Clinical trials: Wound; Knee
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University
Knee Injury
Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.
Determine the ability of the allograft plug for the treatment of a cartilage injury in the knee
- Trial name
- NCT00793104
- Testing
- Placement of allograft CR Plug in primary injury site
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- RTI Surgical
Anterior Cruciate Ligament Injury, Quadriceps Dysfunction
Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
FROM RISK FACTORS TO THE PREVENTION OF LONG-TERM CONSEQUENCES AFTER CRUCIATE LIGAMENT INJURY (ACL injury) - This is a research project where we seek new knowledge about why some people have a high risk and others a low risk of…
- Conditions
- Anterior Cruciate Ligament Injury, Quadriceps Dysfunction, Knee Joint Loading, Anterior Cruciate Ligament Reconstruction
- Trial name
- ExeLoadBioPTOA (NCT06892899)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- May Arna Risberg
Knee Injuries and Disorders, Ankle Injuries and Disorders
Prevention of Musculoskeletal Injuries in Slovenian Armed Forces
Physical readiness of military personnel is a cornerstone of any army, as soldiers are expected to meet high physical demands on a daily basis, and soldiers must complete one hour of physical conditioning each day.
- Conditions
- Knee Injuries and Disorders, Ankle Injuries and Disorders, Low Back Pain
- Trial name
- NCT03415464
- Testing
- Exercise
- Where
- Slovenia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Wound Infection
Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement
Total knee replacement is now one of the most popular reconstructive procedures for the elderly people to regain their functional capacity and life quality.
- Trial name
- Vicryl-Plus (NCT02533492)
- Testing
- vicryl, Vicryl plus
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Mel Shiuann-Sheng Lee
Anterior Cruciate Ligament Rupture
Cross Bracing Protocol Versus Surgery for Acute Anterior Cruciate Ligament Rupture
The aim of the EMBRACE clinical trial is to compare outcomes (knee pain, symptoms, function and quality of life) between people with anterior cruciate ligament (ACL) rupture who are managed with either a novel bracing protocol…
- Trial name
- EMBRACE (NCT06956339)
- Testing
- Early anterior cruciate ligament surgery, Novel bracing protocol
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- University of Melbourne
Musculoskeletal Pain, Knee Osteoarthritis
Impact of Mesenchymal Stem Cells in Knee Osteoarthritis
Many patients with osteoarthritis of the knee fail non-operative measures and elect to have knee arthroplasty to improve their quality of life.
- Conditions
- Musculoskeletal Pain, Knee Osteoarthritis, Cartilage Injury, Cartilage Degeneration
- Trial name
- NCT03477942
- Testing
- Autologous Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Iliotibial Band Syndrome
Effects of Myofascial Release With and Without EMMETT Technique in Iliotibial Band Syndrome
The iliotibial (IT) tract or band is a lateral thickening of the fascia lata that is composed of the distal fusion of the muscular fascia of the gluteus maximus and tensor fascia lata muscles.
- Trial name
- NCT05459623
- Testing
- Manual myofascial release, Emmett intervention
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Knee Injuries and Disorders
The Effect of Different Focusing Methods on Muscle Activity
The aim of this study is to compare the effects of different focusing methods on muscular activity
- Trial name
- NCT05185882
- Testing
- Single leg squat
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
ACL Injury
Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Currently, most patients with an anterior cruciate ligament injury undergo surgery. There is a general belief that surgical reconstruction is necessary to safely return to sports and to prevent early knee osteoarthritis or…
- Trial name
- IODA (NCT05747079)
- Testing
- Rehabilitation, Optional delayed anterior cruciate ligament reconstruction, Immediate anterior cruciate ligament reconstruction
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Collateral Ligament, Knee; Sprain (Strain), Medial, Anterior Cruciate Ligament Injuries
Medial Collateral Ligament Reconstruction With Anteromedial Reinforcement for Medial and Anteromedial Rotatory Knee Instability
The aim of this study is to assess the outcomes of the combined quadriceps tendon-bone (QTB) ACLR and MCLR with anteromedial reinforcement performed as described in the published technique: K. Malinowski, K. Hermanowicz, A.
