatory Properties of Adipose Stromal Cells Due to Hemarthrosis After Knee Injury
The goal of this observational study is to gain insight in the natural course of pro-inflammatory factors and hemarthrosis in patients older than 18 with a recent knee trauma.
- Conditions
- Post-Traumatic Osteoarthritis of Knee, Knee Injuries, Hemarthrosis
- Trial name
- CASH (NCT05687331)
- Testing
- knee arthrocentesis, venipuncture, MRI-scan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cartilage Injury, Osteoarthritis
Study to Compare Efficacy and Safety of Cartistem and Microfracture in Patients With Knee Articular Cartilage Injury
The purpose of the study is to assess and compare the safety and efficacy of the allogeneic-unrelated umbilical cord blood-derived mesenchymal stem cell product (Cartistem®) to that of a microfracture treatment in patients with…
- Trial name
- NCT01041001
- Testing
- Cartistem, Microfracture treatment
- Where
- 8 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Medipost Co Ltd.
Muscle Atrophy, Surgery
Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study
The loss of muscle mass post-surgery confounds recovery efforts and leads to a delay in patient's ability to return to activities.
- Conditions
- Muscle Atrophy, Surgery, Knee Injuries and Disorders, Complication of Surgical Procedure
- Trial name
- NCT04456530
- Testing
- Aveed 750 MG in 3 ML IM Injection, Normal Saline 3 ML IM Injection
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Stone Research Foundation for Sports Medicine and Arthritis
ACL Injury
Causes and Patterns of Anterior Cruciate Ligament Injuries Among Egyptian Population
The aim of work is to detect the patterns and the causes of ACL injury among Egyptian population and to identify its risk factors. Identify the male to female ratio of injuries in our community.
- Trial name
- NCT03773341
- Testing
- research questionnaire
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arthroplasty, Knee Replacement, Wound Healing
Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty
Study designed to compare the Zip Surgical Skin Closure device vs. conventional staples for wound closure following bi lateral knee replacement surgery.
- Trial name
- NCT02460172
- Testing
- Zip Surgical Skin Closure, Steel Staples
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZipLine Medical Inc.
Arthroplasty, Replacement, Knee, Acute Kidney Injury
Kidney Biomarkers of Acute Kidney Injury in Patients With Knee Arthroplasty
Sensitive renal markers have been studied abundantly in connection with open heart, liver and transplantation surgery; however in major orthopaedic surgery their use is anecdotal.
- Trial name
- dexpolvi (NCT02642731)
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Kuopio University Hospital
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Knee Injuries, Shoulder Injuries
Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
The investigators have previously reported on patient utilization of an eRehab patient education web portal that utilizes streaming, clinician prescribed video instruction to motivate and inform patients in self-care of their…
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear
- Trial name
- NCT02025400
- Testing
- eRehab, Formal Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charlotte Sports Medicine Institute, PA
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury
The purpose of this study is to assess if a zoledronic acid injection can alter the trajectory of joint degeneration following an acute anterior cruciate ligament (ACL) injury.
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis Knee
- Trial name
- ZAPOA (NCT05204836)
- Testing
- Zoledronic Acid Injection
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Calgary
Patellar Instability
Comparison of Dynamic and Static Medial Patellofemoral Ligament Operation Technique for Recurrent Patellar Dislocation
This study is to evaluate whether the dynamic Medial Patellofemoral Ligament (MPFL) reconstruction as described by Becher is a successful operation technique to prevent patella instability and restore quality of life.
- Trial name
- DynMPFL (NCT04849130)
- Testing
- Static reconstruction technique according to Schöttle, Dynamic reconstruction technique according to Becher
- Where
- 2 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Anterior Cruciate Ligament Rupture
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different, 2.
- Trial name
- NCT06769711
- Testing
- Surgical procedure using Peroneus Longus for ACL reconstruction., Surgical procedure using Hamstring tendons for ACL reconstruction.
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Karadeniz Technical University
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Benchmarking the iOS Balance Application Against the Berg Balance Test
This study aims to benchmark the performance of an iOS application against the Berg Balance Scale (BBS), which is the most commonly used assessment tool by clinicians for measuring balance across the continuum from acute care to…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Ankle Injuries, Knee Injuries
- Trial name
- BBAaBBT (NCT02705690)
- Testing
- iOS Balance Application
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stannah Stairlifts
ACL Injury
Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture
Anterior knee pain which might be due to patellofemoral malalignment is an inevitable post operative complication after an ACL reconstruction (ACLR).
- Trial name
- NCT06004297
- Testing
- ACL reconstruction
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
Injury
Stories to Educate Patients With Ankle, Foot, and Knee Injuries
Study will test the use of narratives on patient satisfaction and translation of an evidence-based approach to the use of X-rays for leg injuries in the Emergency Department (ED).
- Trial name
- NCT01810523
- Testing
- Narrative, Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Anterior Cruciate Ligament Reconstruction, Knee Injury
Quadriceps and Hamstring Activation Timing
The anterior cruciate ligament (ACL) plays a crucial role in maintaining knee stability and enabling dynamic movement. ACL injuries are common, especially among athletes, and reconstruction surgery is frequently performed to…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Knee Injury, Neuromuscular Control
- Trial name
- NCT07532980
- Testing
- Electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- KTO Karatay University
Injury of Foot, Shoulder or Knee, Perineural Analgesia
Postoperative Patient-controlled Perineural Analgesia After Orthopedic Surgery by "Remote Control" Versus "Bedside Care"
Perineural injection of local anesthesic is currently the reference method for the treatment of post operative pain in a patient undergoing major orthopedic surgery. Postoperative pain is a dynamic phenomena in every patient.
- Conditions
- Injury of Foot, Shoulder or Knee, Perineural Analgesia, Pain, Postoperative
- Trial name
- MICREL (NCT02018068)
- Testing
- Remote control, At bedside care
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
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