- Trial name
- NCT05489627
- Testing
- Medial Collateral Ligament Reconstruction With Anteromedial Reinforcement
- Where
- Poland
- Volunteers
- 17 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Meniscal Injuries
Novel One-step Repair of Knee Meniscal Tear Using Platelet-rich Fibrin
Currently, most knee meniscal tears are treated by partial or complete meniscectomy, or by suture repair when it is possible. Recently, the investigators have successfully developed and implanted a novel biomaterial…
- Trial name
- NCT01211119
- Testing
- No PRF
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Taipei Medical University WanFang Hospital
Osteochondral Lesions of Knee, Osteo Arthritis
3D-Printed Grafts for Knee Cartilage Repair
Research Title:A study on 3D printing-assisted platelet-rich plasma combined with autologous periosteum-bone grafting in the treatment of knee cartilage injury Objectives:(1) To evaluate the accuracy of cartilage damage repair by…
- Trial name
- 3D-PR-PBG (NCT07312175)
- Testing
- 3D-Printed Scaffold-Assisted PRP Combined with Autologous Periosteal-Bone Grafting, 3D Printing-Assisted Autologous Periosteal-Bone Grafting
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Cartilage Injury
The Hyalex First-in-Human Study
The Hyalex First-in-Human Study is a prospective, multicenter, open-label, single-arm, 2-phase, first-in-human study to evaluate the safety and technical performance of the HYALEX Knee Cartilage System for replacement of loss of…
- Trial name
- NCT06344481
- Testing
- Surgical (Hyalex Cartilage Knee Implant)
- Where
- 2 sites in Poland
- Volunteers
- 15 people
- Sponsor
- Hyalex Orthopaedics, Inc.
Hematoma, Arthroplasty Complications
The Effect of Releasing the Tourniquet in Total Knee Replacement Before Closure on the Blood Loss , Joint Effusion , Hematoma Formation and Wound Complication
The study , observe the effect of releasing the Tourniquet in total knee replacement surgery before closure in comparison with releasing it after wound closure The effect was assessed by Hb drop post operative and Hematoma…
- Trial name
- NCT04810000
- Testing
- tourniquet
- Where
- Jordan
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Yazan Saleh Rajab Hammad
Infection, Surgical Site Infection
Changing of Dressing for Periprosthetic Joint Infection in Total Knee Arthroplasty
The primary aim of the study is to compare two methods for a relationship with total knee infection: regular changing of dressings and not changing dressings.
- Conditions
- Infection, Surgical Site Infection, Prosthetic Infection, Wound Infection
- Trial name
- NCT04346875
- Testing
- Regularly changing of dressing, No application
- Volunteers
- 842 people
- Sponsor
- Bezmialem Vakif University
Anterior Cruciate Ligament Injury
The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruction
The overall aim of this study is to determine the effect of the knee flexion angle (KFA) of either 0 degrees, or 30 degrees (measured by sterile goniometer) during anterior cruciate ligament (ACL) fixation on postoperative…
- Trial name
- KFA-FIRM (NCT03875807)
- Testing
- ACLR done at 0 degrees KFA, ACLR done at 30 degrees KFA
- Volunteers
- 204 people
- Sponsor
- Women's College Hospital
ACL Tear, ACL Sprain
Knee vs. Ankle Training on Knee Mechanics After ACLR
This study will be conducted to investigate if there is any difference between starting rehabilitation program after ACL reconstruction with knee joint training followed by ankle joint training and starting it with ankle joint…
- Conditions
- ACL Tear, ACL Sprain, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
- Trial name
- NCT05241795
- Testing
- Knee then Ankle rehabilitation protocol, Ankle then Knee rehabilitation protocol
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- October 6 University
Cartilage Injury
Clinical Study of Decalcification Bone Scaffold for Cartilage Lesions of the Knee
The trial evaluates the clinical efficacy and safety of decalcification bone scaffold for cartilage lesions of the knee. Half of participants will receive decalcification bone scaffold combined with microfracture, while the other…
- Trial name
- NCT03321812
- Testing
- decalcification bone scaffold, microfracture
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
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